This album was well-received by critics. The Times gave it 8/10 and wrote: "Siouxsie, has rarely been in better voice. The opening track, "2nd Floor" is a fantastically knowing melodrama, riding a techno pulse, while the ominous, epic Exterminating Angel pursues its prey in lamplit streets. It's entrancing, hypnotic and inventive".The Sunday Times also praised and presented it in these glowing terms: "Siouxsie's voice has lost none of its ability to seduce and unsettle. The sound is percussive, defined by Budgie's supple rhythm work. Exterminating Angel is exquisitely menacing, while the sinuous Another Planet grows to a shuddering climax."Uncut gave the album 4/5 and Chris Roberts said: "Sioux's always been at her best as a harsh declaimer, PJ Harvey on steroids, but there are phases where she whispers, breathes, reaches for vulnerability", before concluding "The Creatures have jettisoned comfort and are phoning home from a new end zone. Anima Animus crackles."
The original title of the album was Gifthorse, then Mount Venus, before the duo changed their minds to finally opt for Anima Animus. The first single "Second Floor" was issued in late 1998, shortly after the four-track EP, "Eraser Cut". Another single, "Say", featured two unreleased B-sides, the acoustic "Broken" and the atmospheric "All She Could Ask For". The latter song opened their 1999 concerts. All of this material was later included on the U.S. Retrace compilation.