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User:Mr. Ibrahem/Hepatitis B immune globulin

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Mr. Ibrahem/Hepatitis B immune globulin
Clinical data
Trade namesHepaGam B, Nabi-HB, Zutectra, others
AHFS/Drugs.comMonograph
Pregnancy
category
Routes of
administration		Intramuscular, intravenous
Drug classAntibodies[2]
Legal status
Legal status
Pharmacokinetic data
Onset of actionImmediate[3]
Duration of action3 to 6 months[3]
 ☒NcheckY (what is this?)  (verify)

Hepatitis B immunoglobulin (HBIG) is a medication used to prevent hepatitis B following exposure.[2] This includes in newborns following birth to a women who is hepatitis B positive, following liver transplant in someone with hepatitis B, and following exposure in those who are not immune.[2] It may be given by injection into a vein or muscle.[2] Hepatitis B vaccine may be given at the same time, but at a different site on the body.[4][5]

Common side effects include pain at the site of injection, headache, nausea, lightheadedness, and fever.[2] Other side effects may include allergic reactions.[2] It can be used in pregnancy when required.[2] It is antibodies directed against hepatitis B surface antigen (anti-HBs).[2]

Hepatitis B immunoglobulin come into medical use in 1974.[3] It is available as a generic medication.[4] In the United Kingdom 500 units costs the NHS about £500 as of 2021.[4] In the United States it costs about 830 USD for 5 ml.[6] It is made from human plasma.[2]

References

  1. ^ a b "Hepatitis b immune globulin Use During Pregnancy". Drugs.com. 3 August 2020. Archived from the original on 21 October 2020. Retrieved 13 September 2020.
  2. ^ a b c d e f g h i j k "Hepatitis B Immune Globulin Monograph for Professionals". Drugs.com. Archived from the original on 24 August 2019. Retrieved 9 December 2021.
  3. ^ a b c Zuckerman, JN (July 2007). "Review: hepatitis B immune globulin for prevention of hepatitis B infection". Journal of medical virology. 79 (7): 919–21. doi:10.1002/jmv.20816. PMID 17516515.
  4. ^ a b c "14. Vaccines". British National Formulary (BNF) (82 ed.). London: BMJ Group and the Pharmaceutical Press. September 2021 – March 2022. pp. 1343–1346. ISBN 978-0-85711-413-6.{{cite book}}: CS1 maint: date format (link)
  5. ^ Richman, Douglas D.; Whitley, Richard J.; Hayden, Frederick G. (10 July 2020). Clinical Virology. John Wiley & Sons. p. 365. ISBN 978-1-55581-943-9. Archived from the original on 11 December 2021. Retrieved 10 December 2021.
  6. ^ "Hepatitis B Immune Globulin Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 10 December 2021.
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