Fetal thrombotic vasculopathy
Appearance
Fetal thrombotic vasculopathy | |
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Intermediate magnification micrograph of the placental disc showing a thrombosed fetal vein, as may be seen in fetal thrombotic vasculopathy. H&E stain. | |
Specialty | Pathology |
Fetal thrombotic vasculopathy is a chronic disorder characterized by thrombosis in the fetus leading to vascular obliteration and hypoperfusion.
It is associated with cerebral palsy and stillbirth.[1]
It is more common in women who have diabetes mellitus.
Diagnosis
[edit]It can be diagnosed by histomorphologic examination of the placenta and is characterized by fetal vessel thrombosis and clustered fibrotic chorionic villi without blood vessels.
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Low mag.
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High mag.
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Very high mag.
See also
[edit]References
[edit]- ^ Kraus, FT.; Acheen, VI. (Jul 1999). "Fetal thrombotic vasculopathy in the placenta: cerebral thrombi and infarcts, coagulopathies, and cerebral palsy". Hum Pathol. 30 (7): 759–69. doi:10.1016/s0046-8177(99)90136-3. PMID 10414494.