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CRISPR

Off-target

[edit]

Schaefer's team reported off-target disadvantages of CRISPR genome editing in 2017, raised great concern on CRISPR application in human related disease research. More and more genome level tests are taking into concern to verify its influence on non-target site to reassessment CRISPR off-target issue. [1]

  1. ^ "CRISPR off-targets: a reassessment". Nature Methods. 15 (4): 229–230. 2018-03-30. doi:10.1038/nmeth.4664. ISSN 1548-7091.