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this page was created during my Training Workshop and kept being used for 'Hippocampal Sclerosis' page.
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{ Summary / Overview }
History
[edit]Hippocampal sclerosis was first described in 1880 by Wilhelm Sommer.
Causes
[edit]Much remains unknown about hippocampal sclerosis associated with ageing.[1]
Diagnosis
[edit]Hippocampal sclerosis is nowadays easy to detect with MRI.
Symptoms
[edit]Histopathological hallmarks of hippocampal sclerosis include segmental loss of pyramidal neurons, granule cell dispersion and reactive gliosis.
Prevalence, laterality, and comorbidity. [2]
Meisal temporal lobe epilepsy
[edit]Meisal Temporal Lobe Epilepsy [3] [4] Hippocampal Sclerosis with and without Meisal temporal lobe epilepsy [3]
Other
[edit]A long and ongoing debate addresses the issue of whether hippocampal sclerosis is the cause or the consequence of chronic, pharmacoresistant seizure activity.
Treatments
[edit]See also
[edit]References
[edit]- ^ Nelson, PT; Schmitt, FA; Lin, YS; Abner, EL; Jicha, GA; Patel, E; Thomason, PC; Neltner, JH; Smith, CD; Santacruz, KS; Sonnen, JA; Poon, LW; Gearing, M; Green, RC; Woodard, JL; Van Eldik, LJ; Kryscio, Rj. Hippocampal sclerosis in advanced age: clinical and pathological features. Brain 2011; 134(5): 1506-1518.
- ^ Zarow, C; Weiner, MW; Ellis, WG; Chui HC. Prevalence, laterality, and comorbidity of hippocampal sclerosis in an autopsy sample. Brain and Behavior 2012; 2(4): 435-442.
- ^ a b Blumcke,I; Coras R; Miyata, H; Ozkara, C. Defining Clinico-Neuropathological Subtypes of Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis. BRAIN PATHOLOGY 2012; 22(3): 402-411
- ^ Asuman O. V.; Serap S; Hamit A; Abdurrahman C. Prognosis of patients with mesial temporal lobe epilepsy due to hippocampal sclerosis. Epilepsy Research 2009; 85(2): 206-211