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Guadalupe Sabio is a Spanish biochemist and principal investigator at the Spanish National Center for Cardiovascular research in Madrid best known for her research into diseases associated with obesity and the role of stress kinases in diabetes, liver cancer and heart disease. She has had an extensive career in the sciences, ranging from receiving her doctorate in veterinary medicine to receiving a variety of prestigious fellowships and awards, particularly a Ramon Y Cajal contract, intended to inject the Spanish scientific community with scientists who have had research experience abroad.

(Shown second from the right, back row)
Guadalupe Sabio Buzo
Born June 4, 1977

Badajoz, Extremadura, Spain

Nationality Spanish
Alma Mater University of Extremadura
Scientific Fields Veterinary medicine, metabolism, obesity
Known for Expertise in disease associated with stress kinases

Education[edit]

Dr. Sabio graduated from the School of Veterinary Medicine at the University of Extremadura, in Badajoz, Spain in 2000. She then went on to complete a PhD in 2005 at the University of Extremadura and the MRC Protein Phosphorylation Unit in Dundee, in the United Kingdom. She completed her postdoc working with Dr. Roger David at the University of Massachusetts Medical School.

Research Interests[edit]

Dr. Sabio used her training as a veterinarian to complement her later career, as she learned a huge amount about diseases. Her thesis work during her PhD was focused on role of the p38 pathway and the redundancy of two p38 kinases in metabolism and diseases such as diabetes. The p38 pathway is a kinase that works to phosphorylate various proteins, and may have implications with over expression in obesity. During her postdoc at UMass Medical, she worked with Dr Davis studying the tissue-specific roles of cell signaling in diabetes. She then was able to return to Spain under a Ramón y Cajal contract to study and work at the Spanish National Center for Cardiovascular research as the lead researcher on a team of 11 people. These Ramón y Cajal contracts are funded by the Spanish government to encourage scientists with experience abroad to return to Spain and work in the sciences there.

Career & Achievements[edit]

Since returning to Spain, Dr. Sabio has been focusing on stress-activated kinases and their role in metabolic syndrome. She runs a lab at the Spanish Center for Cardiovascular Research where she is also an assistant professor. Since working in Spain at the Spanish National Center for Cardiovascular research, she has since won the Star of the Community of Madrid Award, presented to her on International Women's Day, "highlighting that her work has been recognized by important organizations and her work has been published in scientific journals of recognized international prestige".

Personal Life[edit]

Dr. Sabio is married to a scientist and has three sons, including twins.

References[edit]

“Guadalupe Sabio Buzo.” OMICS International, biography.omicsonline.org/spain/national-cardiovascular-research-center-carlos/guadalupe-sabio-buzo-86867.

Jurez, Ana Snchez. “Guadalupe Sabio: 'La Base Del.” ELMUNDO, 27 Mar. 2014, www.elmundo.es/yodona/2014/03/27/5333e811e2704e760a8b456a.html.

“Stress Kinases in Diabetes, Cancer and Cardiovascular Disease.” Sabio Lab - at the CNIC, www.sabiolab.com/.

Lambert, Hazel. “Guadalupe Sabio | MRC PPU.” MRC Protein Phosphorylation and Ubiquitylation Unit, www.ppu.mrc.ac.uk/about-us/alumni-interviews/guadalupe-sabio.

“Stress Kinases in Diabetes, Cancer and Cardiovascular Disease.” CNIC - From Research to Health, www.cnic.es/en/investigacion/stress-kinases-diabetes-cancer-and-cardiovascular-disease.

“Guadalupe Sabio Buzo.” CNIC - From Research to Health, www.cnic.es/en/guadalupe-sabio-buzo.

“La Investigadora Guadalupe Sabio Recibe La Estrella De La Comunidad De Madrid En El Día Internacional De La Mujer.” CNIC - Desde La Investigación a La Salud, 7 Mar. 2014, www.cnic.es/es/noticias/investigadora-guadalupe-sabio-recibe-estrella-comunidad-madrid-dia-internacional-mujer.