o-sec-Butylphenol

o-*sec*-Butylphenol
Names
	Preferred IUPAC name 2-(Butan-2-yl)phenol
	Other names 2-(1-Methylpropyl)phenol; 2-(sec-Butyl)phenol; 2-sec-Butylphenol; 2-(2-Butyl)phenol
Identifiers
CAS Number	89-72-5 ;
3D model (JSmol)	Interactive image;
ChemSpider	6718;
ECHA InfoCard	100.001.758
PubChem CID	6984;
RTECS number	SJ8920000;
UNII	025P24OTM5 ;
UN number	3145
CompTox Dashboard (EPA)	DTXSID2022331 ;
	InChI InChI=1S/C10H14O/c1-3-8(2)9-6-4-5-7-10(9)11/h4-8,11H,3H2,1-2H3 Key: NGFPWHGISWUQOI-UHFFFAOYSA-N; InChI=1/C10H14O/c1-3-8(2)9-6-4-5-7-10(9)11/h4-8,11H,3H2,1-2H3 Key: NGFPWHGISWUQOI-UHFFFAOYAN;
	SMILES CCC(C)C1=CC=CC=C1O;
Properties
Chemical formula	C10H14O
Molar mass	150.221 g·mol−1
Appearance	Colorless to amber-colored liquid or solid
Density	0.97724 g/cm3 (20 °C)
Melting point	16 °C; 61 °F; 289 K
Boiling point	230 °C (446 °F; 503 K)
Vapor pressure	4.74 Pa (25 °C)
Refractive index (nD)	1.5228 (20 °C)
Hazards
Flash point	107 °C; 225 °F; 380 K
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	>290 ppm/4 hours (inhalation, rat); 63 mg/kg (intraperitoneal, mouse); 60 mg/kg (intravenous, mouse); 600 mg/kg (oral, guinea pig); 320 mg/kg (oral, rat); 600 mg/kg (skin, guinea pig); 5560 mg/kg (skin, rabbit)
	NIOSH (US health exposure limits):
REL (Recommended)	5 ppm (30 mg/m3) [skin]
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

o-sec-Butylphenol is an industrial chemical used in dyeing and as a chemical intermediate. It is synthesized from phenol and 1-butene in an ortho-alkylation reaction.^[4] It is corrosive to the eyes, skin, and gastrointestinal tract.^[5]

References

^ ^a ^b ^c ^d Baird, Zachariah Steven; Uusi-Kyyny, Petri; Pokki, Juha-Pekka; Pedegert, Emilie; Alopaeus, Ville (6 Nov 2019). "Vapor Pressures, Densities, and PC-SAFT Parameters for 11 Bio-compounds". International Journal of Thermophysics. 40 (11): 102. doi:10.1007/s10765-019-2570-9.
^ ^a ^b ^c NIOSH Pocket Guide to Chemical Hazards. "#0084". National Institute for Occupational Safety and Health (NIOSH).
^ ^a ^b ^c ^d ^e ^f ^g "O-sec-butylphenol". Registry of Toxic Effects of Chemical Substances.
^ "O-sec-butylphenol". PubChem.
^ "O-sec-butylphenol". International Chemical Safety Cards.

[Baird2019-1] Baird, Zachariah Steven; Uusi-Kyyny, Petri; Pokki, Juha-Pekka; Pedegert, Emilie; Alopaeus, Ville (6 Nov 2019). "Vapor Pressures, Densities, and PC-SAFT Parameters for 11 Bio-compounds". International Journal of Thermophysics. 40 (11): 102. doi:10.1007/s10765-019-2570-9.

[NPG-2] NIOSH Pocket Guide to Chemical Hazards. "#0084". National Institute for Occupational Safety and Health (NIOSH).

[RTECS-3] ^ ^a ^b ^c ^d ^e ^f ^g "O-sec-butylphenol". Registry of Toxic Effects of Chemical Substances.

[4] "O-sec-butylphenol". PubChem.

[ICSC-5] "O-sec-butylphenol". International Chemical Safety Cards.

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