# User:Fuse809

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Please read the section on my philosophies before writing on my talk page as it will probably answer some questions you have about my work and how you should reply.

My real name is Brenton Horne, I am interested in mathematics, pharmacy, physics and medicine and am a pharmacy student. I live in Townsville, Queensland, Australia The current date and time in Townsville is Sunday 19 February, 18:57.[1]

I do 3D and 2D chemical structure images, if you have one you'd like to request, feel free to on my talk page. I also attempt IPA keys on pages with names sufficiently difficult for pronunciation to be a problem with the help of this page. Likewise I also attempt translations of drug info using Google Translate. For instance a summary of product characteristics (SPC) for piritramide may be found here and a translation of a SPC for tilidine may be found here.

I have also deposited structures on the Crystallography Open Database, e.g., ID 1519159 and 1519190. I am currently working on a local Wiki on medicine-related matters, including preliminary science. It currently has over 750 pages and over 2,000 files.

## My chemical structures

I create structural images to satisfy everyone, not just me. I try to use the structures provided by ChemSpider or PubChem just to ensure reliability. The software I use for chemical structure drawing is:

• MarvinSketch/ChemSpider/PubChem (for the production of MOL files), ChemSketch (to create WMF files in ACS style) and then Scribus to convert the WMF to a SVG file (these are the images with 2DACS tags).
• MarvinSketch (with settings according to WP:Chem/Structures) to create SVG files (2DCSD tag). Sometimes I do these images wrong the first time in that I do not crop them as well as I can and when I upload a better scaled cropped version I give it the tag 2DCSDS. Structures drawn in MarvinSketch often have whitespace in their atom labels that are due to MarvinSketch itself, e.g., see this forum topic I started about these spaces. The best solution for removing them is to use a text editor (e.g., Atom or Sublime Text) and search for xml:space="preserve" and replace it with nothing (in other words set the text editor up such that it deletes all these pieces of XML code). After this I use Inkscape to crop them. Sometimes I accidentally draw the opioids in a less conventional way, so when I fix this I give them the tag 2DCSDT.
• MarvinSketch (to create SDF files) → OpenBabel (SDF->PDB; also adds hydrogens with this tool) → QuteMol (PDB->GIF). (3Dan tag). Unfortunately these images do not display double bonds in a way distinct from single bonds and hence I'm now favouring the 3DanJ images.
• I also create 3D animated GIF files of drug molecules using Jmol (to create usually about 60 PNG images spaced 3 degrees apart) and GIMP to animate them into gif files. (3DanJ tag). This is the code I use to create these images:
background white;##
name = "./images/Work0000.png";
nFrames = 60;
nDegrees =6 ;
thisFrame = 0;
width = 539;
height = 260;

message loop;
thisFrame = thisFrame + 1;
fileName = name.replace("0000","" + ("0000" + thisFrame)[-4][0]);
rotate y @ndegrees;
frame next; # only use this if you have a multiframe file.
refresh;
write image @width @height @fileName;
if (thisFrame < nFrames);goto loop;endif;

• I create 3D animated pictures of biomolecules, most often joined with their respective ligand(s) using the PDB files found here, Jmol and then PhotoScape or GIMP to convert these PNG images to GIF format. I usually colour shapely, unless doing so will make the ligand(s) difficult to see. I have now decided to use the name PDBID3DanJ for these images; for instance, https://en.wikipedia.org/wiki/File:3NT13DanJ.gif for this protein-ligand complex 3NT1.
Structures (Hidden as one of the animated images is insanely high resolution)
Image type Example's name Image example
2DACS Piritramide
2DCSD Dextropropoxyphene
3Dan Fluoxetine
3DanJ Piritramide
Biomolecule High resolution structure of naproxen:COX-2 complex. (PDB ID:3NT1)

I upload all these images to commons now, as per the request by Leyo on my talk page. For a comprehensive list of images I've uploaded see Commons:Special:ListFiles/Fuse809.

## Extended edit summaries

Edit summaries I find can be limiting, so if an edit summary is too long to fit I may add them here [1]. Please comment on them here [2] if you feel the need.

