User:Mr. Ibrahem/Oritavancin
Clinical data | |
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Pronunciation | /oʊˌrɪtəˈvænsɪn/ oh-RIT-ə-VAN-sin |
Trade names | Orbactiv, Kimyrsa, Tenkasi, others |
Other names | LY333328 |
AHFS/Drugs.com | Monograph |
MedlinePlus | a614042 |
License data |
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Routes of administration | Intravenous |
Drug class | Antibiotic (lipoglycopeptide)[1] |
Legal status | |
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Identifiers | |
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Chemical and physical data | |
Formula | C86H97Cl3N10O26 |
Molar mass | 1793.12 g·mol−1 |
3D model (JSmol) | |
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Oritavancin, sold under the brand name Orbactiv among others, is an antibiotic used to treat skin and skin structure infections such as cellulitis and skin abscesses.[1][4] It is also effective against MRSA.[1] It is given by injection into a vein.[1]
Common side effects include diarrhea, nausea, dizziness, headache, itchiness, fever, and liver problems.[1] Safety in pregnancy is unclear.[5] It is a glycopeptide specifically a lipoglycopeptide and is similar to vancomycin.[1] It works by stopping bacteria from making their cell wall.[4]
Oritavancin was approved for medical use in the United States in 2014 and Europe in 2015.[1][4] In the United States a course of treatments costs about 3,000 USD.[6] It; however, is not commercially available in the United Kingdom or Europe as of 2021.[7]
References[edit]
- ^ a b c d e f g h i "Oritavancin Monograph for Professionals". Drugs.com. Archived from the original on 28 January 2021. Retrieved 8 November 2021.
- ^ "Orbactiv- oritavancin injection, powder, lyophilized, for solution". DailyMed. Archived from the original on 24 March 2021. Retrieved 18 December 2020.
- ^ "Kimyrsa- oritavancin diphosphate injection, powder, lyophilized, for solution". DailyMed. Archived from the original on 19 April 2021. Retrieved 31 March 2021.
- ^ a b c d e "Orbactiv EPAR". Archived from the original on 2020-12-28. Retrieved 2021-09-05.
- ^ "Oritavancin Use During Pregnancy". Drugs.com. Archived from the original on 29 November 2020. Retrieved 8 November 2021.
- ^ "Orbactiv Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 13 June 2016. Retrieved 8 November 2021.
- ^ "Oritavancin". SPS - Specialist Pharmacy Service. 28 September 2015. Archived from the original on 9 November 2021. Retrieved 8 November 2021.