The 2012 Comerica Bank Challenger was a professional tennis tournament played on hard courts. It was the 24th edition of the tournament which was part of the 2012 ATP Challenger Tour. It took place in Aptos, United States between 6 and 12 August July 2012.
Singles main draw entrants
- 1 Rankings are as of July 30, 2012.
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw: