Jump to content

Friedhelm Hummel: Difference between revisions

Add links
From Wikipedia, the free encyclopedia
Browse history interactively
← Previous editNext edit →
Content deleted Content added
VisualWikitext
m spelling mistake
Further improvements, research section rewritten
Line 63: Line 63:
Hummel studied medicine at [[University of Tübingen]] and at [[Bordeaux Segalen University]] and graduated in 1998. He then joined the Department of Neurology at University of Tübingen as a medical resident and researcher.<ref>{{Cite journal|date=2003-10-01|title=Event-related desynchronization and excitability of the ipsilateral motor cortex during simple self-paced finger movements|url=https://www.sciencedirect.com/science/article/abs/pii/S1388245703001743|journal=Clinical Neurophysiology|language=en|volume=114|issue=10|pages=1819–1826|doi=10.1016/S1388-2457(03)00174-3|issn=1388-2457|last1=Rau|first1=Cornelia|last2=Plewnia|first2=Christian|last3=Hummel|first3=Friedhelm|last4=Gerloff|first4=Christian|pmid=14499743|s2cid=39272563}}</ref> He earned his medical doctor in 2000 for his work on ''Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate: eine Studie langsamer Potentiale'' (Plastic changes through semantic classical conditioning and their electrocortical correlates: a study of slow potentials).<ref>{{Cite book|last=Hummel|first=Friedhelm C.|url=https://rds-tue.ibs-bw.de/link?kid=1158454910|title=Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate eine Studie langsamer Potentiale|date=2000|location=Tübingen}}</ref>
Hummel studied medicine at [[University of Tübingen]] and at [[Bordeaux Segalen University]] and graduated in 1998. He then joined the Department of Neurology at University of Tübingen as a medical resident and researcher.<ref>{{Cite journal|date=2003-10-01|title=Event-related desynchronization and excitability of the ipsilateral motor cortex during simple self-paced finger movements|url=https://www.sciencedirect.com/science/article/abs/pii/S1388245703001743|journal=Clinical Neurophysiology|language=en|volume=114|issue=10|pages=1819–1826|doi=10.1016/S1388-2457(03)00174-3|issn=1388-2457|last1=Rau|first1=Cornelia|last2=Plewnia|first2=Christian|last3=Hummel|first3=Friedhelm|last4=Gerloff|first4=Christian|pmid=14499743|s2cid=39272563}}</ref> He earned his medical doctor in 2000 for his work on ''Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate: eine Studie langsamer Potentiale'' (Plastic changes through semantic classical conditioning and their electrocortical correlates: a study of slow potentials).<ref>{{Cite book|last=Hummel|first=Friedhelm C.|url=https://rds-tue.ibs-bw.de/link?kid=1158454910|title=Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate eine Studie langsamer Potentiale|date=2000|location=Tübingen}}</ref>


