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Yusuke Nakamura (geneticist)

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Yusuke Nakamura
中村 祐輔
Born(1952-12-08)December 8, 1952
Osaka Prefecture, Japan
NationalityJapanese
Alma materOsaka University
Known forPersonalized medicine
Tumor suppressor gene APC
AwardsKeio Medical Science Prize (2000)
Scientific career
FieldsMolecular genetics
Cancer research
InstitutionsUniversity of Chicago
RIKEN
University of Tokyo
Japanese Foundation for Cancer Research
University of Utah

Yusuke Nakamura (中村 祐輔, Nakamura Yūsuke, born 8 December 1952) is a Japanese geneticist best known for identifying the tumor suppressor gene APC responsible for Familial Adenomatous Polyposis. In addition, he has been leading the research field of personalized medicine.[1]

Contribution

Nakamura identified Variable Number of Tandem Repeat (VNTR) markers in 1987[2] and APC in 1991.[3] He is one of the world's pioneers in applying genetic variations (VNTR and SNP markers) and whole genome sequencing and analysis. His outstanding contributions to medical science can be measured by his publication of nearly 1,200 scientific articles.[1]

Biography

Nakamura was born in Osaka on 8 December 1952.[4] He received his MD in 1977 and his PhD in 1984 from Osaka University. While working as a surgeon, he witnessed a 27 year old patient die of cancer, which affected him deeply.[5] In 1989, he became Head of the Biochemistry Department, at the Cancer Institute, Japanese Foundation for Cancer Research.[4] He was appointed as a professor at the Institute of Medical Science, University of Tokyo in 1994 and the Department of Medicine at the University of Chicago in 2012.[4]

From January to December 2011, Nakamura was Special Advisor to the Cabinet Secretary General, Office of Medical Innovation, Cabinet Secretariat, Government of Japan.[4]

Nakamura received the Keio Medical Science Prize in 2000 and the Tomizo Yoshida Award of the Japanese Cancer Association in 2002, and was elected as a member of the Association of American Physicians in 2011.[4]

Nakamura now works in his lab at the Pritzker School of Medicine in Chicago, which researches Oncoimmunogenomics, the genetic characterization of the immune system.[6]

References

  1. ^ a b "Yusuke Nakamura, Department of Medicine Faculty". Archived from the original on 2014-02-22. Retrieved 2014-02-12.
  2. ^ Nakamura, Y; Leppert, M; O'Connell, P; Wolff, R; Holm, T; Culver, M; Martin, C; Fujimoto, E; Hoff, M; Kumlin, E (1987). "Variable number of tandem repeat (VNTR) markers for human gene mapping". Science. 235 (4796): 1616–22. doi:10.1126/science.3029872. PMID 3029872.
  3. ^ Kinzler, K. W.; Nilbert, M. C.; Su, L. K.; Vogelstein, B; Bryan, T. M.; Levy, D. B.; Smith, K. J.; Preisinger, A. C.; Hedge, P; McKechnie, D (1991). "Identification of FAP locus genes from chromosome 5q21". Science. 253 (5020): 661–5. doi:10.1126/science.1651562. PMID 1651562.
  4. ^ a b c d e Yusuke Nakamura MD PhD
  5. ^ ""I would like to cure cancer"". Retrieved 2017-10-07.
  6. ^ "Nakamura Lab Research". Retrieved 2017-10-07.


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