Cochlear implant: Difference between revisions

Cochlear implant
Cochlear implant
	Cochlear implant
MedlinePlus	007203
	[edit on Wikidata]

Browse history interactively

← Previous edit Next edit →

Content deleted Content added

VisualWikitext

Inline

Revision as of 16:18, 9 December 2021

A cochlear implant (CI) is a surgically implanted neuroprosthesis that provides a person who has bilateral moderate-to-profound sensorineural hearing loss with sound perception and an opportunity with therapy for improved speech understanding in both quiet and noisy environments.^[1]^[2] A CI bypasses acoustic hearing by direct electrical stimulation of the auditory nerve.^[2] Through everyday listening and auditory training, both children and adults may learn to interpret those signals as speech and sound.^[3]^[4]^[5]

The implant has two main components. The outside component is generally worn behind the ear, but could also be attached to clothing, for example, in young children. This component, the sound processor, contains microphones, electronics that include digital signal processor (DSP) chips, battery, and a coil that transmits a signal to the implant across the skin. The inside component, the actual implant, has a coil to receive signals, electronics, and an array of electrodes which is placed into the cochlea, which stimulate the cochlear nerve.^[6]

The surgical procedure is performed under general anesthesia. Surgical risks are minimal but can include tinnitus, facial nerve bruising and dizziness.

From the early days of implants in the 1970s and the 1980s, speech perception via an implant has steadily increased. Many users of modern implants gain reasonable to good hearing and speech perception skills post-implantation, especially when combined with lipreading.^[7]^[8] One of the challenges that remain with these implants is that hearing and speech understanding skills after implantation show a wide range of variation across individual implant users. Factors such as age of implantation, parental involvement and education level, duration and cause of hearing loss, how the implant is situated in the cochlea, the overall health of the cochlear nerve, but also individual capabilities of re-learning are considered to contribute to this variation.^[9]^[10]^[11]

Despite providing the ability for hearing and oral speech communication to children and adults with severe to profound hearing loss, there is also controversy around the devices. Much of the strongest objection to cochlear implants has come from the Deaf community. For some in the Deaf community, cochlear implants are an affront to their culture, which as some view it, is a minority threatened by the hearing majority.^[12]

History

André Djourno and Charles Eyriès invented the original cochlear implant in 1957. This original design distributed stimulation using a single channel.^[13]

William House also invented a cochlear implant in 1961.^[14] In 1964, Blair Simmons and Robert J. White implanted a single-channel electrode in a patient's cochlea at Stanford University.^[15] However, research indicated that these single-channel cochlear implants were of limited usefulness because they cannot stimulate different areas of the cochlea at different times to allow differentiation between low and mid to high frequencies as required for detecting speech.^[16]

NASA engineer Adam Kissiah started working in the mid-1970s on what could become the modern cochlear implant. Kissiah used his knowledge learned while working as an electronics instrumentation engineer at NASA. This work took place over three years, when Kissiah would spend his lunch breaks and evenings in Kennedy's technical library, studying the impact of engineering principles on the inner ear. In 1977, NASA helped Kissiah obtain a patent for the cochlear implant; Kissiah later sold the patent rights.^[17]

The modern multi-channel cochlear implant was independently developed and commercialized by two separate teams—one led by Graeme Clark in Australia and another by Ingeborg Hochmair and her future husband, Erwin Hochmair in Austria, with the Hochmairs' device first implanted in a person in December 1977 and Clark's in August 1978.^[18]

Parts

Cochlear implants bypass most of the peripheral auditory system which receives sound and converts that sound into movements of hair cells in the cochlea; the deflection of stereocilia causes an influx of potassium ions into the hair cells, and the depolarisation in turn stimulates calcium influx, which increases release of the neurotransmitter, glutamate. Excitation of the cochlear nerve send signals to the brain, which creates the experience of sound. Instead, the devices pick up sound and digitize it, convert that digitized sound into electrical signals, and transmit those signals to electrodes embedded in the cochlea. The electrodes electrically stimulate the cochlear nerve, causing it to send signals to the brain.^[19]^[20]^[21]

There are several systems available, but generally they have the following components:^[19]^[21]

External:

one or more microphones that pick up sound from the environment
a speech processor which selectively filters sound to prioritize audible speech
a transmitter that sends power and the processed sound signals across the skin to the internal device by radio frequency transmission

Internal:

a receiver/stimulator, which receives signals from the speech processor and converts them into electric impulses
an electrode array embedded in the cochlea

A totally implantable cochlear implant (TICI) is currently in development. This new type of cochlear implant incorporates all the current external components of an audio processor into the internal implant. The lack of external components makes the implant invisible from the outside and also means it is less likely to suffer damage and breakages.^[22]

Assistive listening devices

Most modern cochlear implants can be used with a range of assistive listening devices (ALDs), which help people to hear better in challenging listening situations. These situations could include talking on the phone, watching TV or listening to a speaker or teacher. With an ALD, the sound from devices including mobile phones or from an external microphone is sent to the audio processor directly, rather than being picked up by the audio processor’s microphone. This direct transmission improves the sound quality for the user, making it easier to talk on the phone or stream music.

ALDs come in many forms, such as neckloops,^[23] pens,^[24] and specialist battery pack covers.^[25] Modern ALDs are usually able to receive sound from any Bluetooth device, including phones and computers, before transmitting it wirelessly to the audio processor. Most cochlear implants are also compatible with older ALD technology, such as a telecoil.^[26]

Surgical procedure

Traditional surgical technique

Implantation of children and adults can be done safely with few surgical complications and most individuals will undergo outpatient surgery.^[27]^[28]

The surgical procedure most often used to implant the device is called mastoidectomy with facial recess approach (MFRA).^[21]

The procedure is usually done under general anesthesia. Complications of the procedure are rare, but include mastoiditis, otitis media (acute or with effusion), shifting of the implanted device requiring a second procedure, damage to the facial nerve, damage to the chorda tympani, and wound infections.^[29]

The rate of complications is about 12% for minor complications and 3% for major complications; major complications include infections, facial paralysis, and device failure. To avoid the risk of bacterial meningitis, which while low is about thirty times as high compared to people who don't undergo CI procedures, the FDA recommends vaccination prior to the procedure. The rate of transient facial nerve palsy is estimated to be approximately 1%. Device failure requiring reimplantation is estimated to occur 2.5–6% of the time. Up to one-third of people experience disequilibrium, vertigo, or vestibular weakness lasting more than one week after the procedure; in people under 70 these symptoms generally resolve over weeks to months, but in people over 70 the problems tend to persist.^[21]

In the past cochlear implants were only approved for people who were deaf in both ears; as of 2014^[update] a cochlear implant had been used experimentally in some people who had acquired deafness in one ear after they had learned how to speak, and none who were deaf in one ear from birth; clinical studies as of 2014^[update] had been too small to draw generalizations.^[30]

Alternative surgical technique

Other approaches, such as going through the suprameatal triangle, are used. A systematic literature review published in 2016 found that studies comparing the two approaches were generally small, not randomized, and retrospective so were not useful for making generalizations; it is not known which approach is safer or more effective.^[29]

Endoscopic cochlear implantation

With the increased utilization of endoscopic ear surgery as popularized by professor Tarabichi, there have been multiple published reports on the use of endsocopic technique in cochlear impant surgery.^[31] However, this has been motivated by marketing and there is clear indication of increased morbidity associated with this technique as reported by the pioneer of endoscopic ear surgery.^[32]

Outcomes

Cochlear implant outcomes can be measured using speech recognition ability and functional improvements measured using patient reported outcome measures.^[33]^[34] While the degree of improvement after cochlear plantation may vary, the majority of patients who receive cochlear implants demonstrate a significant improvement in speech recognition ability compared to their preoperative condition.^[33]

Meta-analyses from 2017 and 2018 of the literature showed that CI users have large improvements in quality of life after cochlear implantation.^[35]^[36] This improvement occurs in many different facets of life that extends beyond communication including improved ability to engage in social activities; decreased mental effort from listening; and improved environmental sound awareness.^[37]^[38]^[34] Deaf adolescents with cochlear implants attending mainstream educational settings report high levels of scholastic self-esteem, friendship self-esteem, and global self-esteem.^[39] They also tend to hold mostly positive attitudes towards their cochlear implants,^[40] and as a part of their identity, a majority either do "not really think about" their hearing loss, or are "proud of it." ^[41]

Efficacy

A 2019 study found that bilateral cochlear implantation was widely regarded as the most beneficial hearing intervention for acceptable candidates, although it is more likely to be performed and reimbursed in children than adults. The study also found that the efficacy of bilateral implantation could be improved by enhancing communication between the two implants and by developing sound coding strategies specifically for bilateral users.^[42]

Early research reviews found that the ability to communicate in spoken language was better the earlier the implantation was performed. The reviews also found that, overall, while cochlear implants provide open set speech understanding for the majority of implanted profoundly hearing-impaired children, and that it was not possible to accurately predict the specific outcome of the given implanted child.^[43]^[44]^[45] Research since then has reported long-term socio-economic benefits for children as well as audiological outcomes including improved sound localization and speech perception.^[46] A consensus statement from the European Bilateral Pediatric Cochlear Implant Forum also confirmed the importance of bilateral cochlear implantation in children.^[47] In adults, new research shows that bilateral implantation can improve quality of life and speech intelligibility in quiet and noise.^[48]

A 2015 review examined whether CI implantation to treat people with bilateral hearing loss had any effect on tinnitus. This review found the quality of evidence to be poor and the results variable: overall total tinnitus suppression rates for patients who had tinnitus prior to surgery varied from 8% to 45% of people who received CI; decrease of tinnitus was seen in 25% to 72%, of people; for 0% to 36% of the people there was no change; increase of tinnitus occurred in between 0% to 25% of patients; and, in between 0 and 10% of cases, people who did not have tinnitus before the procedure, got it.^[49] Further research found that the electrical stimulation of the CI is at least partly responsible for the general reduction in symptoms. A 2019 study found that although tinnitus suppression in patients with CIs is multifactorial, simply having the CI switched on without any audiological input (while standing alone in a soundproof booth) reduced the symptoms of tinnitus. This would suggest that it is the electrical stimulation that explains the decrease in tinnitus symptoms for many patients, and not only the increased access to sound.^[50]

A 2015 literature review on the use of CI for people with auditory neuropathy spectrum disorder found that, as of that date, description and diagnosis of the condition was too heterogeneous to make clear claims about whether CI is a safe and effective way to manage it.^[51]

The data for cochlear implant outcomes in older adults differs. A 2016 research study found that age at implantation was highly correlated with post-operative speech understanding performance for various test measures. In this study, people who were implanted at age 65 or older performed significantly worse on speech perception testing in quiet and in noisy conditions compared to younger CI users.^[52] Other studies have shown different outcomes, with some reporting that adults implanted at the age of 65 and older showed audiological and speech discrimination outcomes similar to younger adults.^[53]

The effects of aging on central auditory processing abilities are thought to play an important role in impacting an individual's speech perception with a cochlear implant. The Lancet reported that untreated hearing loss in adults is the number one modifiable risk factor for dementia.^[54] In 2017, a study also reported that adults using a cochlear implant had significantly improved cognitive outcomes including working memory, reaction time, and cognitive flexibility compared to people who were waiting to receive a cochlear implant.^[55]

Prolonged duration of deafness is another factor that is thought to have a negative impact on overall speech understanding outcomes for CI users. However, a study found no statistical difference in the speech understanding abilities of CI patients over 65 who had been hearing impaired for 30 years or more prior to implantation.^[52] In general, outcomes for CI patients are dependent upon the individual's level of motivation, expectations, exposure to speech stimuli and consistent participation in aural rehabilitation programs.