In 2003, he joined the [[National Institute of Neurological Disorders and Stroke|NINDS]] at the [[National Institutes of Health]] in [[Bethesda, Maryland|Bethesda]] supported by a Feodor Lynen grant from the [[Alexander von Humboldt Foundation]].<ref name="Fridman 747–758">{{Cite journal|last=Fridman|first=E. A.|date=2004-01-14|title=Reorganization of the human ipsilesional premotor cortex after stroke|url=https://academic.oup.com/brain/article-lookup/doi/10.1093/brain/awh082|journal=Brain|language=en|volume=127|issue=4|pages=747–758|doi=10.1093/brain/awh082|pmid=14749291|issn=1460-2156}}</ref><ref name="Hummel 490–499">{{Cite journal|last=Hummel|first=F.|date=2005-01-05|title=Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke|journal=Brain|language=en|volume=128|issue=3|pages=490–499|doi=10.1093/brain/awh369|pmid=15634731|issn=1460-2156|doi-access=free}}</ref> In 2005, he returned as researcher and medical resident to the Department of Neurology at Tübingen,<ref>{{Cite journal|last1=Gandiga|first1=Prateek C.|last2=Hummel|first2=Friedhelm C.|last3=Cohen|first3=Leonardo G.|date=2006-04-XX|title=Transcranial DC stimulation (tDCS): A tool for double-blind sham-controlled clinical studies in brain stimulation|url=https://linkinghub.elsevier.com/retrieve/pii/S1388245705005079|journal=Clinical Neurophysiology|language=en|volume=117|issue=4|pages=845–850|doi=10.1016/j.clinph.2005.12.003|pmid=16427357|s2cid=25934876}}</ref> before starting in 2006 at the [[University Medical Center Hamburg-Eppendorf]] in the same function.<ref>{{Cite journal|last1=Heise|first1=K.-F|last2=Gerloff|first2=C|last3=Hummel|first3=F|date=2007-09-XX|title=Nicht invasive kortikale Stimulation als adjuvante Therapie zur Unterstützung der funktionellen Erholung nach Schlaganfall|url=http://www.thieme-connect.de/DOI/DOI?10.1055/s-2007-963363|journal=Physioscience|language=de|volume=3|issue=3|pages=99–108|doi=10.1055/s-2007-963363|issn=1860-3092}}</ref> In 2006, he became the head of the Brain Imaging and Neurostimulation (BINS) Laboratory at Hamburg, followed by senior physician in 2007,<ref>{{Cite journal|last1=Nitsche|first1=Michael A.|last2=Cohen|first2=Leonardo G.|last3=Wassermann|first3=Eric M.|last4=Priori|first4=Alberto|last5=Lang|first5=Nicolas|last6=Antal|first6=Andrea|last7=Paulus|first7=Walter|last8=Hummel|first8=Friedhelm|last9=Boggio|first9=Paulo S.|last10=Fregni|first10=Felipe|last11=Pascual-Leone|first11=Alvaro|date=2008-07-XX|title=Transcranial direct current stimulation: State of the art 2008|url=https://linkinghub.elsevier.com/retrieve/pii/S1935861X08000405|journal=Brain Stimulation|language=en|volume=1|issue=3|pages=206–223|doi=10.1016/j.brs.2008.06.004|pmid=20633386|s2cid=16352598}}</ref><ref>{{Cite journal|date=2009-11-17|title=Brain Oscillatory Substrates of Visual Short-Term Memory Capacity|journal=Current Biology|language=en|volume=19|issue=21|pages=1846–1852|doi=10.1016/j.cub.2009.08.062|issn=0960-9822|last1=Sauseng|first1=Paul|last2=Klimesch|first2=Wolfgang|last3=Heise|first3=Kirstin F.|last4=Gruber|first4=Walter R.|last5=Holz|first5=Elisa|last6=Karim|first6=Ahmed A.|last7=Glennon|first7=Mark|last8=Gerloff|first8=Christian|last9=Birbaumer|first9=Niels|last10=Hummel|first10=Friedhelm C.|pmid=19913428|s2cid=13999952|doi-access=free}}</ref> co-chairman at the Centre for Sleep Medicine in 2008, senior neurologist in 2013, and vice-director of the Department of neurology in 2013.<ref>{{Cite web|last1=Hummel|first1=Friedhelm Christoph|last2=Gerloff|first2=Christian|date=2011|title=Zukunft der Neuromodulation|url=https://infoscience.epfl.ch/record/224097|access-date=2021-04-15|website=Handfunktionsstörungen in der Neurologie|language=en}}</ref><ref>{{Cite journal|last1=Lefaucheur|first1=Jean-Pascal|last2=André-Obadia|first2=Nathalie|last3=Antal|first3=Andrea|last4=Ayache|first4=Samar S.|last5=Baeken|first5=Chris|last6=Benninger|first6=David H.|last7=Cantello|first7=Roberto M.|last8=Cincotta|first8=Massimo|last9=de Carvalho|first9=Mamede|last10=De Ridder|first10=Dirk|last11=Devanne|first11=Hervé|date=2014-11-XX|title=Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)|url=https://linkinghub.elsevier.com/retrieve/pii/S138824571400296X|journal=Clinical Neurophysiology|language=en|volume=125|issue=11|pages=2150–2206|doi=10.1016/j.clinph.2014.05.021|pmid=25034472|s2cid=206798663}}</ref>
