User:Indlekoferw/Sandbox Gerhard Schwarz
Gerhard Schwarz | |
|---|---|
 Gerhard Schwarz (1989) | |
| Born | 3 February 1930 |
| Nationality | German |
| Scientific career | |
| Fields | Biophysical chemistry |
| Institutions | University of Göttingen, University of Pennsylvania , Biozentrum University of Basel |
Gerhard Schwarz (born 3 February 1930 in Bremen) is a German physicist and one of the founding fathers of the Biozentrum of the University of Basel, Switzerland.[1]
Life[edit]
Gerhard Schwarz studied 1950-1955 at the University of Göttingen; in 1958, he received his Ph.D. from the same institution for work performed under supervision of the later Nobel Laureate Manfred Eigen. Interrupted only by postdoctoral training at the University of Pennsylvania 1960-1962, Gerhard Schwarz continued his research in Eigen’s group at the Max Planck Institute for Physical Chemistry until 1969. After his habilitation 1968 at the Braunschweig University of Technology (TU Braunschweig), he was appointed Professor of Biophysical Chemistry at the Biozentrum of the University of Basel. Schwarz retired in 2000.[2]
Work[edit]
In his work, Gerhard Schwarz investigated the molecular mechanisms displayed by membrane-active substances with a particular emphasis on the physicochemical aspects of the interactions of peptides and proteins with lipid membranes. Towards this goal, Schwarz continuously advanced kinetic measurement methods for the study of rapid chemical processes.[3] Another important achievement was the development of the so-called “mass conservation plot” method, which allowed the model-free analysis of binding isotherms and the elucidation of the thermodynamic processes involved.[4] His work provided significant insights into the molecular mechanisms of a variety of membrane functions such partitioning equilibria, pore formation, antibiotic permeation, and binding studies.
Awards and honors[edit]
- 1967 Nernst-Haber-Bodenstein Prize of the German Bunsen Society for Physical Chemistry[5]
- 1994 Boris Rajewsky Prize for Biophysics (Max Planck Institute, Frankfurt)
Notable publications[edit]
- Schwarz G. (2000). A universal thermodynamic approach to analyze biomolecular binding experiments. Biophys. Chem.; 86: 119-29. PMID 11026677
- Hellmann N. and Schwarz G. (1998). Peptide-liposome association. A critical examination with mastoparan X. Biochim. Biophys. Acta, 267-277. PMID 9518645
- Taylor SE, Schwarz G. (1997). The molecular area characteristics of the HIV-1 gp41-fusion peptide at the air/water interface. Effect of pH. Biochim Biophys Acta.;1326: 257-64. PMID 9218556
- Schwarz G, Blochmann U. (1993). Association of the wasp venom peptide mastoparan with electrically neutral lipid vesicles. Salt effects on partitioning and conformational state. FEBS Lett.; 318:172-6. PMID 8440373
- Stankowski S, Schwarz G. (1989). Lipid dependence of peptide-membrane interactions. Bilayer affinity and aggregation of the peptide alamethicin. FEBS Lett.;250: 556-60. PMID 2753150
References[edit]
- ^ "The Biozentrum – its history and role". Biozentrum.unibas.ch. Retrieved 2014-12-03.
- ^ "Biozentrum Emeriti". Biozentrum.unibas.ch. Retrieved 2014-12-03.
- ^ "Kinetic Analysis by Chemical Relaxation Methods". aps.org. Retrieved 2014-12-03.
- ^ "Negative cooperativity and aggregation in biphasic binding of mastoparan X peptide to membranes with acidic lipids". sciencedirect.com. Retrieved 2014-12-03.
- ^ "Nernst-Haber-Bodenstein-Preis". bunsen.de. Retrieved 2014-12-03.
External links[edit]
- Gerhard Schwarz in der Forschungsdatenbank des Schweizerischen Nationalfond, snf.ch. Retrieved 2014-12-3.
{{Persondata | NAME = Gerhard Schwarz | ALTERNATIVE NAMES = | SHORT DESCRIPTION = German Physicist | DATE OF BIRTH = 3 February 1930 | PLACE OF BIRTH = [[Bremen]] | DATE OF DEATH = | PLACE OF DEATH = }} {{DEFAULTSORT:Schwarz, Gerhard}} [[Category:1930 births]] [[Category:Living people]] [[Category:People from Bremen]] [[Category:University of Göttingen alumni]] [[Category:University of Pennsylvania alumni]] [[Category:University of Basel faculty]] [[Category:University of Basel alumni]] [[Category:Biozentrum University of Basel]] Category:1930 births