Hypertrophic scar: Difference between revisions

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Added findings from a 2021 Cochrane Review (Silicone gel sheeting for treating hypertrophic scars) to the "Prevention and treatment" section.
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It is not possible to completely prevent hypertrophic scars, so those with a history of them should inform their doctor or surgeon if they need surgery.
It is not possible to completely prevent hypertrophic scars, so those with a history of them should inform their doctor or surgeon if they need surgery.


A 2021 [[systematic review]] brought together evidence from different studies that investigated using silicone gel sheeting to treat hypertrophic scars. The authors found 13 studies with a total of 468 participants that looked at this research question. A lot of different treatments were included but it was uncertain whether silicone gel sheets were more effective than most of these. Silicone gel sheets may improve the appearance of scars slightly compared with applying onion extract, and may reduce pain compared with no treatment with silicone gel sheets or pressure garments.<ref>{{Cite journal |last=Jiang |first=Qingling |last2=Chen |first2=Junjie |last3=Tian |first3=Fan |last4=Liu |first4=Zhenmi |date=2021-09-26 |editor-last=Cochrane Wounds Group |title=Silicone gel sheeting for treating hypertrophic scars |url=http://doi.wiley.com/10.1002/14651858.CD013357.pub2 |journal=Cochrane Database of Systematic Reviews |language=en |volume=2021 |issue=9 |doi=10.1002/14651858.CD013357.pub2 |pmc=PMC8464654 |pmid=34564840}}</ref>
Scar therapies, such as [[cryosurgery]], may speed up the process of change from a hypertrophic scar to a flatter, paler one.<ref>{{Cite journal|last1=Zouboulis|first1=C. C.|last2=Blume|first2=U.|last3=Büttner|first3=P.|last4=Orfanos|first4=C. E.|date=September 1993|title=Outcomes of cryosurgery in keloids and hypertrophic scars. A prospective consecutive trial of case series|url=https://pubmed.ncbi.nlm.nih.gov/8363398/|journal=Archives of Dermatology|volume=129|issue=9|pages=1146–1151|doi=10.1001/archderm.1993.01680300074011|issn=0003-987X|pmid=8363398}}</ref>

Scar therapies, such as [[cryosurgery]], may speed up the process of change from a hypertrophic scar to a flatter, paler one.<ref>{{Cite journal|last1=Zouboulis|first1=C. C.|last2=Blume|first2=U.|last3=Büttner|first3=P.|last4=Orfanos|first4=C. E.|date=September 1993|title=Outcomes of cryosurgery in keloids and hypertrophic scars. A prospective consecutive trial of case series|url=https://pubmed.ncbi.nlm.nih.gov/8363398/|journal=Archives of Dermatology|volume=129|issue=9|pages=1146–1151|doi=10.1001/archderm.1993.01680300074011|issn=0003-987X|pmid=8363398}}</ref>


Early hypertrophic scar should be treated with applied pressure and massage in the first 1.5–3 months. If necessary, silicone therapy should be applied later. Ongoing hypertrophy may be treated with corticosteroids injections.<ref>{{Cite journal|last1=Juckett|first1=Gregory|last2=Hartman-Adams|first2=Holly|date=2009-08-01|title=Management of keloids and hypertrophic scars|url=https://pubmed.ncbi.nlm.nih.gov/19621835|journal=American Family Physician|volume=80|issue=3|pages=253–260|issn=1532-0650|pmid=19621835}}</ref> Surgical revision may be considered after 1 year.<ref>{{Cite journal|last1=Cooper|first1=Jason S.|last2=Lee|first2=Bernard T.|date=December 2009|title=Treatment of facial scarring: lasers, filler, and nonoperative techniques|url=https://pubmed.ncbi.nlm.nih.gov/20024872|journal=Facial Plastic Surgery |volume=25|issue=5|pages=311–315|doi=10.1055/s-0029-1243079|issn=1098-8793|pmid=20024872}}</ref>
Early hypertrophic scar should be treated with applied pressure and massage in the first 1.5–3 months. If necessary, silicone therapy should be applied later. Ongoing hypertrophy may be treated with corticosteroids injections.<ref>{{Cite journal|last1=Juckett|first1=Gregory|last2=Hartman-Adams|first2=Holly|date=2009-08-01|title=Management of keloids and hypertrophic scars|url=https://pubmed.ncbi.nlm.nih.gov/19621835|journal=American Family Physician|volume=80|issue=3|pages=253–260|issn=1532-0650|pmid=19621835}}</ref> Surgical revision may be considered after 1 year.<ref>{{Cite journal|last1=Cooper|first1=Jason S.|last2=Lee|first2=Bernard T.|date=December 2009|title=Treatment of facial scarring: lasers, filler, and nonoperative techniques|url=https://pubmed.ncbi.nlm.nih.gov/20024872|journal=Facial Plastic Surgery |volume=25|issue=5|pages=311–315|doi=10.1055/s-0029-1243079|issn=1098-8793|pmid=20024872}}</ref>

