Wikipedia:USEP/Courses/JHU MolBio Ogg SP14/Group 82A

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Final Progress Report[edit]

(from Julia)

  • All writing contributions were prose.
  • Spent a large amount of time on the image in morphology. Unfortunately, paraptosis does not have images we can use, so I hand-sketched a rough idea, and spent a lot of time in inkjet for the posted result. It was quite an informative experience, and I have a new found appreciation for flow charts and diagrams available on the internet.
  • Additionally, after loading the image, I spent time learning about alt.
  • As well as, spent a significant amount of time reading How to place an image and Template:Annotated image. Once the image was placed I learned how to incorporate the crop suggestions found here, Template:Annotated image/doc/Samples.
  • Did not see any new comments/suggestions that immediately needed attention, I will, however, reread and address anything outstanding (Lisa and I have done a good job at incorporating suggestions and making edits as they arose, so I don't believe this will be much, if at all)
  • Overall, my interactions with other students and class modulators was very informative. To my knowledge, there was no "significant help" from other "Wikipedia editors".

(from Lisa)

  • Majority of contributions were prose: cleaned up some overly technical language, and some minor errors. Added a short "See also" section and rearranged the layout a bit. Added a link to our article from the apoptosis page.
  • Overall improvements: our article had not yet been created, so everything present was added by myself and Julia, including finding/creating images and a table. I'm not aware of any significant outside help, but all of the reviewers provided helpful suggestions that we have incorporated.

Unit 12 Progress Report[edit]

(from Julia)

  • The majority of this units contributions were prose
  • Responded to user reviews and suggestions
  • Will spend time linking, as I wrote more material I did not link as often as I should, as well as comments from reviews indicated areas still lacking.


(from Lisa)

  • Majority of contributions were prose; added more to cancer, a neurodegenerative example, and non-animal examples.
  • Created table summarizing major differences from other pathways
  • Responded to comments from talk page

Unit 10 Progress Report[edit]

(from Julia)

  • The majority of this units contributions were prose - contributions to the following subsections were made: (1) Pathway (2) Structural Proteins (3) Signal Transduction (4) Mitochondrial Proteins
  • Correction of cite error in reference list of source 4 was made.
  • Responded to /incorporated appropriate suggestions from talk page from other users

(from Lisa)

  • All contributions were prose; expanded lead section, added more information to cancer section and removed subsections.
  • Responded to comments from talk page.

Unit 8 Progress Report[edit]

(from Julia) Officially started the article page. I used ideas from our basic outline to "purpose" a basic article layout. I would imagine certain headings will become more relevant as Lisa and I gather, learn, and write about paraptosis - again, just basic ideas to get started I am sure with information additions the article might look completely different. I also began writing sections/sentences (checking and rechecking for plagiarism etc.) as I came across potentially pertinent research. Additionally, I spent time with the citations. Currently the citations are "overdone" for certain resources but as more resources substantiate those authors conclusions I imagine this will no longer be the case. Lastly, I try to keep reminding myself to link to other articles - currently I am sure I have missed some, but I will check this in the future.


(from Lisa)

  • Uploaded and added a Creative Commons licensed image showing cells undergoing paraptosis.
  • Other contributions were prose: added information to history and cancer sections.

Article selection rationale[edit]

We have decided to create the paraptosis article. We chose this article as it is a topic we are both interested in and has sufficient information available for research. The only other article either of us had interest in was bacteriolysis, but we decided that it is too broad of a topic to create a satisfactory article in a limited time period. Paraptosis is a somewhat recently discovered form of cell death, morphologically distinct from apoptosis and necrosis. Creating a new page for a recent discovery is a great opportunity for us to both learn about emerging information but to also be able to provide this new information to the general public. Paraptosis has been found in programmed cell death pathways in both neurology and cancer, so it is possible that this article could become an important resource as more medical research is done.

In addition to Lisa's above comments, resources relating to paraptosis available to us through the JHU library seem well focused but not overly limited. Furthermore, as Lisa alluded to, Wikipedia articles currently available on related subjects, such as apoptosis, caspase, necrosis, and programmed cell death are well developed and would be great pathways to connect to. Lastly, if early medical research is any indication, paraptosis certainly seems to be a topic/page with lots of potential - both as a current project and in the future!

