User:Mr. Ibrahem/Tolnaftate

Mr. Ibrahem/Tolnaftate
Clinical data
Trade names	Tinactin, Absorbine, others
Other names	2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate
AHFS/Drugs.com	Monograph
MedlinePlus	a682617
Drug class	Thiocarbamate
Legal status
Legal status	In general: Over-the-counter (OTC);
Identifiers
	IUPAC name O-2-Naphthyl methyl(3-methylphenyl)thiocarbamate;
Chemical and physical data
Formula	C19H17NOS
Molar mass	307.41 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	110 to 111.5 °C (230.0 to 232.7 °F)
	SMILES S=C(Oc2ccc1c(cccc1)c2)N(c3cc(ccc3)C)C;
	InChI InChI=1S/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3 ; Key:FUSNMLFNXJSCDI-UHFFFAOYSA-N ;
	(what is this?) (verify)

Tolnaftate, sold under various brand names, is a medication used to treat fungal infections including jock itch, athlete's foot, ringworm, and pityriasis versicolor.^[2] It is applied to the skin.^[2] It comes in cream, powder, spray and solution forms.^[2]

Common side effects include skin irritation.^[2] It is a thiocarbamate.^[2]

Tolnaftate was developed around 1962.^[3] It is available as a generic medication and over the counter.^[2]^[4] In the United States a 28 gram tube of medication costs about 6 USD as of 2021.^[4] It is also available in the United Kingdom without a prescription.^[5]

References

^ "International Non-Proprietary Names for Pharmaceutical Preparations. Recommended International Non-Proprietary names (Rec. I.N.N.): List 6" (PDF). World Health Organization. Archived (PDF) from the original on 10 August 2020. Retrieved 12 November 2016.
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ "Tolnaftate Monograph for Professionals". Drugs.com. Archived from the original on 28 January 2021. Retrieved 6 October 2021.
^ Greenwood, David (21 February 2008). Antimicrobial Drugs: Chronicle of a Twentieth Century Medical Triumph. OUP Oxford. p. 360. ISBN 978-0-19-953484-5. Archived from the original on 9 October 2021. Retrieved 6 October 2021.
^ ^a ^b "Compare Tolnaftate Prices - GoodRx". GoodRx. Retrieved 6 October 2021.
^ BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 1294. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)

[INN-1] "International Non-Proprietary Names for Pharmaceutical Preparations. Recommended International Non-Proprietary names (Rec. I.N.N.): List 6" (PDF). World Health Organization. Archived (PDF) from the original on 10 August 2020. Retrieved 12 November 2016.

[AHFS2021-2] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ "Tolnaftate Monograph for Professionals". Drugs.com. Archived from the original on 28 January 2021. Retrieved 6 October 2021.

[3] Greenwood, David (21 February 2008). Antimicrobial Drugs: Chronicle of a Twentieth Century Medical Triumph. OUP Oxford. p. 360. ISBN 978-0-19-953484-5. Archived from the original on 9 October 2021. Retrieved 6 October 2021.

[GX2021-4] "Compare Tolnaftate Prices - GoodRx". GoodRx. Retrieved 6 October 2021.

[BNF80-5] BNF (80 ed.). BMJ Group and the Pharmaceutical Press. September 2020 – March 2021. p. 1294. ISBN 978-0-85711-369-6.{{cite book}}: CS1 maint: date format (link)

[1]

[2]

[3]

[4]

[5]