Revision as of 14:15, 14 July 2022

Hypertrophic scar
Hypertrophic scar (4 months after incident)
SpecialtyDermatology

A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids.[1] Like keloids, they form most often at the sites of pimples, body piercings, cuts and burns. They often contain nerves and blood vessels. They generally develop after thermal or traumatic injury that involves the deep layers of the dermis and express high levels of TGF-β.[citation needed]

Cause

Mechanical tension on a wound has been identified as a leading cause for hypertrophic scar formation.[3]

When a normal wound heals, the body produces new collagen fibers at a rate which balances the breakdown of old collagen. Hypertrophic scars are red and thick and may be itchy or painful. They do not extend beyond the boundary of the original wound, but may continue to thicken for up to six months. Hypertrophic scars usually improve over one or two years, but may cause distress due to their appearance or the intensity of the itching; they can also restrict movement if they are located close to a joint.[citation needed][dubious ]

Some people have an inherited tendency to hypertrophic scarring, for example, those with Ehlers–Danlos syndrome.

Prevention and treatment

It is not possible to completely prevent hypertrophic scars, so those with a history of them should inform their doctor or surgeon if they need surgery.

A 2021 systematic review brought together evidence from different studies that investigated using silicone gel sheeting to treat hypertrophic scars. The authors found 13 studies with a total of 468 participants that looked at this research question. A lot of different treatments were included but it was uncertain whether silicone gel sheets were more effective than most of these. Silicone gel sheets may improve the appearance of scars slightly compared with applying onion extract, and may reduce pain compared with no treatment with silicone gel sheets or pressure garments.[4]

Scar therapies, such as cryosurgery, may speed up the process of change from a hypertrophic scar to a flatter, paler one.[5]

Early hypertrophic scar should be treated with applied pressure and massage in the first 1.5–3 months. If necessary, silicone therapy should be applied later. Ongoing hypertrophy may be treated with corticosteroids injections.[6] Surgical revision may be considered after 1 year.[7]

See also

References

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ^ Jeschke, Marc G.; Kamolz, Lars-Peter; Sjöberg, Folke; Wolf, Steven E. (23 August 2012). Acute Burn Care. Handbook of Burns. Vol. 1. Springer Science & Business Media. ISBN 978-3-7091-0348-7.
  3. ^ Yagmur C, Akaishi S, Ogawa R, Guneren E (August 2010). "Mechanical receptor-related mechanisms in scar management: A review and hypothesis". Plastic and Reconstructive Surgery. 126 (2): 426–34. doi:10.1097/PRS.0b013e3181df715d. PMID 20375759. S2CID 23828914. cited in Acute Burn Care (2012) page 332.[2]
  4. ^ Jiang, Qingling; Chen, Junjie; Tian, Fan; Liu, Zhenmi (2021-09-26). Cochrane Wounds Group (ed.). "Silicone gel sheeting for treating hypertrophic scars". Cochrane Database of Systematic Reviews. 2021 (9). doi:10.1002/14651858.CD013357.pub2. PMC 8464654. PMID 34564840.{{cite journal}}: CS1 maint: PMC format (link)
  5. ^ Zouboulis, C. C.; Blume, U.; Büttner, P.; Orfanos, C. E. (September 1993). "Outcomes of cryosurgery in keloids and hypertrophic scars. A prospective consecutive trial of case series". Archives of Dermatology. 129 (9): 1146–1151. doi:10.1001/archderm.1993.01680300074011. ISSN 0003-987X. PMID 8363398.
  6. ^ Juckett, Gregory; Hartman-Adams, Holly (2009-08-01). "Management of keloids and hypertrophic scars". American Family Physician. 80 (3): 253–260. ISSN 1532-0650. PMID 19621835.
  7. ^ Cooper, Jason S.; Lee, Bernard T. (December 2009). "Treatment of facial scarring: lasers, filler, and nonoperative techniques". Facial Plastic Surgery. 25 (5): 311–315. doi:10.1055/s-0029-1243079. ISSN 1098-8793. PMID 20024872.