A 2016 systematic review of CI for people with unilateral hearing loss (UHL) found that of the studies conducted and published, none were randomized, only one evaluated a control group, and no study was blinded. After eliminating multiple uses of the same subjects, the authors found that 137 people with UHL had received a CI.^[56] While acknowledging the weakness of the data, the authors found that CI in people with UHL improves sound localization compared with other treatments in people who lost hearing after they learned to speak; in the one study that examined this, CI did improve sound localization in people with UHL who lost hearing before learning to speak.^[56] It appeared to improve speech perception and to reduce tinnitus.^[56]

In terms of quality of life, several studies have shown that cochlear implants are beneficial in many aspects of quality of life, including communication improvements and positive effects on social, emotional, psychological and physical well-being. A 2017 narrative review also concluded that the quality of life scores of children using cochlear implants were comparable to those of children without hearing loss. Studies involving adults of all ages reported significant improvement in QoL after implantation when compared to adults with hearing aids. This was often independent of audiological performance.^[57]

Society and culture

Usage

As of October 2010,^[update] approximately 188,000 individuals had been fitted with cochlear implants.^[58] As of December 2012,^[update] the same publication cited approximately 324,000 cochlear implant devices having been surgically implanted. In the U.S., roughly 58,000 devices were implanted in adults and 38,000 in children.^[20] As of 2016,^[update] the Ear Foundation in the United Kingdom, estimates the number of cochlear implant recipients in the world to be about 600,000.^[59]

Cost

In the United States, the overall cost of getting cochlear implants was about $100,000 as of 2017.^[update]^[60] Some or all of this may be covered by health insurance. In the United Kingdom, the NHS covers cochlear implants in full, as does Medicare in Australia, and the Department of Health^[61] in Ireland, Seguridad Social in Spain, Sécurité Sociale in France^[62] and Israel, and the Ministry of Health or ACC (depending on the cause of deafness) in New Zealand. According to the US National Institute on Deafness and Other Communication Disorders, the estimated total cost is $60,000 per person implanted.^{[citation needed]}

A study by Johns Hopkins University determined that for a three-year-old child who receives them, cochlear implants can save $30,000 to $50,000 in special-education costs for elementary and secondary schools as the child is more likely to be mainstreamed in school and thus use fewer support services than similarly deaf children.^[63]

Public Health

6.1% of the world population live with hearing loss, and it is predicted that by 2050, more than 900 million people around the globe will have a disabling hearing loss.^[64] According to a WHO report, unaddressed hearing loss costs the world 980 billion dollars annually. Particularly hard hit are the healthcare and educational sectors, as well as societal costs. 53% of these costs are attributable to low- and middle-income countries.^[65]

The WHO reports that cochlear implants have been shown to be a cost-effective way to mitigate the challenges of hearing loss. In a low-to-middle-income setting, every dollar invested in unilateral cochlear implants has a return on investment of 1.46 dollars. This rises to a return on investment of 4.09 dollars in an upper-middle-income setting. A study in Colombia assessed the lifetime investments made in 68 children who received cochlear implants at an early age. Taking into account the cost of the device and any other medical costs, follow-up, speech therapy, batteries and travel, each child required an average investment of US$ 99 000 over the course of their life (assuming a life span of 78 years for women and 72 years for men). The study concluded that for every dollar invested in rehabilitation of a child with a cochlear implant, there was a return on investment of US$ 2.07.^[65]

Manufacturers

As of 2013,^[update] the three cochlear implant devices approved for use in the US were manufactured by Cochlear Limited (Australia), Advanced Bionics (a division of Sonova) and MED-EL (Austria). In Europe, Africa, Asia, South America, and Canada, an additional device manufactured by Neurelec (France, a division of William Demant) was available. A device made by Nurotron (China) was also available in some parts of the world. Each manufacturer has adapted some of the successful innovations of the other companies to its own devices. There is no consensus that any one of these implants is superior to the others. Users of all devices report a wide range of performance after implantation.^{[citation needed]}

Criticism and controversy

Much of the strongest objection to cochlear implants has come from within the Deaf community, some of whom are pre-lingually deaf people whose first language is a sign language. For some in the Deaf community, cochlear implants are an affront to their culture, which, as they view it, is a minority threatened by the hearing majority.^[12] This is an old problem for the Deaf community, going back as far as the 18th century with the argument of manualism vs. oralism. This is consistent with medicalisation and the standardisation of the "normal" body in the 19th century when differences between normal and abnormal began to be debated.^[66] It is important to consider the sociocultural context, particularly in regards to the Deaf community, which has its own unique language and culture.^[67] This accounts for the cochlear implant being seen as an affront to their culture, as many do not believe that deafness is something that needs to be cured. However, it has also been argued that this does not necessarily have to be the case: the cochlear implant can act as a tool deaf people can use to access the "hearing world" without losing their Deaf identity.^[67]

Cochlear implants for congenitally deaf children are most effective when implanted at a young age.^[68] Evidence shows that Deaf children of Deaf parents (or with fluent signers as daily caregivers) learn signed language as effectively as hearing peers. Some Deaf-community advocates recommend that all Deaf children should learn sign language from birth,^[69] but more than 90% of deaf children are born to hearing parents. Since it takes years to become fluent in sign language, deaf children who grow up without amplification such as hearing aids or cochlear implants will not have daily access to fluent language models in households without fluent signers.

Critics of cochlear implants from Deaf cultures also assert that the cochlear implant and the subsequent therapy often become the focus of the child's identity at the expense of language acquisition and ease of communication in sign language and Deaf identity. They believe that measuring a child's success only by their mastery of speech will lead to a poor self-image as "disabled" (because the implants do not produce normal hearing) rather than having the healthy self-concept of a proudly Deaf person.^[70] However, these assertions are not supported by research. The first children to receive cochlear implants as infants are only in their 20s (as of 2020), and anecdotal evidence points to a high level of satisfaction in this cohort, most of whom don't consider their deafness their primary identity.^[39]^[40]^[71]

Children with cochlear implants are most likely to be educated with listening and spoken language, without sign language and are often not educated with other Deaf children who use sign language.^[72] Cochlear implants have been one of the technological and social factors implicated in the decline of sign languages in the developed world.^[73] Some Deaf activists have labeled the widespread implantation of children as a cultural genocide.^[74]

As the trend for cochlear implants in children grows, Deaf-community advocates have tried to counter the "either or" formulation of oralism vs. manualism with a "both and" or "bilingual-bicultural"^[75] approach; some schools are now successfully integrating cochlear implants with sign language in their educational programs.^[76] However, there is no clinical evidence suggesting that sign language supports the development of spoken language, while there is significant clinical evidence suggesting that deaf children (of hearing parents) who use no sign language or very little sign language develop better spoken language skills than those children who use both sign and speech.^[77]

