User:Julialturner/HLA-DRB1

HLA-DRB1
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	1A6A, 1BX2, 1YMM, 2WBJ,%%s1AQD, 1DLH, 1FYT, 1HXY, 1JWM, 1JWS, 1JWU, 1KG0, 1KLG, 1KLU, 1LO5, 1PYW, 1R5I, 1SEB, 1SJH, 1T5W, 1T5X, 2FSE, 2G9H, 2IAM, 2IAN, 2ICW, 2IPK, 2OJE, 2XN9, 3L6F, 3PDO, 3PGC, 3PGD, 3QXA, 3QXD, 3S4S, 3S5L, 4AEN, 4AH2, 4C56, 4E41, 4FQX, 4GBX, 4I5B, 4OV5, 4X5W, 4X5X,%%s1D5M, 1D5X, 1D5Z, 1D6E, 1J8H, 2SEB, 3O6F, 3T0E, 4IS6, 4MCY, 4MCZ, 4MD0, 4MD4, 4MD5, 4MDI, 4MDJ, 4Y19, 4Y1A
Identifiers
Aliases	HLA-DRB1, DRB1, DRw10, HLA-DR1B, HLA-DRB, SS1, major histocompatibility complex, class II, DR beta 1
External IDs	OMIM: 142857 HomoloGene: 136635 GeneCards: HLA-DRB1
Gene ontology
Molecular function	• peptide antigen binding; • MHC class II receptor activity; • GO:0001948, GO:0016582 protein binding; • MHC class II protein complex binding;
Cellular component	• integral component of membrane; • endocytic vesicle membrane; • clathrin-coated endocytic vesicle membrane; • endosome; • Golgi apparatus; • trans-Golgi network membrane; • endoplasmic reticulum membrane; • membrane; • late endosome membrane; • Golgi membrane; • plasma membrane; • transport vesicle membrane; • MHC class II protein complex; • lysosomal membrane; • endoplasmic reticulum; • ER to Golgi transport vesicle membrane; • lysosome; • integral component of lumenal side of endoplasmic reticulum membrane; • endosome membrane; • external side of plasma membrane; • cell surface; • extracellular exosome;
Biological process	• antigen processing and presentation; • antigen processing and presentation of exogenous peptide antigen via MHC class II; • immune system process; • interferon-gamma-mediated signaling pathway; • immunoglobulin production involved in immunoglobulin-mediated immune response; • antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; • humoral immune response mediated by circulating immunoglobulin; • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response; • peptide antigen assembly with MHC class II protein complex; • T cell receptor signaling pathway; • adaptive immune response; • negative regulation of interferon-gamma production; • inflammatory response to antigenic stimulus; • protein tetramerization; • regulation of interleukin-4 production; • negative regulation of T cell proliferation; • T-helper 1 type immune response; • positive regulation of insulin secretion involved in cellular response to glucose stimulus; • T cell costimulation;
	Sources:Amigo / QuickGO
Orthologs
	3123
	n/a
ENSG00000236884; ENSG00000206240; ENSG00000229074; ENSG00000196126; ENSG00000206306;
	ENSG00000228080
	n/a
	P01911
	n/a
	NM_001243965; NM_002124; NM_001359193; NM_001359194
	n/a
	NP_001230894; NP_002115; NP_001346122; NP_001346123; NP_002115.2
	n/a
	Wikidata
View/Edit Human

Long list of GO terms for testing

^ "Human PubMed Reference:".

[1] "Human PubMed Reference:".

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