Eosinophilic cellulitis

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Eosinophilic cellulitis
Classification and external resources
Specialty dermatology
ICD-10 L98.3 (ILDS L98.300)
DiseasesDB 34888

Eosinophilic cellulitis (also known as Wells' syndrome from George Crichton Wells who first described it[1]) is a skin condition characterized by plaques that resemble cellulitis.[2][3]

Eosinophilic cellulitis is of unknown etiology, though it is suspected to have an allergic and/or autoimmune component. There are documented cases of it being caused by flea (and other insect) bites and it has been seen in conjunction with Churg-Strauss disease, though many cases are considered idiopathic. In addition, it has also been reported in a case of IgG4-related disease.[4]

It is included in the raredisease.org database.

Typical treatment is with prednisone.

See also[edit]


  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  2. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. p. 144. ISBN 0-7216-2921-0. 
  3. ^ González Martínez F; Santos Sebástián MM; Navarro Gómez ML; Saavedra Lozano J; Hernández Sampelayo T (April 2009). "Eosinophilic cellulitis: Wells syndrome". Anales de Pediatría (Barc) (in Spanish) 70 (5): 509–11. doi:10.1016/j.anpedi.2009.01.007. PMID 19375989. 
  4. ^ Takashi Karashima; Yoshinori Taniguchi; Tsutomu Shimamoto; Tomoya Nao; Hiroshi Nishikawa; Satoshi Fukata; Masayuki Kamada; Keiji Inoue; Kentaro Oko; Hideki Nakajima; Shigetoshi Sano; Manabu Matsumoto; Naoto Kuroda; Yoshihiro Kamei; Taro Shuin (9 December 2014). "IgG4-related disease of the paratestis in a patient with Wells syndrome: a case report". Diagnostic Pathology 9. doi:10.1186/s13000-014-0225-5. PMC 4265405. PMID 25337295. 225.