References

^ "NCD - Cochlear Implantation (50.3)". www.cms.gov. Retrieved 2021-11-22.
^ ^a ^b "Cochlear Implants". NIDCD. Retrieved 2021-11-22.
^ Rayes H, Al-Malky G, Vickers D (May 2019). "Systematic Review of Auditory Training in Pediatric Cochlear Implant Recipients". Journal of Speech, Language, and Hearing Research. 62 (5): 1574–1593. doi:10.1044/2019_JSLHR-H-18-0252. PMID 31039327. S2CID 141503740.
^ Henshaw H, Ferguson MA (2013-05-10). "Efficacy of individual computer-based auditory training for people with hearing loss: a systematic review of the evidence". PloS One. 8 (5): e62836. Bibcode:2013PLoSO...862836H. doi:10.1371/journal.pone.0062836. PMC 3651281. PMID 23675431.
^ Sweetow R, Palmer CV (July 2005). "Efficacy of individual auditory training in adults: a systematic review of the evidence". Journal of the American Academy of Audiology. 16 (7): 494–504. doi:10.3766/jaaa.16.7.9. PMID 16295236.
^ Naples JG, Ruckenstein MJ (February 2020). "Cochlear Implant". Otolaryngologic Clinics of North America. 53 (1): 87–102. doi:10.1016/j.otc.2019.09.004. PMID 31677740. S2CID 207890377.
^ Clark GM (April 2015). "The multi-channel cochlear implant: multi-disciplinary development of electrical stimulation of the cochlea and the resulting clinical benefit". Hearing Research. 322: 4–13. doi:10.1016/j.heares.2014.08.002. PMID 25159273.
^ Shannon RV (February 2012). "Advances in auditory prostheses". Current Opinion in Neurology. 25 (1): 61–66. doi:10.1097/WCO.0b013e32834ef878. PMC 4123811. PMID 22157109.
^ Blamey P, Artieres F, Başkent D, Bergeron F, Beynon A, Burke E, et al. (2013). "Factors affecting auditory performance of postlinguistically deaf adults using cochlear implants: an update with 2251 patients". Audiology & Neuro-Otology. 18 (1): 36–47. doi:10.1159/000343189. PMID 23095305. S2CID 4668675.
^ Başkent D, Gaudrain E, Tamati TN, Wagner A (2016). Cacace AT, de Kleine E, Holt AG, van Dijk P (eds.). Perception and psychoacoustics of speech in cochlear implant users, in Scientific Foundations of Audiology: Perspectives from Physics, Biology, Modeling, and Medicine,. San Diego, CA, USA: Plural Publishing, Inc. pp. 285–319.
^ Pisoni DB, Kronenberger WG, Harris MS, Moberly AC (December 2017). "Three challenges for future research on cochlear implants". World Journal of Otorhinolaryngology - Head and Neck Surgery. 3 (4): 240–254. doi:10.1016/j.wjorl.2017.12.010. PMC 5956139. PMID 29780970.
^ ^a ^b "The Cochlear Implant Controversy, Issues And Debates". CBS News. NEW YORK. September 4, 2001. Retrieved 2021-05-08.
^ Svirsky M (2017). "Cochlear implants and electronic hearing". Physics Today. 70 (8): 52–58. Bibcode:2017PhT....70h..52S. doi:10.1063/PT.3.3661. ISSN 0031-9228.
^ Martin D (December 15, 2012). "Dr. William F. House, Inventor of Pioneering Ear-Implant Device, Dies at 89". The New York Times. Retrieved 2012-12-16.
^ Mudry A, Mills M (May 2013). "The early history of the cochlear implant: a retrospective". JAMA Otolaryngology-- Head & Neck Surgery. 139 (5): 446–453. doi:10.1001/jamaoto.2013.293. PMID 23681026.
^ Clark G (2009). "The multi-channel cochlear implant: past, present and future perspectives". Cochlear Implants International. 10 (Suppl 1): 2–13. doi:10.1179/cim.2009.10.Supplement-1.2. PMID 19127562. S2CID 30532987.
^ NASA (2003). NASA space station. Washington, DC: U.S. Government Printing. Archived from the original on 2003-10-18.
^ "2013 Lasker~DeBakey Clinical Medical Research Award: Modern cochlear implant". The Lasker Foundation. Retrieved 14 July 2017.
^ ^a ^b Roche JP, Hansen MR (December 2015). "On the Horizon: Cochlear Implant Technology". Otolaryngologic Clinics of North America. 48 (6): 1097–1116. doi:10.1016/j.otc.2015.07.009. PMC 4641792. PMID 26443490.
^ ^a ^b NIH Publication No. 11-4798 (2013-11-01). "Cochlear Implants". National Institute on Deafness and Other Communication Disorders. Retrieved February 18, 2016.{{cite web}}: CS1 maint: numeric names: authors list (link)
^ ^a ^b ^c ^d Yawn R, Hunter JB, Sweeney AD, Bennett ML (2015). "Cochlear implantation: a biomechanical prosthesis for hearing loss". F1000Prime Reports. 7: 45. doi:10.12703/P7-45. PMC 4447036. PMID 26097718.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ Cohen N (April 2007). "The totally implantable cochlear implant". Ear and Hearing. 28 (2 Suppl): 100S–101S. doi:10.1097/AUD.0b013e31803150f4. PMID 17496658. S2CID 38696317.
^ "Induction Neckloops - Bluetooth Neckloop". ADCO Hearing Products. Retrieved 2021-12-09.
^ "Phonak Roger Pen". www.ihear.co.uk. Retrieved 2021-12-09.
^ "AudioStream - Connect Your MED-EL Cochlear Implant". www.medel.com. Retrieved 2021-12-09.
^ "Using the telephone". cochlear implant HELP. 2012-03-29. Retrieved 2021-12-09.
^ Hoff S, Ryan M, Thomas D, Tournis E, Kenny H, Hajduk J, Young NM (April 2019). "Safety and Effectiveness of Cochlear Implantation of Young Children, Including Those With Complicating Conditions". Otology & Neurotology. 40 (4): 454–463. doi:10.1097/MAO.0000000000002156. PMID 30870355.
^ "Hearing aids vs cohclear implants: What's the difference?". www.medicalnewstoday.com. 2021-05-28. Retrieved 2021-12-01.
^ ^a ^b Bruijnzeel H, Draaisma K, van Grootel R, Stegeman I, Topsakal V, Grolman W (April 2016). "Systematic Review on Surgical Outcomes and Hearing Preservation for Cochlear Implantation in Children and Adults". Otolaryngology--Head and Neck Surgery. 154 (4): 586–596. doi:10.1177/0194599815627146. PMID 26884363. S2CID 25594951.
^ Tokita J, Dunn C, Hansen MR (October 2014). "Cochlear implantation and single-sided deafness". Current Opinion in Otolaryngology & Head and Neck Surgery. 22 (5): 353–358. doi:10.1097/moo.0000000000000080. PMC 4185341. PMID 25050566.
^ Rajan P, Teh HM, Prepageran N, Kamalden TI, Tang P (2017-12-01). "Endoscopic Cochlear Implant: Literature Review and Current Status". Current Otorhinolaryngology Reports. 5 (4): 268–274. doi:10.1007/s40136-017-0164-2. ISSN 2167-583X. S2CID 80330932.
^ Tarabichi M, Nazhat O, Kassouma J, Najmi M (March 2016). "Endoscopic cochlear implantation: Call for caution". The Laryngoscope. 126 (3): 689–692. doi:10.1002/lary.25462. PMID 26154143. S2CID 24799811.
^ ^a ^b Dornhoffer JR, Reddy P, Meyer TA, Schvartz-Leyzac KC, Dubno JR, McRackan TR (March 2021). "Individual Differences in Speech Recognition Changes After Cochlear Implantation". JAMA Otolaryngology-- Head & Neck Surgery. 147 (3): 280–286. doi:10.1001/jamaoto.2020.5094. PMID 33410869.
^ ^a ^b McRackan TR, Velozo CA, Holcomb MA, Camposeo EL, Hatch JL, Meyer TA, et al. (October 2017). "Use of Adult Patient Focus Groups to Develop the Initial Item Bank for a Cochlear Implant Quality-of-Life Instrument". JAMA Otolaryngology-- Head & Neck Surgery. 143 (10): 975–982. doi:10.1001/jamaoto.2017.1182. PMC 5710256. PMID 28772297.
^ McRackan TR, Bauschard M, Hatch JL, Franko-Tobin E, Droghini HR, Nguyen SA, Dubno JR (April 2018). "Meta-analysis of quality-of-life improvement after cochlear implantation and associations with speech recognition abilities". The Laryngoscope. 128 (4): 982–990. doi:10.1002/lary.26738. PMID 28731538.
^ McRackan TR, Bauschard M, Hatch JL, Franko-Tobin E, Droghini HR, Velozo CA, et al. (January 2018). "Meta-analysis of Cochlear Implantation Outcomes Evaluated With General Health-related Patient-reported Outcome Measures". Otology & Neurotology. 39 (1): 29–36. doi:10.1097/mao.0000000000001620. PMID 29227446.
^ Hughes SE, Hutchings HA, Rapport FL, McMahon CM, Boisvert I (September 2018). "Social Connectedness and Perceived Listening Effort in Adult Cochlear Implant Users: A Grounded Theory to Establish Content Validity for a New Patient-Reported Outcome Measure". Ear and Hearing. 39 (5): 922–934. doi:10.1097/AUD.0000000000000553. PMID 29424766.
^ McRackan TR, Hand BN, Velozo CA, Dubno JR (September 2019). "Cochlear Implant Quality of Life (CIQOL): Development of a Profile Instrument (CIQOL-35 Profile) and a Global Measure (CIQOL-10 Global)". Journal of Speech, Language, and Hearing Research. 62 (9): 3554–3563. doi:10.1044/2019_JSLHR-H-19-0142. PMC 6808347. PMID 31479616.
^ ^a ^b Leigh, I. W.; Maxwell-McCaw, D.; Bat-Chava, Y.; Christiansen, J. B. (2008-07-16). "Correlates of Psychosocial Adjustment in Deaf Adolescents With and Without Cochlear Implants: A Preliminary Investigation". Journal of Deaf Studies and Deaf Education. 14 (2): 244–259. doi:10.1093/deafed/enn038. ISSN 1081-4159.
^ ^a ^b Most, Tova; Wiesel, Amatzia; Blitzer, Tamar (June 2007). "Identity and Attitudes towards Cochlear Implant Among Deaf and Hard of Hearing Adolescents". Deafness & Education International. 9 (2): 68–82. doi:10.1179/146431507790560002. ISSN 1464-3154.
^ Dammeyer, Jesper; Chapman, Madeleine; Marschark, Marc (2018). "Experience of Hearing Loss, Communication, Social Participation, and Psychological Well-Being Among Adolescents With Cochlear Implants". American Annals of the Deaf. 163 (4): 424–439. ISSN 0002-726X.
^ Rak, Kristen; Völker, Johannes; Schendzielorz, Philipp; Shehata-Dieler, Wafaa; Radeloff, Andreas; Hagen, Rudolf (2019-03). "Bilateral cochlear implantation is regarded as very beneficial: results from a worldwide survey by online questionnaire". European archives of oto-rhino-laryngology: official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS): affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 276 (3): 679–683. doi:10.1007/s00405-018-05271-x. ISSN 1434-4726. PMID 30617425. {{cite journal}}: Check date values in: |date= (help)
^ Kral A, O'Donoghue GM (October 2010). "Profound deafness in childhood". The New England Journal of Medicine. 363 (15): 1438–1450. doi:10.1056/NEJMra0911225. PMID 20925546. S2CID 13639137.
^ Niparko JK, Tobey EA, Thal DJ, Eisenberg LS, Wang NY, Quittner AL, Fink NE (April 2010). "Spoken language development in children following cochlear implantation". Jama. 303 (15): 1498–1506. doi:10.1001/jama.2010.451. PMC 3073449. PMID 20407059.
^ Ganek H, McConkey Robbins A, Niparko JK (February 2012). "Language outcomes after cochlear implantation". Otolaryngologic Clinics of North America. 45 (1): 173–185. doi:10.1016/j.otc.2011.08.024. PMID 22115689.
^ Cheng, Li-Jen; Soon, Swee Sung; Wu, David Bin-Chia; Ju, Hong; Ng, Kwong (2019-08-15). "Cost-effectiveness analysis of bilateral cochlear implants for children with severe-to-profound sensorineural hearing loss in both ears in Singapore". PLOS ONE. 14 (8): e0220439. doi:10.1371/journal.pone.0220439. ISSN 1932-6203. PMC 6695111. PMID 31415595.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
^ Ramsden, James D.; Gordon, Karen; Aschendorff, Antje; Borucki, Lukasz; Bunne, Marie; Burdo, Sandro; Garabedian, Noel; Grolman, Wilko; Irving, Richard; Lesinski-Schiedat, Anke; Loundon, Natalie (2012-06). "European Bilateral Pediatric Cochlear Implant Forum Consensus Statement". Otology & Neurotology. 33 (4): 561–565. doi:10.1097/MAO.0b013e3182536ae2. ISSN 1531-7129. {{cite journal}}: Check date values in: |date= (help)
^ Sivonen, Ville; Sinkkonen, Saku T.; Willberg, Tytti; Lamminmäki, Satu; Jääskelä-Saari, Hilkka; Aarnisalo, Antti A.; Dietz, Aarno (2021-01). "Improvements in Hearing and in Quality of Life after Sequential Bilateral Cochlear Implantation in a Consecutive Sample of Adult Patients with Severe-to-Profound Hearing Loss". Journal of Clinical Medicine. 10 (11): 2394. doi:10.3390/jcm10112394. {{cite journal}}: Check date values in: |date= (help)CS1 maint: unflagged free DOI (link)
^ Ramakers GG, van Zon A, Stegeman I, Grolman W (November 2015). "The effect of cochlear implantation on tinnitus in patients with bilateral hearing loss: A systematic review". The Laryngoscope. 125 (11): 2584–2592. doi:10.1002/lary.25370. PMID 26153087. S2CID 19088970.
^ Mallen, Jonathan R.; Chiu, Jerlon; Marquis, Hillary; Ottochian, Amanda; Perez, Erin; Kuo, Chia-Ling; Otto, Steve; Ryan, Tessa; Roberts, Daniel S. (2020). "Quantifying tinnitus suppression in cochlear implantation using tinnitus interval-limited tracking". The Laryngoscope. 130 (8): 2047–2052. doi:10.1002/lary.28414. ISSN 1531-4995.
^ Harrison RV, Gordon KA, Papsin BC, Negandhi J, James AL (December 2015). "Auditory neuropathy spectrum disorder (ANSD) and cochlear implantation". International Journal of Pediatric Otorhinolaryngology. 79 (12): 1980–1987. doi:10.1016/j.ijporl.2015.10.006. PMID 26545793.
^ ^a ^b Beyea JA, McMullen KP, Harris MS, Houston DM, Martin JM, Bolster VA, et al. (October 2016). "Cochlear Implants in Adults: Effects of Age and Duration of Deafness on Speech Recognition". Otology & Neurotology. 37 (9): 1238–1245. doi:10.1097/MAO.0000000000001162. PMID 27466894. S2CID 10143665.
^ Schafer, Erin C.; Miller, Sharon; Manning, Jacy; Zhang, Qi; Lavi, Alexandra; Bodish, Emily; Fuentes, Andrea; De, Blaey Eric (2021-09-10). "Meta-Analysis of Speech Recognition Outcomes in Younger and Older Adults With Cochlear Implants". American Journal of Audiology. 30 (3): 481–496. doi:10.1044/2021_AJA-20-00141.
^ Livingston, Gill; Huntley, Jonathan; Sommerlad, Andrew; Ames, David; Ballard, Clive; Banerjee, Sube; Brayne, Carol; Burns, Alistair; Cohen-Mansfield, Jiska; Cooper, Claudia; Costafreda, Sergi G. (2020-08-08). "Dementia prevention, intervention, and care: 2020 report of the Lancet Commission". The Lancet. 396 (10248): 413–446. doi:10.1016/S0140-6736(20)30367-6. ISSN 0140-6736. PMID 32738937.
^ Speers, Amanda; George, Asha; Toner, Joseph (2015-01-01). "An aging concern: A retrospective study comparing the audiological and speech outcome measures along with the surgical and quality-of-life outcomes in a group of geriatric patients with those of an adult control group". Cochlear Implants International. 16 (sup1): S3–S5. doi:10.1179/1467010014Z.000000000222. ISSN 1467-0100. PMID 25614263.
^ ^a ^b ^c Cabral Junior F, Pinna MH, Alves RD, Malerbi AF, Bento RF (January 2016). "Cochlear Implantation and Single-sided Deafness: A Systematic Review of the Literature". International Archives of Otorhinolaryngology. 20 (1): 69–75. doi:10.1055/s-0035-1559586. PMC 4687988. PMID 26722349.
^ Crowson, Matthew G.; Semenov, Yevgeniy R.; Tucci, Debara L.; Niparko, John K. (2017). "Quality of Life and Cost-Effectiveness of Cochlear Implants: A Narrative Review". Audiology and Neurotology. 22 (4–5): 236–258. doi:10.1159/000481767. ISSN 1420-3030. PMID 29262414.
^ "NIH Fact Sheets - Cochlear Implants". report.nih.gov. Archived from the original on 2011-10-22. Retrieved 2018-09-14.
^ "Cochlear Implant Information Sheet". The Ear Foundation. Archived from the original on 2017-07-11. Retrieved 2018-09-14.
^ "Cochlear Implants". American Academy of Otolaryngology–Head and Neck Surgery. 21 April 2014. Archived from the original on 24 August 2017. Retrieved 12 May 2017.
^ "Beaumont Hospital - Cochlear Implant - How to Refer".
^ "Coût de l'implant cochléaire". CISIC.fr (in French). Centre d'Information sur la Surdité et l'Implant Cochléaire.
^ Williams JM (2000-05-05). "Do Health-Care Providers Have to Pay for Assistive Tech?". Business Week. Retrieved 2009-10-25.
^ D'Haese, Patrick S. C.; Van Rompaey, Vincent; De Bodt, Marc; Van de Heyning, Paul (2019). "Severe Hearing Loss in the Aging Population Poses a Global Public Health Challenge. How Can We Better Realize the Benefits of Cochlear Implantation to Mitigate This Crisis?". Frontiers in Public Health. 7: 227. doi:10.3389/fpubh.2019.00227. ISSN 2296-2565.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ ^a ^b "World report on hearing". www.who.int. Retrieved 2021-12-09.
^ Lock, M. and Nguyen, V-K., An Anthropology of Biomedicine, Oxford, Wiley-Blackwell, 2010.^{[page needed]}
^ ^a ^b Power D (2005). "Models of deafness: cochlear implants in the Australian daily press". Journal of Deaf Studies and Deaf Education. 10 (4): 451–459. doi:10.1093/deafed/eni042. PMID 16000690.
^ Oginni P (2009-11-16). "UCI Research with Cochlear Implants No Longer Falling on Deaf Ears". New University. Retrieved 2009-11-18.
^ Hall ML, Hall WC, Caselli NK (2019). "Deaf children need language, not (Just) speech". First Language. 39 (4): 367–395. doi:10.1177/0142723719834102. S2CID 140083091.
^ NAD Cochlear Implant Committee. "Cochlear Implants". Archived from the original on 2007-02-20.
^ Hicks K (2016-08-05). "We Are Not Language Deprived".
^ Ringo A (August 9, 2013). "Understanding Deafness: Not Everyone Wants to Be 'Fixed'". The Atlantic.
^ Johnston T (2004). "W(h)ither the deaf community? Population, genetics, and the future of Australian sign language". American Annals of the Deaf. 148 (5): 358–375. doi:10.1353/aad.2004.0004. PMID 15132016. S2CID 21638387.
^ Christiansen JB, Leigh IW, Spencer PE, Lucker JR (2001). Cochlear implants in children : ethics and choices ([Online-Ausg.] ed.). Washington, D.C.: Gallaudet University Press. pp. 304–305. ISBN 9781563681165.
^ De Vera N, Dharer Y. "Bilingual-Bicultural Education of Deaf/Hard-of- Hearing Children". deafed. Retrieved 9 February 2020.
^ Denworth L (April 25, 2014). "Science Gave My Son the Gift of Sound". Time.
^ Geers A (2017-07-01). "Early Sign Language Exposure and Cochlear Implantation Benefits".
^ 3D microscaffold cochlear implant