Initial article assessment from Lisawisa[edit]

5S ribosomal RNA[edit]

The article for 5S ribosomal RNA is considered a start article. There is some basic information provided, but a more explanation is needed for a reader to obtain a meaningful understanding. The main area that needs improvement is expanding the breadth of the article. References and citations are used, but more are needed to improve the quality of the article. The article does contain tagged images, as well as links to useful databases. These could be kept and expanded on. Possible references include[1] , [2] , and [3].

Bacteriolytic[edit]

An article for bacteriolytic has not yet been created. Basic information that should be in the article include a definition and examples of bacteriolytic agents/activity and their uses. A potential problem with this article is that it is a rather general topic, which could lead to very basic information about many areas, or very detailed information about only a few. References could include [4] , [5] , and [6].

Potential references[edit]

  1. ^ Szymański, M; Barciszewska, MZ; Erdmann, VA; Barciszewski, J (1 May 2003). "5 S rRNA: structure and interactions". The Biochemical journal. 371 (Pt 3): 641–51. PMID 12564956.
  2. ^ Ciganda, M; Williams, N (July–August 2011). "Eukaryotic 5S rRNA biogenesis". Wiley interdisciplinary reviews. RNA. 2 (4): 523–33. PMID 21957041.
  3. ^ Dechampesme, AM; Koroleva, O; Leger-Silvestre, I; Gas, N; Camier, S (28 June 1999). "Assembly of 5S ribosomal RNA is required at a specific step of the pre-rRNA processing pathway". The Journal of cell biology. 145 (7): 1369–80. PMID 10385518.
  4. ^ Schuch, R; Nelson, D; Fischetti, VA (22 August 2002). "A bacteriolytic agent that detects and kills Bacillus anthracis". Nature. 418 (6900): 884–9. PMID 12192412.
  5. ^ Linnebacher, M; Maletzki, C; Klier, U; Klar, E (April 2012). "Bacterial immunotherapy of gastrointestinal tumors". Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie. 397 (4): 557–68. PMID 22189906.
  6. ^ Satta, G; Varaldo, PE; Grazi, G; Fontana, R (April 1977). "Bacteriolytic activity in staphylococci". Infection and immunity. 16 (1): 37–42. PMID 873615.

Initial article assessment from Jhayes21[edit]

Paraptosis[edit]

This article has not been created yet. This article also does not have a commented on talk page. In order to begin to take this article to a B class, information such as a basic description of how this is a programmed cell death in the nonpoptotic form would be a start. Furthermore, elaboration on or even sections created about different types of inducers and perhaps a flow chart of pathway interactions would lay to foundation. Possible references could start to include [1] and [2]

Acetyltransferase[edit]

This article has a page. The talk section of this article does not appear to have been modified but any other editors. There is a diagram on the page, however the emphasis of this diagram should be the enzyme and not (what it is currently) a picture of what this enzyme transfers - perhaps this will make a great secondary picture. Currently on this page are references to specific types of acetyltransferases, these can be further elaborated on. Other information should be included such as chemical reactions taking place and mechanisms of action. There also doesn't appear to be any citations. Possible references could include [3] and [4]

Possible References[edit]

  1. ^ Sperandio, S; Poksay, K; de Belle, I; Lafuente, MJ; Liu, B; Nasir, J; Bredesen, DE (October 2004). "Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix". Cell death and differentiation. 11 (10): 1066–75. PMID 15195070.
  2. ^ Bröker, LE; Kruyt, FA; Giaccone, G (1 May 2005). "Cell death independent of caspases: a review". Clinical Cancer Research. 11 (9): 3155–62. PMID 15867207.
  3. ^ Friedmann, DR; Marmorstein, R (November 2013). "Structure and mechanism of non-histone protein acetyltransferase enzymes". The FEBS Journal. 280 (22): 5570–81. PMID 23742047.
  4. ^ Marmorstein, R (17 August 2001). "Structure of histone acetyltransferases". Journal of Molecular Biology. 311 (3): 433–44. PMID 11492997.
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