In 2003, he received a [[Feodor Lynen]] award from the [[Alexander von Humboldt Foundation]] to join Leonardo Cohen's Human Cortical Physiology and Neurorehabilitation Section ([[National Institute of Neurological Disorders and Stroke|NINDS]]) at the [[National Institutes of Health]] (NIH) at [[Bethesda, Maryland|Bethesda]].<ref name="Fridman 747–758">{{Cite journal|last=Fridman|first=E. A.|date=2004-01-14|title=Reorganization of the human ipsilesional premotor cortex after stroke|url=https://academic.oup.com/brain/article-lookup/doi/10.1093/brain/awh082|journal=Brain|language=en|volume=127|issue=4|pages=747–758|doi=10.1093/brain/awh082|pmid=14749291|issn=1460-2156}}</ref><ref name="Hummel 490–499">{{Cite journal|last=Hummel|first=F.|date=2005-01-05|title=Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke|journal=Brain|language=en|volume=128|issue=3|pages=490–499|doi=10.1093/brain/awh369|pmid=15634731|issn=1460-2156|doi-access=free}}</ref> There he worked on first successful application of tDCS in stroke patients.<ref>{{Cite journal|last=Hummel|first=Friedhelm C|last2=Cohen|first2=Leonardo G|date=August 2006|title=Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?|url=http://dx.doi.org/10.1016/s1474-4422(06)70525-7|journal=The Lancet Neurology|volume=5|issue=8|pages=708–712|doi=10.1016/s1474-4422(06)70525-7|issn=1474-4422}}</ref> In 2005, he returned as researcher and medical resident to the Department of Neurology at Tübingen,<ref>{{Cite journal|last1=Gandiga|first1=Prateek C.|last2=Hummel|first2=Friedhelm C.|last3=Cohen|first3=Leonardo G.|date=2006-04-XX|title=Transcranial DC stimulation (tDCS): A tool for double-blind sham-controlled clinical studies in brain stimulation|url=https://linkinghub.elsevier.com/retrieve/pii/S1388245705005079|journal=Clinical Neurophysiology|language=en|volume=117|issue=4|pages=845–850|doi=10.1016/j.clinph.2005.12.003|pmid=16427357|s2cid=25934876}}</ref> and, in 2006, at the [[University Medical Center Hamburg-Eppendorf]] to finish his residency.<ref>{{Cite journal|last1=Heise|first1=K.-F|last2=Gerloff|first2=C|last3=Hummel|first3=F|date=2007-09-XX|title=Nicht invasive kortikale Stimulation als adjuvante Therapie zur Unterstützung der funktionellen Erholung nach Schlaganfall|url=http://www.thieme-connect.de/DOI/DOI?10.1055/s-2007-963363|journal=Physioscience|language=de|volume=3|issue=3|pages=99–108|doi=10.1055/s-2007-963363|issn=1860-3092}}</ref> In 2006, he founded the Brain Imaging and Neurostimulation (BINS) Laboratory at Hamburg, became a certified in 2007,<ref>{{Cite journal|last1=Nitsche|first1=Michael A.|last2=Cohen|first2=Leonardo G.|last3=Wassermann|first3=Eric M.|last4=Priori|first4=Alberto|last5=Lang|first5=Nicolas|last6=Antal|first6=Andrea|last7=Paulus|first7=Walter|last8=Hummel|first8=Friedhelm|last9=Boggio|first9=Paulo S.|last10=Fregni|first10=Felipe|last11=Pascual-Leone|first11=Alvaro|date=2008-07-XX|title=Transcranial direct current stimulation: State of the art 2008|url=https://linkinghub.elsevier.com/retrieve/pii/S1935861X08000405|journal=Brain Stimulation|language=en|volume=1|issue=3|pages=206–223|doi=10.1016/j.brs.2008.06.004|pmid=20633386|s2cid=16352598}}</ref><ref>{{Cite journal|date=2009-11-17|title=Brain Oscillatory Substrates of Visual Short-Term Memory Capacity|journal=Current Biology|language=en|volume=19|issue=21|pages=1846–1852|doi=10.1016/j.cub.2009.08.062|issn=0960-9822|last1=Sauseng|first1=Paul|last2=Klimesch|first2=Wolfgang|last3=Heise|first3=Kirstin F.|last4=Gruber|first4=Walter R.|last5=Holz|first5=Elisa|last6=Karim|first6=Ahmed A.|last7=Glennon|first7=Mark|last8=Gerloff|first8=Christian|last9=Birbaumer|first9=Niels|last10=Hummel|first10=Friedhelm C.|pmid=19913428|s2cid=13999952|doi-access=free}}</ref> co-chairman at the Centre for Sleep Medicine in 2008, senior neurologist in 2013, and vice-director of the Department of neurology in 2013.<ref>{{Cite web|last1=Hummel|first1=Friedhelm Christoph|last2=Gerloff|first2=Christian|date=2011|title=Zukunft der Neuromodulation|url=https://infoscience.epfl.ch/record/224097|access-date=2021-04-15|website=Handfunktionsstörungen in der Neurologie|language=en}}</ref><ref>{{Cite journal|last1=Lefaucheur|first1=Jean-Pascal|last2=André-Obadia|first2=Nathalie|last3=Antal|first3=Andrea|last4=Ayache|first4=Samar S.|last5=Baeken|first5=Chris|last6=Benninger|first6=David H.|last7=Cantello|first7=Roberto M.|last8=Cincotta|first8=Massimo|last9=de Carvalho|first9=Mamede|last10=De Ridder|first10=Dirk|last11=Devanne|first11=Hervé|date=2014-11-XX|title=Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)|url=https://linkinghub.elsevier.com/retrieve/pii/S138824571400296X|journal=Clinical Neurophysiology|language=en|volume=125|issue=11|pages=2150–2206|doi=10.1016/j.clinph.2014.05.021|pmid=25034472|s2cid=206798663}}</ref>