External links

Cochlear Implants at Curlie
Cochlear Implants Information from the National Institutes of Health (NIH).
NASA Spinoff article on engineer Adam Kissiah's contribution to cochlear implants beginning in the 1970s.

[1] "NCD - Cochlear Implantation (50.3)". www.cms.gov. Retrieved 2021-11-22.

[:0-2] "Cochlear Implants". NIDCD. Retrieved 2021-11-22.

[3] Rayes H, Al-Malky G, Vickers D (May 2019). "Systematic Review of Auditory Training in Pediatric Cochlear Implant Recipients". Journal of Speech, Language, and Hearing Research. 62 (5): 1574–1593. doi:10.1044/2019_JSLHR-H-18-0252. PMID 31039327. S2CID 141503740.

[4] Henshaw H, Ferguson MA (2013-05-10). "Efficacy of individual computer-based auditory training for people with hearing loss: a systematic review of the evidence". PloS One. 8 (5): e62836. Bibcode:2013PLoSO...862836H. doi:10.1371/journal.pone.0062836. PMC 3651281. PMID 23675431.

[5] Sweetow R, Palmer CV (July 2005). "Efficacy of individual auditory training in adults: a systematic review of the evidence". Journal of the American Academy of Audiology. 16 (7): 494–504. doi:10.3766/jaaa.16.7.9. PMID 16295236.

[6] Naples JG, Ruckenstein MJ (February 2020). "Cochlear Implant". Otolaryngologic Clinics of North America. 53 (1): 87–102. doi:10.1016/j.otc.2019.09.004. PMID 31677740. S2CID 207890377.

[7] Clark GM (April 2015). "The multi-channel cochlear implant: multi-disciplinary development of electrical stimulation of the cochlea and the resulting clinical benefit". Hearing Research. 322: 4–13. doi:10.1016/j.heares.2014.08.002. PMID 25159273.

[8] Shannon RV (February 2012). "Advances in auditory prostheses". Current Opinion in Neurology. 25 (1): 61–66. doi:10.1097/WCO.0b013e32834ef878. PMC 4123811. PMID 22157109.

[9] Blamey P, Artieres F, Başkent D, Bergeron F, Beynon A, Burke E, et al. (2013). "Factors affecting auditory performance of postlinguistically deaf adults using cochlear implants: an update with 2251 patients". Audiology & Neuro-Otology. 18 (1): 36–47. doi:10.1159/000343189. PMID 23095305. S2CID 4668675.

[10] Başkent D, Gaudrain E, Tamati TN, Wagner A (2016). Cacace AT, de Kleine E, Holt AG, van Dijk P (eds.). Perception and psychoacoustics of speech in cochlear implant users, in Scientific Foundations of Audiology: Perspectives from Physics, Biology, Modeling, and Medicine,. San Diego, CA, USA: Plural Publishing, Inc. pp. 285–319.

[11] Pisoni DB, Kronenberger WG, Harris MS, Moberly AC (December 2017). "Three challenges for future research on cochlear implants". World Journal of Otorhinolaryngology - Head and Neck Surgery. 3 (4): 240–254. doi:10.1016/j.wjorl.2017.12.010. PMC 5956139. PMID 29780970.

[CBS_News-12] "The Cochlear Implant Controversy, Issues And Debates". CBS News. NEW YORK. September 4, 2001. Retrieved 2021-05-08.

[Svirsky2017-13] Svirsky M (2017). "Cochlear implants and electronic hearing". Physics Today. 70 (8): 52–58. Bibcode:2017PhT....70h..52S. doi:10.1063/PT.3.3661. ISSN 0031-9228.

[nytimes-14] Martin D (December 15, 2012). "Dr. William F. House, Inventor of Pioneering Ear-Implant Device, Dies at 89". The New York Times. Retrieved 2012-12-16.

[MudryHist-15] Mudry A, Mills M (May 2013). "The early history of the cochlear implant: a retrospective". JAMA Otolaryngology-- Head & Neck Surgery. 139 (5): 446–453. doi:10.1001/jamaoto.2013.293. PMID 23681026.

