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Placental site nodule

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Placental site nodule
Micrograph of a placental site nodule (top of image). H&E stain.

A placental site nodule (PSN) is benign remnant from a previous pregnancy.[1]

Presentation

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They are typically asymptomatic and found incidentally.[1]

Pathology

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PSNs are intermediate trophoblastic remnants.

Diagnosis

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PSNs are diagnosed by examining the tissue under a microscope, usually obtained with a dilation and curettage.

Typically, they consist of pink (hyaline) material using the standard stain and contain few cells. Bizarre multinucleated cells may be present; however, there is no mitotic activity. The differential diagnosis includes (cervical) squamous cell carcinoma, gestational trophoblastic disease, and exaggerated placental site.

Prognosis

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PSN are benign. Once removed, they do not require any treatment and do not recur.

See also

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References

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  1. ^ a b Jacob, S.; Mohapatra, D. (2009). "Placental site nodule: a tumor-like trophoblastic lesion". Indian J Pathol Microbiol. 52 (2): 240–1. doi:10.4103/0377-4929.48931. PMID 19332926.
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