Since 2016 he holds the Defitech Chair of Clinical Neuroengineering as full professor, is the director of the Centre for Neuroprosthetics and the Brain Mind Institute, both at EPFL,<ref name=":0" /><ref name=":1" /> and is associate professor of clinical neuroscience at the University of Geneva.<ref name=":2" />
Since 2016 he holds the Defitech Chair of Clinical Neuroengineering as full professor, is the director of the Centre for Neuroprosthetics and the Brain Mind Institute, both at EPFL,<ref name=":0" /><ref name=":1" /> and is associate professor of clinical neuroscience at the University of Geneva.<ref name=":2" />


== Research ==
== Research ==
Hummel's research targets the fields of [[Systems neuroscience|systems]] and [[Translational neuroscience|translational clinical neuroscience]] with 3 main focus. First focus is on using multimodal imaging and behavioral measures to study neuroplasticity, neuronal control of sensorimotor functions, learning, and cognitive functions in healthy and neurological disorders, such as stroke, MCI or TBI. The second main focus is on developing innovative non-invasive interventional strategies based on neurotechnology,<ref>{{Cite journal|last=Coscia|first=Martina|last2=Wessel|first2=Maximilian J|last3=Chaudary|first3=Ujwal|last4=Millán|first4=José del R|last5=Micera|first5=Silvestro|last6=Guggisberg|first6=Adrian|last7=Vuadens|first7=Philippe|last8=Donoghue|first8=John|last9=Birbaumer|first9=Niels|last10=Hummel|first10=Friedhelm C|date=2019-07-01|title=Neurotechnology-aided interventions for upper limb motor rehabilitation in severe chronic stroke|url=https://doi.org/10.1093/brain/awz181|journal=Brain|volume=142|issue=8|pages=2182–2197|doi=10.1093/brain/awz181|issn=0006-8950|pmc=PMC6658861|pmid=31257411}}</ref><ref>{{Cite journal|last=Micera|first=Silvestro|last2=Caleo|first2=Matteo|last3=Chisari|first3=Carmelo|last4=Hummel|first4=Friedhelm C.|last5=Pedrocchi|first5=Alessandra|date=2020-02-19|title=Advanced Neurotechnologies for the Restoration of Motor Function|url=https://www.cell.com/neuron/abstract/S0896-6273(20)30066-0|journal=Neuron|language=English|volume=105|issue=4|pages=604–620|doi=10.1016/j.neuron.2020.01.039|issn=0896-6273|pmid=32078796}}</ref><ref>{{Cite journal|last=Raffin|first=Estelle|last2=Salamanca-Giron|first2=Roberto F.|last3=Hummel|first3=Friedhelm Christoph|date=2020-01-01|title=Perspectives: Hemianopia—Toward Novel Treatment Options Based on Oscillatory Activity?|url=https://doi.org/10.1177/1545968319893286|journal=Neurorehabilitation and Neural Repair|language=en|volume=34|issue=1|pages=13–25|doi=10.1177/1545968319893286|issn=1545-9683}}</ref> such as brain stimulation<ref>{{Cite journal|last=Wessel|first=Maximilian J.|last2=Draaisma|first2=Laurijn R.|last3=de Boer|first3=Anne F. W.|last4=Park|first4=Chang-hyun|last5=Maceira-Elvira|first5=Pablo|last6=Durand-Ruel|first6=Manon|last7=Koch|first7=Philipp J.|last8=Morishita|first8=Takuya|last9=Hummel|first9=Friedhelm C.|date=2020-07-08|title=Cerebellar transcranial alternating current stimulation in the gamma range applied during the acquisition of a novel motor skill|url=https://www.nature.com/articles/s41598-020-68028-9|journal=Scientific Reports|language=en|volume=10|issue=1|pages=11217|doi=10.1038/s41598-020-68028-9|issn=2045-2322|pmc=PMC7343806|pmid=32641706}}</ref><ref>{{Cite journal|last=Salamanca-giron|first=Roberto F.|last2=Raffin|first2=Estelle|last3=Zandvliet|first3=Sarah B.|last4=Seeber|first4=Martin|last5=Michel|first5=Christoph M.|last6=Sauseng|first6=Paul|last7=Huxlin|first7=Krystel R.|last8=Hummel|first8=Friedhelm C.|date=2021-10-15|title=Enhancing visual motion discrimination by desynchronizing bifocal oscillatory activity|url=https://www.sciencedirect.com/science/article/pii/S1053811921005759|journal=NeuroImage|language=en|volume=240|pages=118299|doi=10.1016/j.neuroimage.2021.118299|issn=1053-8119}}</ref> to support patients residual functions and enhance recovery.<ref>{{Cite journal|last=Raffin|first=Estelle|last2=Hummel|first2=Friedhelm C.|date=2018-08-01|title=Restoring Motor Functions After Stroke: Multiple Approaches and Opportunities|url=https://doi.org/10.1177/1073858417737486|journal=The Neuroscientist|language=en|volume=24|issue=4|pages=400–416|doi=10.1177/1073858417737486|issn=1073-8584}}</ref><ref>{{Cite journal|last=Wessel|first=Maximilian J.|last2=Hummel|first2=Friedhelm C.|date=2018-06-01|title=Non-invasive Cerebellar Stimulation: a Promising Approach for Stroke Recovery?|url=https://doi.org/10.1007/s12311-017-0906-1|journal=The Cerebellum|language=en|volume=17|issue=3|pages=359–371|doi=10.1007/s12311-017-0906-1|issn=1473-4230}}</ref> He has been involved in the application of non-invasive brain stimulation in stroke.<ref>{{Cite journal|last=Hummel|first=F.|date=2005-01-05|title=Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke|url=https://doi.org/10.1093/brain/awh369|journal=Brain|volume=128|issue=3|pages=490–499|doi=10.1093/brain/awh369|issn=1460-2156}}</ref><ref>{{Cite journal|last=Hummel|first=Friedhelm C.|last2=Cohen|first2=Leonardo G.|date=2006-08-01|title=Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?|url=https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(06)70525-7/abstract|journal=The Lancet Neurology|language=English|volume=5|issue=8|pages=708–712|doi=10.1016/S1474-4422(06)70525-7|issn=1474-4422|pmid=16857577}}</ref> The further focus lays on using multimodal imaging to predict outcome and course of recovery after a stroke (Koch et al. 2021 Brain; Egger et al. 2021 Stroke), a prerequisite for personalized treatment strategies.<ref>{{Cite journal|last=Koch|first=Philipp J|last2=Park|first2=Chang-Hyun|last3=Girard|first3=Gabriel|last4=Beanato|first4=Elena|last5=Egger|first5=Philip|last6=Evangelista|first6=Giorgia Giulia|last7=Lee|first7=Jungsoo|last8=Wessel|first8=Maximilian J|last9=Morishita|first9=Takuya|last10=Koch|first10=Giacomo|last11=Thiran|first11=Jean-Philippe|date=2021-07-01|title=The structural connectome and motor recovery after stroke: predicting natural recovery|url=https://doi.org/10.1093/brain/awab082|journal=Brain|volume=144|issue=7|pages=2107–2119|doi=10.1093/brain/awab082|issn=0006-8950|pmc=PMC8370413|pmid=34237143}}</ref><ref>{{Cite journal|last=Egger|first=Philip|last2=Evangelista|first2=Giorgia G.|last3=Koch|first3=Philipp J.|last4=Park|first4=Chang-Hyun|last5=Levin-Gleba|first5=Laura|last6=Girard|first6=Gabriel|last7=Beanato|first7=Elena|last8=Lee|first8=Jungsoo|last9=Choirat|first9=Christine|last10=Guggisberg|first10=Adrian G.|last11=Kim|first11=Yun-Hee|date=2021-06-01|title=Disconnectomics of the Rich Club Impacts Motor Recovery After Stroke|url=https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.031541|journal=Stroke|volume=52|issue=6|pages=2115–2124|doi=10.1161/STROKEAHA.120.031541}}</ref>
Hummel's research is in [[Systems neuroscience|systems]] and [[translational neuroscience]]. His focus is on neuroplasticity, neuronal control of sensorimotor function, motor skill acquisition and learning, and healthy aging. He is interested in [[stroke]] in the acute and chronic phase, [[neurofibromatosis]] and extrapyramidal movement disorders like [[dystonia]],<ref>{{Cite journal|last1=Hummel|first1=Friedhelm C|last2=Cohen|first2=Leonardo G|date=2006-08-XX|title=Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?|url=https://linkinghub.elsevier.com/retrieve/pii/S1474442206705257|journal=The Lancet Neurology|language=en|volume=5|issue=8|pages=708–712|doi=10.1016/S1474-4422(06)70525-7|pmid=16857577|s2cid=9509765}}</ref> particularly functional reorganization and recovery after focal brain lesions by using multimodal systems neurosciences approaches including [[neuroimaging]], brain stimulation and psychophysical and clinical evaluations.<ref name="Hummel 490–499"/><ref>{{Cite journal|last1=Sauseng|first1=Paul|last2=Klimesch|first2=Wolfgang|last3=Heise|first3=Kirstin F.|last4=Gruber|first4=Walter R.|last5=Holz|first5=Elisa|last6=Karim|first6=Ahmed A.|last7=Glennon|first7=Mark|last8=Gerloff|first8=Christian|last9=Birbaumer|first9=Niels|last10=Hummel|first10=Friedhelm C.|date=2009-11-XX|title=Brain Oscillatory Substrates of Visual Short-Term Memory Capacity|journal=Current Biology|language=en|volume=19|issue=21|pages=1846–1852|doi=10.1016/j.cub.2009.08.062|pmid=19913428|s2cid=13999952|doi-access=free}}</ref><ref>{{Cite journal|date=2005-12-01|title=Transcallosal inhibition in chronic subcortical stroke|url=https://www.sciencedirect.com/science/article/abs/pii/S1053811905004805|journal=NeuroImage|language=en|volume=28|issue=4|pages=940–946|doi=10.1016/j.neuroimage.2005.06.033|issn=1053-8119|last1=Duque|first1=Julie|last2=Hummel|first2=Friedhelm|last3=Celnik|first3=Pablo|last4=Murase|first4=Nagako|last5=Mazzocchio|first5=Riccardo|last6=Cohen|first6=Leonardo G.|pmid=16084737|s2cid=39285099}}</ref>

He investigates the fundamental mechanism of healthy aging and functional regeneration after focal brain lesions, such as after stroke or traumatic brain injury. He is also interested in clinical rehabilitation through modulation, such as by non-invasive brain stimulation.<ref name="Fridman 747–758"/><ref>{{Cite journal|last1=Sauseng|first1=P.|last2=Hoppe|first2=J.|last3=Klimesch|first3=W.|last4=Gerloff|first4=C.|last5=Hummel|first5=F. C.|date=2007|title=Dissociation of sustained attention from central executive functions: local activity and interregional connectivity in the theta range|url=https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1460-9568.2006.05286.x|journal=European Journal of Neuroscience|language=en|volume=25|issue=2|pages=587–593|doi=10.1111/j.1460-9568.2006.05286.x|pmid=17284201|s2cid=3487768|issn=1460-9568}}</ref>


His research was featured in news outlets such as [[Neue Zürcher Zeitung|NZZ]],<ref>{{Cite web|last=Geiser|first=Eveline|date=2021-07-15|title=Wo Ärzte abwarten müssen, kann künstliche Intelligenz eine Prognose stellen|url=https://www.nzz.ch/wissenschaft/wo-aerzte-abwarten-muessen-kann-kuenstliche-intelligenz-eine-prognose-stellen-ld.1634821|url-status=live|access-date=2021-09-01|website=Neue Zürcher Zeitung}}</ref> [[Le Nouvelliste (Valais)|Le Nouvelliste]], [[Physics World]],<ref>{{Cite web|date=2021-07-13|title=Mapping the brain's neural connections can predict recovery after stroke|url=https://physicsworld.com/mapping-the-brains-neural-connections-can-predict-recovery-after-stroke/|access-date=2021-09-01|website=Physics World|language=en-GB}}</ref> [[Der Spiegel]],<ref>{{Cite news|last=SPIEGEL|first=Susanne Schäfer, DER|title=Warum ein Schlag auf den Musikknochen so weh tut|url=https://www.spiegel.de/gesundheit/diagnose/warum-ein-schlag-auf-den-musikknochen-so-weh-tut-a-1028465.html|access-date=2021-09-01|newspaper=Der Spiegel|date=23 April 2015|language=de}}</ref> and [[Focus (German magazine)|Focus]].<ref>{{Cite web|last=Online|first=FOCUS|title=Stimulation von Hirnarealen|url=https://www.focus.de/wissen/mensch/intelligenz/gehirndoping-mit-strom-stimulation-von-hirnarealen_id_4047440.html|access-date=2021-09-01|website=FOCUS Online|language=de}}</ref>
His research was featured in news outlets such as [[Neue Zürcher Zeitung|NZZ]],<ref>{{Cite web|last=Geiser|first=Eveline|date=2021-07-15|title=Wo Ärzte abwarten müssen, kann künstliche Intelligenz eine Prognose stellen|url=https://www.nzz.ch/wissenschaft/wo-aerzte-abwarten-muessen-kann-kuenstliche-intelligenz-eine-prognose-stellen-ld.1634821|url-status=live|access-date=2021-09-01|website=Neue Zürcher Zeitung}}</ref> [[Le Nouvelliste (Valais)|Le Nouvelliste]], [[Physics World]],<ref>{{Cite web|date=2021-07-13|title=Mapping the brain's neural connections can predict recovery after stroke|url=https://physicsworld.com/mapping-the-brains-neural-connections-can-predict-recovery-after-stroke/|access-date=2021-09-01|website=Physics World|language=en-GB}}</ref> [[Der Spiegel]],<ref>{{Cite news|last=SPIEGEL|first=Susanne Schäfer, DER|title=Warum ein Schlag auf den Musikknochen so weh tut|url=https://www.spiegel.de/gesundheit/diagnose/warum-ein-schlag-auf-den-musikknochen-so-weh-tut-a-1028465.html|access-date=2021-09-01|newspaper=Der Spiegel|date=23 April 2015|language=de}}</ref> and [[Focus (German magazine)|Focus]].<ref>{{Cite web|last=Online|first=FOCUS|title=Stimulation von Hirnarealen|url=https://www.focus.de/wissen/mensch/intelligenz/gehirndoping-mit-strom-stimulation-von-hirnarealen_id_4047440.html|access-date=2021-09-01|website=FOCUS Online|language=de}}</ref>