[16] Clark G (2009). "The multi-channel cochlear implant: past, present and future perspectives". Cochlear Implants International. 10 (Suppl 1): 2–13. doi:10.1179/cim.2009.10.Supplement-1.2. PMID 19127562. S2CID 30532987.

[Spinoff2003-17] NASA (2003). NASA space station. Washington, DC: U.S. Government Printing. Archived from the original on 2003-10-18.

[18] "2013 Lasker~DeBakey Clinical Medical Research Award: Modern cochlear implant". The Lasker Foundation. Retrieved 14 July 2017.

[2016Horizon-19] Roche JP, Hansen MR (December 2015). "On the Horizon: Cochlear Implant Technology". Otolaryngologic Clinics of North America. 48 (6): 1097–1116. doi:10.1016/j.otc.2015.07.009. PMC 4641792. PMID 26443490.

[NIDCD2016-20] NIH Publication No. 11-4798 (2013-11-01). "Cochlear Implants". National Institute on Deafness and Other Communication Disorders. Retrieved February 18, 2016.{{cite web}}: CS1 maint: numeric names: authors list (link)

[2015f1000-21] Yawn R, Hunter JB, Sweeney AD, Bennett ML (2015). "Cochlear implantation: a biomechanical prosthesis for hearing loss". F1000Prime Reports. 7: 45. doi:10.12703/P7-45. PMC 4447036. PMID 26097718.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[22] Cohen N (April 2007). "The totally implantable cochlear implant". Ear and Hearing. 28 (2 Suppl): 100S–101S. doi:10.1097/AUD.0b013e31803150f4. PMID 17496658. S2CID 38696317.

[23] "Induction Neckloops - Bluetooth Neckloop". ADCO Hearing Products. Retrieved 2021-12-09.

[24] "Phonak Roger Pen". www.ihear.co.uk. Retrieved 2021-12-09.

[25] "AudioStream - Connect Your MED-EL Cochlear Implant". www.medel.com. Retrieved 2021-12-09.

[26] "Using the telephone". cochlear implant HELP. 2012-03-29. Retrieved 2021-12-09.

[27] Hoff S, Ryan M, Thomas D, Tournis E, Kenny H, Hajduk J, Young NM (April 2019). "Safety and Effectiveness of Cochlear Implantation of Young Children, Including Those With Complicating Conditions". Otology & Neurotology. 40 (4): 454–463. doi:10.1097/MAO.0000000000002156. PMID 30870355.

[28] "Hearing aids vs cohclear implants: What's the difference?". www.medicalnewstoday.com. 2021-05-28. Retrieved 2021-12-01.

[2016procRev-29] Bruijnzeel H, Draaisma K, van Grootel R, Stegeman I, Topsakal V, Grolman W (April 2016). "Systematic Review on Surgical Outcomes and Hearing Preservation for Cochlear Implantation in Children and Adults". Otolaryngology--Head and Neck Surgery. 154 (4): 586–596. doi:10.1177/0194599815627146. PMID 26884363. S2CID 25594951.

[30] Tokita J, Dunn C, Hansen MR (October 2014). "Cochlear implantation and single-sided deafness". Current Opinion in Otolaryngology & Head and Neck Surgery. 22 (5): 353–358. doi:10.1097/moo.0000000000000080. PMC 4185341. PMID 25050566.

[31] Rajan P, Teh HM, Prepageran N, Kamalden TI, Tang P (2017-12-01). "Endoscopic Cochlear Implant: Literature Review and Current Status". Current Otorhinolaryngology Reports. 5 (4): 268–274. doi:10.1007/s40136-017-0164-2. ISSN 2167-583X. S2CID 80330932.

[32] Tarabichi M, Nazhat O, Kassouma J, Najmi M (March 2016). "Endoscopic cochlear implantation: Call for caution". The Laryngoscope. 126 (3): 689–692. doi:10.1002/lary.25462. PMID 26154143. S2CID 24799811.

[:1-33] Dornhoffer JR, Reddy P, Meyer TA, Schvartz-Leyzac KC, Dubno JR, McRackan TR (March 2021). "Individual Differences in Speech Recognition Changes After Cochlear Implantation". JAMA Otolaryngology-- Head & Neck Surgery. 147 (3): 280–286. doi:10.1001/jamaoto.2020.5094. PMID 33410869.

[:2-34] McRackan TR, Velozo CA, Holcomb MA, Camposeo EL, Hatch JL, Meyer TA, et al. (October 2017). "Use of Adult Patient Focus Groups to Develop the Initial Item Bank for a Cochlear Implant Quality-of-Life Instrument". JAMA Otolaryngology-- Head & Neck Surgery. 143 (10): 975–982. doi:10.1001/jamaoto.2017.1182. PMC 5710256. PMID 28772297.

[35] McRackan TR, Bauschard M, Hatch JL, Franko-Tobin E, Droghini HR, Nguyen SA, Dubno JR (April 2018). "Meta-analysis of quality-of-life improvement after cochlear implantation and associations with speech recognition abilities". The Laryngoscope. 128 (4): 982–990. doi:10.1002/lary.26738. PMID 28731538.

[36] McRackan TR, Bauschard M, Hatch JL, Franko-Tobin E, Droghini HR, Velozo CA, et al. (January 2018). "Meta-analysis of Cochlear Implantation Outcomes Evaluated With General Health-related Patient-reported Outcome Measures". Otology & Neurotology. 39 (1): 29–36. doi:10.1097/mao.0000000000001620. PMID 29227446.

[37] Hughes SE, Hutchings HA, Rapport FL, McMahon CM, Boisvert I (September 2018). "Social Connectedness and Perceived Listening Effort in Adult Cochlear Implant Users: A Grounded Theory to Establish Content Validity for a New Patient-Reported Outcome Measure". Ear and Hearing. 39 (5): 922–934. doi:10.1097/AUD.0000000000000553. PMID 29424766.

[38] McRackan TR, Hand BN, Velozo CA, Dubno JR (September 2019). "Cochlear Implant Quality of Life (CIQOL): Development of a Profile Instrument (CIQOL-35 Profile) and a Global Measure (CIQOL-10 Global)". Journal of Speech, Language, and Hearing Research. 62 (9): 3554–3563. doi:10.1044/2019_JSLHR-H-19-0142. PMC 6808347. PMID 31479616.

[:3-39] Leigh, I. W.; Maxwell-McCaw, D.; Bat-Chava, Y.; Christiansen, J. B. (2008-07-16). "Correlates of Psychosocial Adjustment in Deaf Adolescents With and Without Cochlear Implants: A Preliminary Investigation". Journal of Deaf Studies and Deaf Education. 14 (2): 244–259. doi:10.1093/deafed/enn038. ISSN 1081-4159.

[:4-40] Most, Tova; Wiesel, Amatzia; Blitzer, Tamar (June 2007). "Identity and Attitudes towards Cochlear Implant Among Deaf and Hard of Hearing Adolescents". Deafness & Education International. 9 (2): 68–82. doi:10.1179/146431507790560002. ISSN 1464-3154.

[41] Dammeyer, Jesper; Chapman, Madeleine; Marschark, Marc (2018). "Experience of Hearing Loss, Communication, Social Participation, and Psychological Well-Being Among Adolescents With Cochlear Implants". American Annals of the Deaf. 163 (4): 424–439. ISSN 0002-726X.

[42] Rak, Kristen; Völker, Johannes; Schendzielorz, Philipp; Shehata-Dieler, Wafaa; Radeloff, Andreas; Hagen, Rudolf (2019-03). "Bilateral cochlear implantation is regarded as very beneficial: results from a worldwide survey by online questionnaire". European archives of oto-rhino-laryngology: official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS): affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 276 (3): 679–683. doi:10.1007/s00405-018-05271-x. ISSN 1434-4726. PMID 30617425. {{cite journal}}: Check date values in: |date= (help)

[43] Kral A, O'Donoghue GM (October 2010). "Profound deafness in childhood". The New England Journal of Medicine. 363 (15): 1438–1450. doi:10.1056/NEJMra0911225. PMID 20925546. S2CID 13639137.

[44] Niparko JK, Tobey EA, Thal DJ, Eisenberg LS, Wang NY, Quittner AL, Fink NE (April 2010). "Spoken language development in children following cochlear implantation". Jama. 303 (15): 1498–1506. doi:10.1001/jama.2010.451. PMC 3073449. PMID 20407059.

[45] Ganek H, McConkey Robbins A, Niparko JK (February 2012). "Language outcomes after cochlear implantation". Otolaryngologic Clinics of North America. 45 (1): 173–185. doi:10.1016/j.otc.2011.08.024. PMID 22115689.

[46] Cheng, Li-Jen; Soon, Swee Sung; Wu, David Bin-Chia; Ju, Hong; Ng, Kwong (2019-08-15). "Cost-effectiveness analysis of bilateral cochlear implants for children with severe-to-profound sensorineural hearing loss in both ears in Singapore". PLOS ONE. 14 (8): e0220439. doi:10.1371/journal.pone.0220439. ISSN 1932-6203. PMC 6695111. PMID 31415595.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)

[47] Ramsden, James D.; Gordon, Karen; Aschendorff, Antje; Borucki, Lukasz; Bunne, Marie; Burdo, Sandro; Garabedian, Noel; Grolman, Wilko; Irving, Richard; Lesinski-Schiedat, Anke; Loundon, Natalie (2012-06). "European Bilateral Pediatric Cochlear Implant Forum Consensus Statement". Otology & Neurotology. 33 (4): 561–565. doi:10.1097/MAO.0b013e3182536ae2. ISSN 1531-7129. {{cite journal}}: Check date values in: |date= (help)

[48] Sivonen, Ville; Sinkkonen, Saku T.; Willberg, Tytti; Lamminmäki, Satu; Jääskelä-Saari, Hilkka; Aarnisalo, Antti A.; Dietz, Aarno (2021-01). "Improvements in Hearing and in Quality of Life after Sequential Bilateral Cochlear Implantation in a Consecutive Sample of Adult Patients with Severe-to-Profound Hearing Loss". Journal of Clinical Medicine. 10 (11): 2394. doi:10.3390/jcm10112394. {{cite journal}}: Check date values in: |date= (help)CS1 maint: unflagged free DOI (link)

[:5-49] Ramakers GG, van Zon A, Stegeman I, Grolman W (November 2015). "The effect of cochlear implantation on tinnitus in patients with bilateral hearing loss: A systematic review". The Laryngoscope. 125 (11): 2584–2592. doi:10.1002/lary.25370. PMID 26153087. S2CID 19088970.

[50] Mallen, Jonathan R.; Chiu, Jerlon; Marquis, Hillary; Ottochian, Amanda; Perez, Erin; Kuo, Chia-Ling; Otto, Steve; Ryan, Tessa; Roberts, Daniel S. (2020). "Quantifying tinnitus suppression in cochlear implantation using tinnitus interval-limited tracking". The Laryngoscope. 130 (8): 2047–2052. doi:10.1002/lary.28414. ISSN 1531-4995.