I have ten philosophies when it comes to Wikipedia:

• The five pillars of Wikipedia are the law.
• Style guides are the guidelines, if you stray from them, in a way that isn't well-justified, you better have a good reason and if you do not you should not be surprised if somebody, yes, including myself, reverts your edits.
• Consensus is the legislator. If you show me consensus against what I did I will admit I was wrong and never do it again!
• If you make any changes to a page then the burden of proof for any additions you make is ON YOU. If you do not manage to keep to this standard then people (including myself) may and should feel no guilt in reverting your edits!
• If you have a problem with my work, please don't just stop there, tell me specifically what is wrong. I have seen some people not bother to give me any specifics and I have deleted their comments from my talk page as I did ask them, repeatedly, what specifically they wanted me to change, but they didn't bother to. Otherwise, answer me, what good does your criticism do if you don't even bother telling me what is specifically wrong? I am willing to accept people challenging the way I draw structures and edit Wikipedia, I may even thank you for it and admit I was wrong! But if and only if they're willing to actually have a conversation with me and not just dump on me. After all, I think that's what a psychiatrist is for.
• I only create structural images and replace those on Wikipedia articles if and only if I see the picture there are inferior quality, most often due to the distance between bonds, their angles, or sometimes because the previous image wasn't cropped. I only replace them with images that are acceptable according to WP:CSDG.
• Primary sources DO NOT belong in the lead, unless there's a good reason for it. The reasoning is simple, if the experts can't agree on the validity of the info in primary sources enough to sit down and write a review article on it then why should we mention it in Wikipedia articles as fact? Plus, of course, secondary sources do take into account unpublished results, whereas primary sources usually do not unless they have an extensive and unbiased introductory section. I do not have a problem if you use primary sources and then say the info from it is pure conjecture or if you use the Introduction section of primary sources to support your info (as the intro is by definition a minireview, in effect).
• International Nonproprietary Names (INNs) should always be the title used for drug articles. This is a change I have argued for the articles: amfetamine, dexamfetamine, metamfetamine, etc. But for some reason everybody seems to favour the more conventional spelling (i.e. ones that include the letters "ph").
• Something is better than nothing; I would rather some information be on an article from a primary source, than there be no information, whatsoever. Like I understand, for some things like alternative medicine, where some user might have a rant about how good the stuff is with little, if any, high-quality evidence, and I can understand why you should, definitely, remove those sort of rants but I would rather you put something than nothing when it comes to alternative medicine articles. Like, for acetylcarnitine, I think we should mention the putative antidepressant and analgesic properties, even if we say it is purely conjecture.
• "The Devil is in the details" is very true. This is why I am so pedantic. People tend to be very obsessed with the big details, hence it can be very easy to miss the little, yet important details.

## My preferences

I absolutely adore Wikipedia's in-built referencing style, especially for medicine, mostly because it is so exhaustive, that is, it lists PMIDs, PMCs, DOIs (and gives these identifiers hyperlinks to the respective page associated with them) and other URLs, if free full-text is available and the format of said URL if applicable. I personally think that every article would be far better if we just used the in-built referencing style, plus the rp operator, when referencing books.

I dislike BKChem-created structural images, mostly as I know personally the tool is pretty basic and most of the images look pretty scrappy to me at least. But I am trying to avoid replacing images solely for this reason, usually due to the fact there is empty, unused space in the image, which is typical of BKChem images.

Although I realize many members of WikiProject Medicine disapprove of Medscape/eMedicine I do sometimes use it, usually when it gives one information that's difficult to come across in other secondary sources. I realize it changes and while I am all for it being knocked out of articles in which the information contained therein can be just as easily found in a static secondary source, I still favour it over primary sources or no information at all. I tend to find that eMedicine tends to be pretty static and accurate. Like there's the odd minor grammatical or spelling errors that pop up and get amended but usually the information stays pretty static unless it should be updated as it is out-of-date.

## My profiles

Blogger Link My blog for medicine-related matters. Disclaimer: NOT for personal medical information.
Facebook Link Feel free to send me a friend request, I will likely accept. Just tell me that this is how you found my profile, as otherwise I may find your request a little odd. All I ask is do not offend any of my friends and think before you tag me in anything.

1 Using to create a section on flavonoids
2 Cancers in Australia.
3 Blood cancers in Australia.
4 Antineoplastic table I created.
5 Lisdexamfetamine page edit.
6 Comparison of accepted autoimmune diseases.
7 Renal cell carcinoma page edit.
8 A page I use to create a reference list for something I'm working on.
9 The opioids.
10 Table of the opioids.

### Introduction

#### Help

Plus, if you would like help and can't find guidance anywhere else, you can always leave {{help me}} enclosed on your talk page.