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Within the section Quadruplex prediction techniques, a source describing a way the predictions are undergone as well as what tools are used. A notable source was found to be [1], the source being a review described Circular dichroism (CD) spectroscopy and its uses. CD spectroscopy is a to shown how it is able to identify the Quadruplex structures as well as predict the structures folding.

multiple run on sentences within the section Quadruplex topology

Are statements such as "This has become an increasingly large field of research." in the section Ligands which bind quadruplexes necessary? The comment does not have factual evidence supporting the claim nor does it add any benefit to section.

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  1. ^ Huppert, Julian Leon (2008-06-23). "Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes". Chemical Society Reviews. 37 (7). doi:10.1039/B702491F. ISSN 1460-4744.