[51] Harrison RV, Gordon KA, Papsin BC, Negandhi J, James AL (December 2015). "Auditory neuropathy spectrum disorder (ANSD) and cochlear implantation". International Journal of Pediatric Otorhinolaryngology. 79 (12): 1980–1987. doi:10.1016/j.ijporl.2015.10.006. PMID 26545793.

[:6-52] Beyea JA, McMullen KP, Harris MS, Houston DM, Martin JM, Bolster VA, et al. (October 2016). "Cochlear Implants in Adults: Effects of Age and Duration of Deafness on Speech Recognition". Otology & Neurotology. 37 (9): 1238–1245. doi:10.1097/MAO.0000000000001162. PMID 27466894. S2CID 10143665.

[53] Schafer, Erin C.; Miller, Sharon; Manning, Jacy; Zhang, Qi; Lavi, Alexandra; Bodish, Emily; Fuentes, Andrea; De, Blaey Eric (2021-09-10). "Meta-Analysis of Speech Recognition Outcomes in Younger and Older Adults With Cochlear Implants". American Journal of Audiology. 30 (3): 481–496. doi:10.1044/2021_AJA-20-00141.

[54] Livingston, Gill; Huntley, Jonathan; Sommerlad, Andrew; Ames, David; Ballard, Clive; Banerjee, Sube; Brayne, Carol; Burns, Alistair; Cohen-Mansfield, Jiska; Cooper, Claudia; Costafreda, Sergi G. (2020-08-08). "Dementia prevention, intervention, and care: 2020 report of the Lancet Commission". The Lancet. 396 (10248): 413–446. doi:10.1016/S0140-6736(20)30367-6. ISSN 0140-6736. PMID 32738937.

[55] Speers, Amanda; George, Asha; Toner, Joseph (2015-01-01). "An aging concern: A retrospective study comparing the audiological and speech outcome measures along with the surgical and quality-of-life outcomes in a group of geriatric patients with those of an adult control group". Cochlear Implants International. 16 (sup1): S3–S5. doi:10.1179/1467010014Z.000000000222. ISSN 1467-0100. PMID 25614263.

[2016cabral-56] Cabral Junior F, Pinna MH, Alves RD, Malerbi AF, Bento RF (January 2016). "Cochlear Implantation and Single-sided Deafness: A Systematic Review of the Literature". International Archives of Otorhinolaryngology. 20 (1): 69–75. doi:10.1055/s-0035-1559586. PMC 4687988. PMID 26722349.

[57] Crowson, Matthew G.; Semenov, Yevgeniy R.; Tucci, Debara L.; Niparko, John K. (2017). "Quality of Life and Cost-Effectiveness of Cochlear Implants: A Narrative Review". Audiology and Neurotology. 22 (4–5): 236–258. doi:10.1159/000481767. ISSN 1420-3030. PMID 29262414.

[58] "NIH Fact Sheets - Cochlear Implants". report.nih.gov. Archived from the original on 2011-10-22. Retrieved 2018-09-14.

[59] "Cochlear Implant Information Sheet". The Ear Foundation. Archived from the original on 2017-07-11. Retrieved 2018-09-14.

[60] "Cochlear Implants". American Academy of Otolaryngology–Head and Neck Surgery. 21 April 2014. Archived from the original on 24 August 2017. Retrieved 12 May 2017.

[61] "Beaumont Hospital - Cochlear Implant - How to Refer".

[62] "Coût de l'implant cochléaire". CISIC.fr (in French). Centre d'Information sur la Surdité et l'Implant Cochléaire.

[63] Williams JM (2000-05-05). "Do Health-Care Providers Have to Pay for Assistive Tech?". Business Week. Retrieved 2009-10-25.

[64] D'Haese, Patrick S. C.; Van Rompaey, Vincent; De Bodt, Marc; Van de Heyning, Paul (2019). "Severe Hearing Loss in the Aging Population Poses a Global Public Health Challenge. How Can We Better Realize the Benefits of Cochlear Implantation to Mitigate This Crisis?". Frontiers in Public Health. 7: 227. doi:10.3389/fpubh.2019.00227. ISSN 2296-2565.{{cite journal}}: CS1 maint: unflagged free DOI (link)

[:7-65] "World report on hearing". www.who.int. Retrieved 2021-12-09.

[66] Lock, M. and Nguyen, V-K., An Anthropology of Biomedicine, Oxford, Wiley-Blackwell, 2010.^{[page needed]}

[Power,_D._2005,_pp._451-459-67] Power D (2005). "Models of deafness: cochlear implants in the Australian daily press". Journal of Deaf Studies and Deaf Education. 10 (4): 451–459. doi:10.1093/deafed/eni042. PMID 16000690.

[UCIResearch-68] Oginni P (2009-11-16). "UCI Research with Cochlear Implants No Longer Falling on Deaf Ears". New University. Retrieved 2009-11-18.

[Hall2019-69] Hall ML, Hall WC, Caselli NK (2019). "Deaf children need language, not (Just) speech". First Language. 39 (4): 367–395. doi:10.1177/0142723719834102. S2CID 140083091.

[70] NAD Cochlear Implant Committee. "Cochlear Implants". Archived from the original on 2007-02-20.

[71] Hicks K (2016-08-05). "We Are Not Language Deprived".

[Atlantic-72] Ringo A (August 9, 2013). "Understanding Deafness: Not Everyone Wants to Be 'Fixed'". The Atlantic.

[73] Johnston T (2004). "W(h)ither the deaf community? Population, genetics, and the future of Australian sign language". American Annals of the Deaf. 148 (5): 358–375. doi:10.1353/aad.2004.0004. PMID 15132016. S2CID 21638387.

[74] Christiansen JB, Leigh IW, Spencer PE, Lucker JR (2001). Cochlear implants in children : ethics and choices ([Online-Ausg.] ed.). Washington, D.C.: Gallaudet University Press. pp. 304–305. ISBN 9781563681165.

[75] De Vera N, Dharer Y. "Bilingual-Bicultural Education of Deaf/Hard-of- Hearing Children". deafed. Retrieved 9 February 2020.

[76] Denworth L (April 25, 2014). "Science Gave My Son the Gift of Sound". Time.

[77] Geers A (2017-07-01). "Early Sign Language Exposure and Cochlear Implantation Benefits".

[78] 3D microscaffold cochlear implant

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

[17]

[18]

[19]

[20]

[21]

[22]

[23]

[24]

[25]

[26]

[27]

[28]

[29]

[30]

[31]

[32]

[33]

[34]

[35]

[36]

[37]

[38]

[39]

[40]

[41]

[42]

[43]

[44]

[45]

[46]

[47]

[48]

[49]

[50]

[51]

[52]

[53]

[54]

[55]

[56]

[57]

[58]

[59]

[60]

[61]

[62]

[63]

[64]

[65]

[66]

[67]

[68]

[69]

[70]

[71]

[72]

[73]

[74]

[75]

[76]

[77]

[78]

