User:Mr. Ibrahem/Lactitol
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| Clinical data | |
|---|---|
| Trade names | Importal, Pizensy, Lacty, others |
| Other names | Lactit, lactositol, lactobiosit[1], Lactitol hydrate (JAN JP) |
| License data | |
| Routes of administration | By mouth |
| Drug class | Osmotic laxative[2] |
| Legal status | |
| Legal status |
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| Identifiers | |
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| Chemical and physical data | |
| Formula | C12H24O11 |
| Molar mass | 344.313 g·mol−1 |
| 3D model (JSmol) | |
| Melting point | 146 °C (295 °F) |
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Lactitol is a sugar alcohol and laxative.[1] As a laxative it is used for chronic constipation of unknown cause.[2] It is taken by mouth.[2] It is also used as a replacement sweetener in low calorie foods.[1]
Common side effects include flatulence, diarrhea, abdominal distension, and increased blood pressure.[2] It is an osmotic laxative and works by pulling water into the small intestine.[2] It has about 30–40% of the sweetness of sucrose.[1]
Lactitol was first described in 1920 by Senderens.[1] It was approved for medical use in the United States in 2020.[2] It is generally recognized as safe in the United States and allowed as a sweetener in Europe.[1] Commercially it was sold for about 2.5 USD per kilogram in 2009.[3] It is made from lactose.[1]
References[edit]
- ^ a b c d e f g O'Brien-Nabors, Lyn (8 June 2001). Alternative Sweeteners, Third Edition, Revised and Expanded. CRC Press. p. 297. ISBN 978-0-8247-0437-7. Archived from the original on 12 November 2022. Retrieved 4 November 2022.
- ^ a b c d e f g h "DailyMed - PIZENSY- lactitol powder, for solution". dailymed.nlm.nih.gov. Archived from the original on 25 October 2020. Retrieved 4 November 2022.
- ^ Illanes, Andrés; Guerrero, Cecilia; Vera, Carlos; Wilson, Lorena; Conejeros, Raúl; Scott, Felipe (6 July 2016). Lactose-Derived Prebiotics: A Process Perspective. Academic Press. p. 100. ISBN 978-0-12-802745-5. Archived from the original on 12 November 2022. Retrieved 4 November 2022.