Revision as of 10:53, 19 January 2022

Professor
Friedhelm Hummel
Friedhelm Hummel in 2016
Born1969 (age 54–55)
Laichingen, Germany
CitizenshipGermany
Known forNeurorehabilitation
AwardsFelgenhauer Symposiums Prize
Prize of the German Society of Neurotraumatology and Clinical Neurorehabilitation
Dr. Martini Prize
Academic background
EducationMedicine
Alma materUniversity of Tübingen
University of Bordeaux
ThesisElastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate: eine Studie langsamer Potentiale (2000)
Academic work
DisciplineNeuroscience
Sub-disciplineNeurorehabilitation
InstitutionsEPFL (École Polytechnique Fédérale de Lausanne)
Main interestsStroke recovery
Motor control
Neuroplasticity
Non-invasive brain stimulation
Structural and functional neuroimaging
Websitehttps://www.epfl.ch/labs/hummel-lab/

Friedhelm Hummel (born 1969 in Laichingen, Germany) is a German neuroscientist and neurologist. As a full professor he holds the Defitech Chair of Clinical Neuroengineering at École Polytechnique Fédérale de Lausanne, the head of the Hummel Laboratory at EPFL's School of Life Sciences.[1][2] He also is an associate professor of clinical neuroscience at the University of Geneva.[3]

Career

Hummel studied medicine at University of Tübingen and at Bordeaux Segalen University and graduated in 1998. He then joined the Department of Neurology at University of Tübingen as a medical resident and researcher.[4] He earned his medical doctor in 2000 for his work on Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate: eine Studie langsamer Potentiale (Plastic changes through semantic classical conditioning and their electrocortical correlates: a study of slow potentials).[5]

In 2003, he received a Feodor Lynen award from the Alexander von Humboldt Foundation to join Leonardo Cohen's Human Cortical Physiology and Neurorehabilitation Section (NINDS) at the National Institutes of Health (NIH) at Bethesda.[6][7] There he worked on first successful application of tDCS in stroke patients.[8] In 2005, he returned as researcher and medical resident to the Department of Neurology at Tübingen,[9] and, in 2006, at the University Medical Center Hamburg-Eppendorf to finish his residency.[10] In 2006, he founded the Brain Imaging and Neurostimulation (BINS) Laboratory at Hamburg, became a certified in 2007,[11][12] co-chairman at the Centre for Sleep Medicine in 2008, senior neurologist in 2013, and vice-director of the Department of neurology in 2013.[13][14]

Since 2016 he holds the Defitech Chair of Clinical Neuroengineering as full professor, is the director of the Centre for Neuroprosthetics and the Brain Mind Institute, both at EPFL,[1][2] and is associate professor of clinical neuroscience at the University of Geneva.[3]

Research

Hummel's research targets the fields of systems and translational clinical neuroscience with 3 main focus. First focus is on using multimodal imaging and behavioral measures to study neuroplasticity, neuronal control of sensorimotor functions, learning, and cognitive functions in healthy and neurological disorders, such as stroke, MCI or TBI. The second main focus is on developing innovative non-invasive interventional strategies based on neurotechnology,[15][16][17] such as brain stimulation[18][19] to support patients residual functions and enhance recovery.[20][21] He has been involved in the application of non-invasive brain stimulation in stroke.[22][23] The further focus lays on using multimodal imaging to predict outcome and course of recovery after a stroke (Koch et al. 2021 Brain; Egger et al. 2021 Stroke), a prerequisite for personalized treatment strategies.[24][25]

His research was featured in news outlets such as NZZ,[26] Le Nouvelliste, Physics World,[27] Der Spiegel,[28] and Focus.[29]

Distinctions

Hummel is the recipient of the 2015 Felgenhauer Symposiums Prize of the German Neurological Society and the Felgenhauer Foundation;[30] the 2013 prize of the German Society of Neurotraumatology and Clinical Neurorehabilitation;[31] the 2010 Dr. Martini Prize;[32] the 2005 Susanne Klein-Vogelbach Prize;[33] 2005 Fellows Award for Research Excellence by the National Institutes of Health; and the 2003 Feodor Lynen Research Fellowship Award by the Alexander von Humboldt Foundation.[31]

He is a member of the German Neurological Society,[34] the Society for Neuroscience, and the Society for the Neural Control of Movement.[35]