@@ Line 1: / Line 1: @@
-{{Short description|Prosthesis providing a sense of sound}}
 {{Infobox medical intervention
 | Name         = Cochlear implant
@@ Line 50: / Line 49: @@
 * an electrode array embedded in the cochlea
 A [[totally implantable cochlear implant (TICI)]] is currently in development. This new type of cochlear implant incorporates all the current external components of an audio processor into the internal implant. The lack of external components makes the implant invisible from the outside and also means it is less likely to suffer damage and breakages.<ref>{{cite journal | vauthors = Cohen N | title = The totally implantable cochlear implant | language = en-US | journal = Ear and Hearing | volume = 28 | issue = 2 Suppl | pages = 100S-101S | date = April 2007 | pmid = 17496658 | doi = 10.1097/AUD.0b013e31803150f4 | s2cid = 38696317 }}</ref>
+=== Assistive listening devices ===
+Most modern cochlear implants can be used with a range of assistive listening devices (ALDs), which help people to hear better in challenging listening situations. These situations could include talking on the phone, watching TV or listening to a speaker or teacher. With an ALD, the sound from devices including mobile phones or from an external microphone is sent to the audio processor directly, rather than being picked up by the audio processor’s microphone. This direct transmission improves the sound quality for the user, making it easier to talk on the phone or stream music.
+ALDs come in many forms, such as neckloops,<ref>{{Cite web|title=Induction Neckloops - Bluetooth Neckloop|url=https://adcohearing.com/collections/induction-loops-neckloops|access-date=2021-12-09|website=ADCO Hearing Products|language=en}}</ref> pens,<ref>{{Cite web|title=Phonak Roger Pen|url=https://www.ihear.co.uk/products/phonak-roger-pen|access-date=2021-12-09|website=www.ihear.co.uk|language=en}}</ref> and specialist battery pack covers.<ref>{{Cite web|title=AudioStream - Connect Your MED-EL Cochlear Implant|url=https://www.medel.com/hearing-solutions/accessories/connectivity/audiostream|access-date=2021-12-09|website=www.medel.com|language=en}}</ref> Modern ALDs are usually able to receive sound from any Bluetooth device, including phones and computers, before transmitting it wirelessly to the audio processor. Most cochlear implants are also compatible with older ALD technology, such as a telecoil.<ref>{{Cite web|date=2012-03-29|title=Using the telephone|url=https://cochlearimplanthelp.com/journey/getting-connected/using-the-telephone/|access-date=2021-12-09|website=cochlear implant HELP|language=en}}</ref>
 ==Surgical procedure==
@@ Line 76: / Line 80: @@
 ==Efficacy==
+A 2019 study found that bilateral cochlear implantation was widely regarded as the most beneficial hearing intervention for acceptable candidates, although it is more likely to be performed and reimbursed in children than adults. The study also found that the efficacy of bilateral implantation could be improved by enhancing communication between the two implants and by developing sound coding strategies specifically for bilateral users.<ref>{{Cite journal|last=Rak|first=Kristen|last2=Völker|first2=Johannes|last3=Schendzielorz|first3=Philipp|last4=Shehata-Dieler|first4=Wafaa|last5=Radeloff|first5=Andreas|last6=Hagen|first6=Rudolf|date=2019-03|title=Bilateral cochlear implantation is regarded as very beneficial: results from a worldwide survey by online questionnaire|url=https://pubmed.ncbi.nlm.nih.gov/30617425/|journal=European archives of oto-rhino-laryngology: official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS): affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery|volume=276|issue=3|pages=679–683|doi=10.1007/s00405-018-05271-x|issn=1434-4726|pmid=30617425}}</ref>
-A 2011 AHRQ review of the evidence of the effectiveness of CI in people with bilateral hearing loss — the device's primary use — found low to moderate quality data{{According to whom|date=October 2021}} that showed [[speech perception]] in noisy conditions was much better for people who had implants in both ears done at the same time compared to people who had only one. The data also showed that no conclusions could be drawn about changes in speech perception in quiet conditions and health-related quality of life. There was only one good study{{According to whom|date=October 2021}} comparing implanting implants in both ears at the same time to implanting them sequentially; this study found that in the sequential approach, the second implantation made no change, or made things worse.<ref name="AHRQ2011">{{cite book |pmid=25927131 | vauthors = Raman G, Lee J, Chung M, Gaylor JM, Sen S, Rao M, Lau J, Poe DS, Neault MW | display-authors = 6 |title=Effectiveness of Cochlear Implants in Adults With Sensorineural Hearing Loss [Internet]  |url=https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0073442/pdf/PubMedHealth_PMH0073442.pdf|location=Rockville (MD) |publisher=Agency for Healthcare Research and Quality |date=17 June 2011 }}</ref>
-Several 2010 and 2012 reviews found that the ability to communicate in spoken language was better the earlier the implantation was performed. The reviews also found that, overall, while cochlear implants provide open set speech understanding for the majority of implanted profoundly hearing-impaired children, the efficacy of cochlear implants is highly variable, and depends on factors such as parental involvement, parental education level, and amount of spoken language exposure.<ref>{{cite journal | vauthors = Kral A, O'Donoghue GM | title = Profound deafness in childhood | journal = The New England Journal of Medicine | volume = 363 | issue = 15 | pages = 1438–1450 | date = October 2010 | pmid = 20925546 | doi = 10.1056/NEJMra0911225 | s2cid = 13639137 }}</ref><ref>{{cite journal | vauthors = Niparko JK, Tobey EA, Thal DJ, Eisenberg LS, Wang NY, Quittner AL, Fink NE | title = Spoken language development in children following cochlear implantation | journal = Jama | volume = 303 | issue = 15 | pages = 1498–1506 | date = April 2010 | pmid = 20407059 | pmc = 3073449 | doi = 10.1001/jama.2010.451 }}</ref><ref>{{cite journal | vauthors = Ganek H, McConkey Robbins A, Niparko JK | title = Language outcomes after cochlear implantation | journal = Otolaryngologic Clinics of North America | volume = 45 | issue = 1 | pages = 173–185 | date = February 2012 | pmid = 22115689 | doi = 10.1016/j.otc.2011.08.024 | author3-link = John Niparko }}</ref>
+Early research reviews found that the ability to communicate in spoken language was better the earlier the implantation was performed. The reviews also found that, overall, while cochlear implants provide open set speech understanding for the majority of implanted profoundly hearing-impaired children, and that it was not possible to accurately predict the specific outcome of the given implanted child.<ref>{{cite journal | vauthors = Kral A, O'Donoghue GM | title = Profound deafness in childhood | journal = The New England Journal of Medicine | volume = 363 | issue = 15 | pages = 1438–1450 | date = October 2010 | pmid = 20925546 | doi = 10.1056/NEJMra0911225 | s2cid = 13639137 }}</ref><ref>{{cite journal | vauthors = Niparko JK, Tobey EA, Thal DJ, Eisenberg LS, Wang NY, Quittner AL, Fink NE | title = Spoken language development in children following cochlear implantation | journal = Jama | volume = 303 | issue = 15 | pages = 1498–1506 | date = April 2010 | pmid = 20407059 | pmc = 3073449 | doi = 10.1001/jama.2010.451 }}</ref><ref>{{cite journal | vauthors = Ganek H, McConkey Robbins A, Niparko JK | title = Language outcomes after cochlear implantation | journal = Otolaryngologic Clinics of North America | volume = 45 | issue = 1 | pages = 173–185 | date = February 2012 | pmid = 22115689 | doi = 10.1016/j.otc.2011.08.024 | author3-link = John Niparko }}</ref> Research since then has reported long-term socio-economic benefits for children as well as audiological outcomes including improved sound localization and speech perception.<ref>{{Cite journal|last=Cheng|first=Li-Jen|last2=Soon|first2=Swee Sung|last3=Wu|first3=David Bin-Chia|last4=Ju|first4=Hong|last5=Ng|first5=Kwong|date=2019-08-15|title=Cost-effectiveness analysis of bilateral cochlear implants for children with severe-to-profound sensorineural hearing loss in both ears in Singapore|url=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220439|journal=PLOS ONE|language=en|volume=14|issue=8|pages=e0220439|doi=10.1371/journal.pone.0220439|issn=1932-6203|pmc=PMC6695111|pmid=31415595}}</ref>  A consensus statement from the European Bilateral Pediatric Cochlear Implant Forum also confirmed the importance of bilateral cochlear implantation in children.<ref>{{Cite journal|last=Ramsden|first=James D.|last2=Gordon|first2=Karen|last3=Aschendorff|first3=Antje|last4=Borucki|first4=Lukasz|last5=Bunne|first5=Marie|last6=Burdo|first6=Sandro|last7=Garabedian|first7=Noel|last8=Grolman|first8=Wilko|last9=Irving|first9=Richard|last10=Lesinski-Schiedat|first10=Anke|last11=Loundon|first11=Natalie|date=2012-06|title=European Bilateral Pediatric Cochlear Implant Forum Consensus Statement|url=https://journals.lww.com/otology-neurotology/Abstract/2012/06000/European_Bilateral_Pediatric_Cochlear_Implant.12.aspx|journal=Otology & Neurotology|language=en-US|volume=33|issue=4|pages=561–565|doi=10.1097/MAO.0b013e3182536ae2|issn=1531-7129}}</ref> In adults, new research shows that bilateral implantation can improve quality of life and speech intelligibility in quiet and noise.<ref>{{Cite journal|last=Sivonen|first=Ville|last2=Sinkkonen|first2=Saku T.|last3=Willberg|first3=Tytti|last4=Lamminmäki|first4=Satu|last5=Jääskelä-Saari|first5=Hilkka|last6=Aarnisalo|first6=Antti A.|last7=Dietz|first7=Aarno|date=2021-01|title=Improvements in Hearing and in Quality of Life after Sequential Bilateral Cochlear Implantation in a Consecutive Sample of Adult Patients with Severe-to-Profound Hearing Loss|url=https://www.mdpi.com/2077-0383/10/11/2394|journal=Journal of Clinical Medicine|language=en|volume=10|issue=11|pages=2394|doi=10.3390/jcm10112394}}</ref>
-A 2012 review concluded that, in most of the cases, cochlear implantation in single-sided deafness suppressed tinnitus, and no tinnitus worsening was reported.<ref>{{Cite journal|last=Arts|first=Remo A. G. J.|last2=George|first2=Erwin L. J.|last3=Stokroos|first3=Robert J.|last4=Vermeire|first4=Katrien|date=October 2012|title=Review:  cochlear implants as a treatment of tinnitus in single-sided deafness|url=https://pubmed.ncbi.nlm.nih.gov/22931903/|journal=Current Opinion in Otolaryngology & Head and Neck Surgery|volume=20|issue=5|pages=398–403|doi=10.1097/MOO.0b013e3283577b66|issn=1531-6998|pmid=22931903}}</ref> A 2015 review examined whether CI implantation to treat people with bilateral hearing loss had any effect on [[tinnitus]]. Overall, the review found that unilateral cochlear implantation decreased the mean tinnitus questionnaire score.<ref name=":5" /> This review found the quality of evidence to be poor and the results variable: overall total tinnitus suppression rates for patients who had tinnitus prior to surgery varied from 8% to 45% of people who received CI; decrease of tinnitus was seen in 25% to 72%, of people; for 0% to 36% of the people there was no change; increase of tinnitus occurred in between 0% to 25% of patients; and, in between 0 and 10% of cases, people who did not have tinnitus before the procedure, got it.<ref name=":5">{{cite journal | vauthors = Ramakers GG, van Zon A, Stegeman I, Grolman W | title = The effect of cochlear implantation on tinnitus in patients with bilateral hearing loss: A systematic review | journal = The Laryngoscope | volume = 125 | issue = 11 | pages = 2584–2592 | date = November 2015 | pmid = 26153087 | doi = 10.1002/lary.25370 | s2cid = 19088970 }}</ref>
+A 2015 review examined whether CI implantation to treat people with bilateral hearing loss had any effect on [[tinnitus]]. This review found the quality of evidence to be poor and the results variable: overall total tinnitus suppression rates for patients who had tinnitus prior to surgery varied from 8% to 45% of people who received CI; decrease of tinnitus was seen in 25% to 72%, of people; for 0% to 36% of the people there was no change; increase of tinnitus occurred in between 0% to 25% of patients; and, in between 0 and 10% of cases, people who did not have tinnitus before the procedure, got it.<ref name=":5">{{cite journal | vauthors = Ramakers GG, van Zon A, Stegeman I, Grolman W | title = The effect of cochlear implantation on tinnitus in patients with bilateral hearing loss: A systematic review | journal = The Laryngoscope | volume = 125 | issue = 11 | pages = 2584–2592 | date = November 2015 | pmid = 26153087 | doi = 10.1002/lary.25370 | s2cid = 19088970 }}</ref> Further research found that the electrical stimulation of the CI is at least partly responsible for the general reduction in symptoms. A 2019 study found that although tinnitus suppression in patients with CIs is multifactorial, simply having the CI switched on without any audiological input (while standing alone in a soundproof booth) reduced the symptoms of tinnitus. This would suggest that it is the electrical stimulation that explains the decrease in tinnitus symptoms for many patients, and not only the increased access to sound.<ref>{{Cite journal|last=Mallen|first=Jonathan R.|last2=Chiu|first2=Jerlon|last3=Marquis|first3=Hillary|last4=Ottochian|first4=Amanda|last5=Perez|first5=Erin|last6=Kuo|first6=Chia-Ling|last7=Otto|first7=Steve|last8=Ryan|first8=Tessa|last9=Roberts|first9=Daniel S.|date=2020|title=Quantifying tinnitus suppression in cochlear implantation using tinnitus interval-limited tracking|url=https://onlinelibrary.wiley.com/doi/abs/10.1002/lary.28414|journal=The Laryngoscope|language=en|volume=130|issue=8|pages=2047–2052|doi=10.1002/lary.28414|issn=1531-4995}}</ref>
