Symmetrical dimethylhydrazine

Symmetrical dimethylhydrazine
Names
	IUPAC name 1,2-Dimethylhydrazine
	Other names N,N'-Dimethylhydrazine; sym-Dimethylhydrazine; Hydrazomethane;
Identifiers
CAS Number	540-73-8 ;
3D model (JSmol)	Interactive image;
Abbreviations	SDMH
ChEBI	CHEBI:73755 ;
ChEMBL	ChEMBL162921 ;
ChemSpider	1282 ;
ECHA InfoCard	100.149.162
KEGG	C19176 ;
MeSH	1,2-Dimethylhydrazine
PubChem CID	1322;
UNII	IX068S9745 ;
CompTox Dashboard (EPA)	DTXSID0041228 ;
	InChI InChI=1S/C2H8N2/c1-3-4-2/h3-4H,1-2H3 Key: DIIIISSCIXVANO-UHFFFAOYSA-N ;
	SMILES CNNC;
Properties
Chemical formula	C2H8N2
Molar mass	60.100 g·mol−1
Appearance	Colourless liquid
Odor	Ichtyal, ammoniacal
Density	827.4 kg m−3 (at 20 °C)
Melting point	−9 °C (16 °F; 264 K)
Boiling point	87 °C; 188 °F; 360 K
Solubility in water	Miscible
Thermochemistry
Heat capacity (C)	171.04 J K−1 mol−1
Std molar; entropy (S⦵298)	199.15 J K−1 mol−1
Std enthalpy of; combustion (ΔcH⦵298)	−1.9872–−1.9788 kJ mol−1
Related compounds
Related compounds	Biurea; Daminozide;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

1,2-Dimethylhydrazine, or symmetrical dimethylhydrazine, is one of the two isomers of dimethylhydrazine. It is a potent carcinogen that acts as a DNA methylating agent. It is used to induce colon tumors in experimental animals.^[2]^[4]^[5]

References

^ ^a ^b ^c ^d 74-79-3 1,2-Dimethylhydrazine
^ ^a ^b 1,2-Dimethylhydrazine from PubChem
^ Record of 1,2-Dimethylhydrazin in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 21 March 2008.
^ Cruse, J. P.; Lewin, M. R.; Ferulano, G. P.; Clark, C. G. (1978). "Co-carcinogenic effects of dietary cholesterol in experimental colon cancer". Nature. 276 (5690): 822–5. doi:10.1038/276822a0. PMID 723955.
^ Wijnands, M.V.W. (1999). "A comparison of the effects of dietary cellulose and fermentable galacto-oligosaccharide, in a rat model of colorectal carcinogenesis: fermentable fibre confers greater protection than non-fermentable fibre in both high and low fat backgrounds". Carcinogenesis. 20 (4): 651–6. doi:10.1093/carcin/20.4.651. PMID 10223195.

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[CAS-1] 74-79-3 1,2-Dimethylhydrazine

[PubChem_Compound-2] 1,2-Dimethylhydrazine from PubChem

[3] Record of 1,2-Dimethylhydrazin in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 21 March 2008.

[4] Cruse, J. P.; Lewin, M. R.; Ferulano, G. P.; Clark, C. G. (1978). "Co-carcinogenic effects of dietary cholesterol in experimental colon cancer". Nature. 276 (5690): 822–5. doi:10.1038/276822a0. PMID 723955.

[5] Wijnands, M.V.W. (1999). "A comparison of the effects of dietary cellulose and fermentable galacto-oligosaccharide, in a rat model of colorectal carcinogenesis: fermentable fibre confers greater protection than non-fermentable fibre in both high and low fat backgrounds". Carcinogenesis. 20 (4): 651–6. doi:10.1093/carcin/20.4.651. PMID 10223195.

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See also

References