Selected works

References

  1. ^ a b "Hummel Lab". www.epfl.ch. Retrieved 2021-04-14.
  2. ^ a b "Brexit: closer cooperation with the UK cannot replace participation in Horizon 2020 | ETH-Board". www.ethrat.ch. Retrieved 2021-04-15.
  3. ^ a b "Friedhelm Hummel | Campus Biotech". www.campusbiotech.ch. Retrieved 2021-04-15.
  4. ^ Rau, Cornelia; Plewnia, Christian; Hummel, Friedhelm; Gerloff, Christian (2003-10-01). "Event-related desynchronization and excitability of the ipsilateral motor cortex during simple self-paced finger movements". Clinical Neurophysiology. 114 (10): 1819–1826. doi:10.1016/S1388-2457(03)00174-3. ISSN 1388-2457. PMID 14499743. S2CID 39272563.
  5. ^ Hummel, Friedhelm C. (2000). Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate eine Studie langsamer Potentiale. Tübingen.{{cite book}}: CS1 maint: location missing publisher (link)
  6. ^ Fridman, E. A. (2004-01-14). "Reorganization of the human ipsilesional premotor cortex after stroke". Brain. 127 (4): 747–758. doi:10.1093/brain/awh082. ISSN 1460-2156. PMID 14749291.
  7. ^ Hummel, F. (2005-01-05). "Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke". Brain. 128 (3): 490–499. doi:10.1093/brain/awh369. ISSN 1460-2156. PMID 15634731.
  8. ^ Hummel, Friedhelm C; Cohen, Leonardo G (August 2006). "Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?". The Lancet Neurology. 5 (8): 708–712. doi:10.1016/s1474-4422(06)70525-7. ISSN 1474-4422.
  9. ^ Gandiga, Prateek C.; Hummel, Friedhelm C.; Cohen, Leonardo G. (2006-04-XX). "Transcranial DC stimulation (tDCS): A tool for double-blind sham-controlled clinical studies in brain stimulation". Clinical Neurophysiology. 117 (4): 845–850. doi:10.1016/j.clinph.2005.12.003. PMID 16427357. S2CID 25934876. {{cite journal}}: Check date values in: |date= (help)
  10. ^ Heise, K.-F; Gerloff, C; Hummel, F (2007-09-XX). "Nicht invasive kortikale Stimulation als adjuvante Therapie zur Unterstützung der funktionellen Erholung nach Schlaganfall". Physioscience (in German). 3 (3): 99–108. doi:10.1055/s-2007-963363. ISSN 1860-3092. {{cite journal}}: Check date values in: |date= (help)
  11. ^ Nitsche, Michael A.; Cohen, Leonardo G.; Wassermann, Eric M.; Priori, Alberto; Lang, Nicolas; Antal, Andrea; Paulus, Walter; Hummel, Friedhelm; Boggio, Paulo S.; Fregni, Felipe; Pascual-Leone, Alvaro (2008-07-XX). "Transcranial direct current stimulation: State of the art 2008". Brain Stimulation. 1 (3): 206–223. doi:10.1016/j.brs.2008.06.004. PMID 20633386. S2CID 16352598. {{cite journal}}: Check date values in: |date= (help)
  12. ^ Sauseng, Paul; Klimesch, Wolfgang; Heise, Kirstin F.; Gruber, Walter R.; Holz, Elisa; Karim, Ahmed A.; Glennon, Mark; Gerloff, Christian; Birbaumer, Niels; Hummel, Friedhelm C. (2009-11-17). "Brain Oscillatory Substrates of Visual Short-Term Memory Capacity". Current Biology. 19 (21): 1846–1852. doi:10.1016/j.cub.2009.08.062. ISSN 0960-9822. PMID 19913428. S2CID 13999952.
  13. ^ Hummel, Friedhelm Christoph; Gerloff, Christian (2011). "Zukunft der Neuromodulation". Handfunktionsstörungen in der Neurologie. Retrieved 2021-04-15.
  14. ^ Lefaucheur, Jean-Pascal; André-Obadia, Nathalie; Antal, Andrea; Ayache, Samar S.; Baeken, Chris; Benninger, David H.; Cantello, Roberto M.; Cincotta, Massimo; de Carvalho, Mamede; De Ridder, Dirk; Devanne, Hervé (2014-11-XX). "Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)". Clinical Neurophysiology. 125 (11): 2150–2206. doi:10.1016/j.clinph.2014.05.021. PMID 25034472. S2CID 206798663. {{cite journal}}: Check date values in: |date= (help)
  15. ^ Coscia, Martina; Wessel, Maximilian J; Chaudary, Ujwal; Millán, José del R; Micera, Silvestro; Guggisberg, Adrian; Vuadens, Philippe; Donoghue, John; Birbaumer, Niels; Hummel, Friedhelm C (2019-07-01). "Neurotechnology-aided interventions for upper limb motor rehabilitation in severe chronic stroke". Brain. 142 (8): 2182–2197. doi:10.1093/brain/awz181. ISSN 0006-8950. PMC 6658861. PMID 31257411.{{cite journal}}: CS1 maint: PMC format (link)
  16. ^ Micera, Silvestro; Caleo, Matteo; Chisari, Carmelo; Hummel, Friedhelm C.; Pedrocchi, Alessandra (2020-02-19). "Advanced Neurotechnologies for the Restoration of Motor Function". Neuron. 105 (4): 604–620. doi:10.1016/j.neuron.2020.01.039. ISSN 0896-6273. PMID 32078796.
  17. ^ Raffin, Estelle; Salamanca-Giron, Roberto F.; Hummel, Friedhelm Christoph (2020-01-01). "Perspectives: Hemianopia—Toward Novel Treatment Options Based on Oscillatory Activity?". Neurorehabilitation and Neural Repair. 34 (1): 13–25. doi:10.1177/1545968319893286. ISSN 1545-9683.
  18. ^ Wessel, Maximilian J.; Draaisma, Laurijn R.; de Boer, Anne F. W.; Park, Chang-hyun; Maceira-Elvira, Pablo; Durand-Ruel, Manon; Koch, Philipp J.; Morishita, Takuya; Hummel, Friedhelm C. (2020-07-08). "Cerebellar transcranial alternating current stimulation in the gamma range applied during the acquisition of a novel motor skill". Scientific Reports. 10 (1): 11217. doi:10.1038/s41598-020-68028-9. ISSN 2045-2322. PMC 7343806. PMID 32641706.{{cite journal}}: CS1 maint: PMC format (link)
  19. ^ Salamanca-giron, Roberto F.; Raffin, Estelle; Zandvliet, Sarah B.; Seeber, Martin; Michel, Christoph M.; Sauseng, Paul; Huxlin, Krystel R.; Hummel, Friedhelm C. (2021-10-15). "Enhancing visual motion discrimination by desynchronizing bifocal oscillatory activity". NeuroImage. 240: 118299. doi:10.1016/j.neuroimage.2021.118299. ISSN 1053-8119.
  20. ^ Raffin, Estelle; Hummel, Friedhelm C. (2018-08-01). "Restoring Motor Functions After Stroke: Multiple Approaches and Opportunities". The Neuroscientist. 24 (4): 400–416. doi:10.1177/1073858417737486. ISSN 1073-8584.
  21. ^ Wessel, Maximilian J.; Hummel, Friedhelm C. (2018-06-01). "Non-invasive Cerebellar Stimulation: a Promising Approach for Stroke Recovery?". The Cerebellum. 17 (3): 359–371. doi:10.1007/s12311-017-0906-1. ISSN 1473-4230.
  22. ^ Hummel, F. (2005-01-05). "Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke". Brain. 128 (3): 490–499. doi:10.1093/brain/awh369. ISSN 1460-2156.
  23. ^ Hummel, Friedhelm C.; Cohen, Leonardo G. (2006-08-01). "Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?". The Lancet Neurology. 5 (8): 708–712. doi:10.1016/S1474-4422(06)70525-7. ISSN 1474-4422. PMID 16857577.
  24. ^ Koch, Philipp J; Park, Chang-Hyun; Girard, Gabriel; Beanato, Elena; Egger, Philip; Evangelista, Giorgia Giulia; Lee, Jungsoo; Wessel, Maximilian J; Morishita, Takuya; Koch, Giacomo; Thiran, Jean-Philippe (2021-07-01). "The structural connectome and motor recovery after stroke: predicting natural recovery". Brain. 144 (7): 2107–2119. doi:10.1093/brain/awab082. ISSN 0006-8950. PMC 8370413. PMID 34237143.{{cite journal}}: CS1 maint: PMC format (link)
  25. ^ Egger, Philip; Evangelista, Giorgia G.; Koch, Philipp J.; Park, Chang-Hyun; Levin-Gleba, Laura; Girard, Gabriel; Beanato, Elena; Lee, Jungsoo; Choirat, Christine; Guggisberg, Adrian G.; Kim, Yun-Hee (2021-06-01). "Disconnectomics of the Rich Club Impacts Motor Recovery After Stroke". Stroke. 52 (6): 2115–2124. doi:10.1161/STROKEAHA.120.031541.
  26. ^ Geiser, Eveline (2021-07-15). "Wo Ärzte abwarten müssen, kann künstliche Intelligenz eine Prognose stellen". Neue Zürcher Zeitung. Retrieved 2021-09-01.{{cite web}}: CS1 maint: url-status (link)
  27. ^ "Mapping the brain's neural connections can predict recovery after stroke". Physics World. 2021-07-13. Retrieved 2021-09-01.
  28. ^ SPIEGEL, Susanne Schäfer, DER (23 April 2015). "Warum ein Schlag auf den Musikknochen so weh tut". Der Spiegel (in German). Retrieved 2021-09-01.{{cite news}}: CS1 maint: multiple names: authors list (link)
  29. ^ Online, FOCUS. "Stimulation von Hirnarealen". FOCUS Online (in German). Retrieved 2021-09-01.
  30. ^ "Awards (2014 - 2015)". hahn-institute.de. Retrieved 2021-04-15.
  31. ^ a b "Third congress on NeuroRehabilitation and Neural Repair" (PDF). NeuroRehabilitation and Neural Repair. Retrieved 2021-04-15.{{cite web}}: CS1 maint: url-status (link)
  32. ^ "Dr. Martini-Preis | Dr.-Martini-Stiftung". 2016-10-23. Archived from the original on 2016-10-23. Retrieved 2021-04-15.
  33. ^ "SKV-Preis". FBL FUNCTIONAL KINETICS (in German). Retrieved 2021-04-15.
  34. ^ "Preise und Ehrungen der DGN auf dem Kongress 2015 - Deutsche Gesellschaft für Neurologie e. V." Deutsche Gesellschaft für Neurologie (in German). Retrieved 2021-04-15.{{cite web}}: CS1 maint: url-status (link)
  35. ^ "29th NCM Annual Meeting" (PDF). Neural Control of Movement Society. Retrieved 2021-04-15.{{cite web}}: CS1 maint: url-status (link)
Retrieved from "https://en.wikipedia.org/w/index.php?title=Friedhelm_Hummel&oldid=1066643145"