 A 2015 literature review on the use of CI for people with [[auditory neuropathy spectrum disorder]] found that, as of that date, description and diagnosis of the condition was too heterogeneous to make clear claims about whether CI is a safe and effective way to manage it.<ref>{{cite journal | vauthors = Harrison RV, Gordon KA, Papsin BC, Negandhi J, James AL | title = Auditory neuropathy spectrum disorder (ANSD) and cochlear implantation | journal = International Journal of Pediatric Otorhinolaryngology | volume = 79 | issue = 12 | pages = 1980–1987 | date = December 2015 | pmid = 26545793 | doi = 10.1016/j.ijporl.2015.10.006 }}</ref>
-A 2016 research study found that age at implantation was highly correlated with post-operative speech understanding performance for various test measures. In this study, people who were implanted at age 65 or older performed significantly worse on speech perception testing in quiet and in noisy conditions compared to younger CI users. The deleterious effects of aging on central auditory processing abilities are thought to play an important role in impacting an individual's speech perception abilities with CI. Prolonged duration of deafness is another factor that is thought to have a negative impact on overall speech understanding outcomes for CI users. However, this particular study found no statistical difference in the speech understanding abilities of CI patients over 65 who had been hearing impaired for 30 years or more prior to implantation.<ref>{{cite journal | vauthors = Beyea JA, McMullen KP, Harris MS, Houston DM, Martin JM, Bolster VA, Adunka OF, Moberly AC | display-authors = 6 | title = Cochlear Implants in Adults: Effects of Age and Duration of Deafness on Speech Recognition | journal = Otology & Neurotology | volume = 37 | issue = 9 | pages = 1238–1245 | date = October 2016 | pmid = 27466894 | doi = 10.1097/MAO.0000000000001162 | s2cid = 10143665 }}</ref> In general, outcomes for CI patients are dependent upon the individual's level of motivation, expectations, exposure to speech stimuli and consistent participation in aural rehabilitation programs.
+The data for cochlear implant outcomes in older adults differs. A 2016 research study found that age at implantation was highly correlated with post-operative speech understanding performance for various test measures. In this study, people who were implanted at age 65 or older performed significantly worse on speech perception testing in quiet and in noisy conditions compared to younger CI users.<ref name=":6">{{cite journal | vauthors = Beyea JA, McMullen KP, Harris MS, Houston DM, Martin JM, Bolster VA, Adunka OF, Moberly AC | display-authors = 6 | title = Cochlear Implants in Adults: Effects of Age and Duration of Deafness on Speech Recognition | journal = Otology & Neurotology | volume = 37 | issue = 9 | pages = 1238–1245 | date = October 2016 | pmid = 27466894 | doi = 10.1097/MAO.0000000000001162 | s2cid = 10143665 }}</ref> Other studies have shown different outcomes, with some reporting that adults implanted at the age of 65 and older showed audiological and speech discrimination outcomes similar to younger adults.<ref>{{Cite journal|last=Schafer|first=Erin C.|last2=Miller|first2=Sharon|last3=Manning|first3=Jacy|last4=Zhang|first4=Qi|last5=Lavi|first5=Alexandra|last6=Bodish|first6=Emily|last7=Fuentes|first7=Andrea|last8=De|first8=Blaey Eric|date=2021-09-10|title=Meta-Analysis of Speech Recognition Outcomes in Younger and Older Adults With Cochlear Implants|url=https://pubs.asha.org/doi/10.1044/2021_AJA-20-00141|journal=American Journal of Audiology|volume=30|issue=3|pages=481–496|doi=10.1044/2021_AJA-20-00141}}</ref>
+The effects of aging on central auditory processing abilities are thought to play an important role in impacting an individual's speech perception with a cochlear implant.  The Lancet reported that untreated hearing loss in adults is the number one modifiable risk factor for dementia.<ref>{{Cite journal|last=Livingston|first=Gill|last2=Huntley|first2=Jonathan|last3=Sommerlad|first3=Andrew|last4=Ames|first4=David|last5=Ballard|first5=Clive|last6=Banerjee|first6=Sube|last7=Brayne|first7=Carol|last8=Burns|first8=Alistair|last9=Cohen-Mansfield|first9=Jiska|last10=Cooper|first10=Claudia|last11=Costafreda|first11=Sergi G.|date=2020-08-08|title=Dementia prevention, intervention, and care: 2020 report of the Lancet Commission|url=https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30367-6/abstract|journal=The Lancet|language=English|volume=396|issue=10248|pages=413–446|doi=10.1016/S0140-6736(20)30367-6|issn=0140-6736|pmid=32738937}}</ref>  In 2017, a study also reported that adults using a cochlear implant had significantly improved cognitive outcomes including working memory, reaction time, and cognitive flexibility compared to people who were waiting to receive a cochlear implant.<ref>{{Cite journal|last=Speers|first=Amanda|last2=George|first2=Asha|last3=Toner|first3=Joseph|date=2015-01-01|title=An aging concern: A retrospective study comparing the audiological and speech outcome measures along with the surgical and quality-of-life outcomes in a group of geriatric patients with those of an adult control group|url=https://doi.org/10.1179/1467010014Z.000000000222|journal=Cochlear Implants International|volume=16|issue=sup1|pages=S3–S5|doi=10.1179/1467010014Z.000000000222|issn=1467-0100|pmid=25614263}}</ref>
-A 2016 systematic review of CI for people with [[unilateral hearing loss]] (UHL) found that of the studies conducted and published, none were randomized, only one evaluated a control group, and no study was blinded. After eliminating multiple uses of the same subjects, the authors found that 137 people with UHL had received a CI.<ref name=2016cabral>{{cite journal | vauthors = Cabral Junior F, Pinna MH, Alves RD, Malerbi AF, Bento RF | title = Cochlear Implantation and Single-sided Deafness: A Systematic Review of the Literature | journal = International Archives of Otorhinolaryngology | volume = 20 | issue = 1 | pages = 69–75 | date = January 2016 | pmid = 26722349 | pmc = 4687988 | doi = 10.1055/s-0035-1559586 }}</ref> While acknowledging the weakness of the data, the authors found that CI in people with UHL improves [[sound localization]] compared with other treatments in people who lost hearing after they learned to speak; in the one study that examined this, CI did improve sound localization in people with UHL who lost hearing before learning to speak.<ref name=2016cabral/> It appeared to improve [[speech perception]] and to reduce [[tinnitus]].<ref name=2016cabral/>
+Prolonged duration of deafness is another factor that is thought to have a negative impact on overall speech understanding outcomes for CI users. However, a study found no statistical difference in the speech understanding abilities of CI patients over 65 who had been hearing impaired for 30 years or more prior to implantation.<ref name=":6" /> In general, outcomes for CI patients are dependent upon the individual's level of motivation, expectations, exposure to speech stimuli and consistent participation in aural rehabilitation programs.
+A 2016 systematic review of CI for people with [[unilateral hearing loss]] (UHL) found that of the studies conducted and published, none were randomized, only one evaluated a control group, and no study was blinded. After eliminating multiple uses of the same subjects, the authors found that 137 people with UHL had received a CI.<ref name="2016cabral">{{cite journal | vauthors = Cabral Junior F, Pinna MH, Alves RD, Malerbi AF, Bento RF | title = Cochlear Implantation and Single-sided Deafness: A Systematic Review of the Literature | journal = International Archives of Otorhinolaryngology | volume = 20 | issue = 1 | pages = 69–75 | date = January 2016 | pmid = 26722349 | pmc = 4687988 | doi = 10.1055/s-0035-1559586 }}</ref> While acknowledging the weakness of the data, the authors found that CI in people with UHL improves [[sound localization]] compared with other treatments in people who lost hearing after they learned to speak; in the one study that examined this, CI did improve sound localization in people with UHL who lost hearing before learning to speak.<ref name="2016cabral" /> It appeared to improve [[speech perception]] and to reduce [[tinnitus]].<ref name="2016cabral" />
+In terms of quality of life, several studies have shown that cochlear implants are beneficial in many aspects of quality of life, including communication improvements and positive effects on social, emotional, psychological and physical well-being.  A 2017 narrative review also concluded that the quality of life scores of children using cochlear implants were comparable to those of children without hearing loss. Studies involving adults of all ages reported significant improvement in QoL after implantation when compared to adults with hearing aids.  This was often independent of audiological performance.<ref>{{Cite journal|last=Crowson|first=Matthew G.|last2=Semenov|first2=Yevgeniy R.|last3=Tucci|first3=Debara L.|last4=Niparko|first4=John K.|date=2017|title=Quality of Life and Cost-Effectiveness of Cochlear Implants: A Narrative Review|url=https://www.karger.com/Article/FullText/481767|journal=Audiology and Neurotology|language=english|volume=22|issue=4-5|pages=236–258|doi=10.1159/000481767|issn=1420-3030|pmid=29262414}}</ref>
 ==Society and culture==
@@ Line 97: / Line 107: @@
 A study by [[Johns Hopkins University]] determined that for a three-year-old child who receives them, cochlear implants can save $30,000 to $50,000 in special-education costs for elementary and secondary schools as the child is more likely to be mainstreamed in school and thus use fewer support services than similarly deaf children.<ref>{{cite web|url= http://www.businessweek.com/bwdaily/dnflash/may2000/nf00505c.htm|title= Do Health-Care Providers Have to Pay for Assistive Tech?|access-date= 2009-10-25| vauthors = Williams JM |date= 2000-05-05|publisher= [[Business Week]]}}</ref>
+=== Public Health ===
+.1% of the world population live with hearing loss, and it is predicted that by 2050, more than 900 million people around the globe will have a disabling hearing loss.<ref>{{Cite journal|last=D'Haese|first=Patrick S. C.|last2=Van Rompaey|first2=Vincent|last3=De Bodt|first3=Marc|last4=Van de Heyning|first4=Paul|date=2019|title=Severe Hearing Loss in the Aging Population Poses a Global Public Health Challenge. How Can We Better Realize the Benefits of Cochlear Implantation to Mitigate This Crisis?|url=https://www.frontiersin.org/article/10.3389/fpubh.2019.00227|journal=Frontiers in Public Health|volume=7|pages=227|doi=10.3389/fpubh.2019.00227|issn=2296-2565}}</ref> According to a WHO report, unaddressed hearing loss costs the world 980 billion dollars annually. Particularly hard hit are the healthcare and educational sectors, as well as societal costs. 53% of these costs are attributable to low- and middle-income countries.<ref name=":7">{{Cite web|title=World report on hearing|url=https://www.who.int/publications-detail-redirect/world-report-on-hearing|access-date=2021-12-09|website=www.who.int|language=en}}</ref>
+The WHO reports that cochlear implants have been shown to be a cost-effective way to mitigate the challenges of hearing loss. In a low-to-middle-income setting, every dollar invested in unilateral cochlear implants has a return on investment of 1.46 dollars. This rises to a return on investment of 4.09 dollars in an upper-middle-income setting. A study in Colombia assessed the lifetime investments made in 68 children who received cochlear implants at an early age. Taking into account the cost of the device and any other medical costs, follow-up, speech therapy, batteries and travel, each child required an average investment of US$ 99 000 over the course of their life (assuming a life span of 78 years for women and 72 years for men). The study concluded that for every dollar invested in rehabilitation of a child with a cochlear implant, there was a return on investment of US$ 2.07.<ref name=":7" />
 ===Manufacturers===