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  • Thumbnail for Penicillin
    Most penicillins in clinical use are synthesised by P. chrysogenum using deep tank fermentation and then purified. A number of natural penicillins have...
    98 KB (10,646 words) - 04:20, 2 September 2024
  • Thumbnail for Phenoxymethylpenicillin
    Behrens OK, Corse J (September 1948). "Biosynthesis of penicillins; biological precursors for benzylpenicillin (penicillin G)". The Journal of Biological Chemistry...
    15 KB (1,121 words) - 21:18, 3 July 2024
  • Thumbnail for Clavulanic acid
    bacteria that secrete β-lactamase, which otherwise inactivates most penicillins. In its most common preparations, potassium clavulanate (clavulanic acid...
    12 KB (1,139 words) - 09:16, 16 January 2024
  • Thumbnail for Beta-lactam antibiotics
    structure. Various transamidations lead to the different natural penicillins. The biosynthesis of cephems branch off at isopenicillin N by an oxidative ring...
    34 KB (3,704 words) - 13:07, 26 August 2024
  • and ampicillin acylase. This enzyme participates in penicillin and cephalosporin biosynthesis. As of late 2007, 34 structures have been solved for this...
    2 KB (186 words) - 15:18, 26 August 2023
  • N:acyl-CoA: acyltransferase. This enzyme participates in hydrophobic penicillins biosynthesis. Tobin MB, Fleming MD, Skatrud PL, Miller JR (1990). "Molecular...
    4 KB (361 words) - 14:36, 26 August 2023
  • Thumbnail for Penicillium chrysogenum
    (1994). "Expression of genes and processing of enzymes for the biosynthesis of penicillins and cephalosporins". Antonie van Leeuwenhoek. 65 (3): 227–43...
    12 KB (1,409 words) - 09:29, 12 February 2024
  • Thumbnail for Thienamycin
    are similar in structure to their antibiotic “cousins” the penicillins. Like penicillins, carbapenems contain a β-lactam ring (cyclic amide) fused to...
    11 KB (1,191 words) - 03:33, 4 March 2024
  • Thumbnail for Penicillium rubens
    Penicillium rubens (category Penicillins)
    for controlling the amount of penicillin synthesis; the more the gene is activated (expressed), the more the penicillins. P. rubens is the principal source...
    17 KB (1,973 words) - 01:32, 18 May 2024
  • Thumbnail for Fungus
    penicillins, a structurally related group of β-lactam antibiotics that are synthesized from small peptides. Although naturally occurring penicillins such...
    200 KB (19,172 words) - 18:21, 28 August 2024
  • (depending on isolate and subspecies) activity: occasionally penicillins including penicillin, ampicillin and ampicillin-sulbactam, amoxicillin and amoxicillin-clavulnate...
    30 KB (747 words) - 08:06, 6 January 2024
  • Thumbnail for Methicillin
    Methicillin (category Penicillins)
    Staphylococcus aureus to other penicillins facing β-lactam resistance; this role has now been passed on to other penicillins, namely cloxacillin, as well...
    8 KB (698 words) - 00:47, 29 April 2024
  • Thumbnail for Oxytetracycline
    shows the biosynthesis as described above, as well as an arrow-pushing mechanism of NADPH being used as the final cofactor in the biosynthesis of oxytetracycline...
    17 KB (1,684 words) - 15:43, 13 January 2024
  • Thumbnail for Vancomycin
    treatment of serious infections caused by susceptible organisms resistant to penicillins, such as methicillin-resistant S. aureus (MRSA) and multidrug-resistant...
    80 KB (7,968 words) - 07:30, 6 August 2024
  • Thumbnail for Beta-lactam
    structure of several antibiotic families, the principal ones being the penicillins, cephalosporins, carbapenems, and monobactams, which are, therefore,...
    11 KB (1,182 words) - 17:34, 24 January 2024
  • Thumbnail for Pseudopeptidoglycan
    September 2021). "Archaeal pseudomurein and bacterial murein cell wall biosynthesis share a common evolutionary ancestry". FEMS Microbes. 2: xtab012. doi:10...
    9 KB (1,042 words) - 10:57, 4 August 2024
  • Serine (section Biosynthesis)
    Serine (symbol Ser or S) is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+...
    24 KB (2,403 words) - 14:27, 10 June 2024
  • Thumbnail for Taurine
    is then oxidized to taurine as described above. A pathway for taurine biosynthesis from serine and sulfate is reported in microalgae, developing chicken...
    28 KB (2,903 words) - 13:45, 20 June 2024
  • Thumbnail for Cefazolin
    an allergy to penicillin may develop a cross sensitivity to cefazolin. Cefazolin inhibits cell wall biosynthesis by binding penicillin-binding proteins...
    16 KB (1,321 words) - 02:23, 31 March 2024
  • Thumbnail for Sultamicillin
    Sultamicillin (category Penicillins)
    other drugs are similar to other penicillins: allopurinol increases the risk for patients to develop rashes. Penicillins slow down the elimination of methotrexate...
    9 KB (744 words) - 01:12, 19 May 2024
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