Bis(2-ethylhexyl) adipate

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Bis(2-ethylhexyl) adipate
Abbreviations DEHA
CAS number 103-23-1 YesY
PubChem 7641
ChemSpider 7358 YesY
KEGG C14240 YesY
Jmol-3D images Image 1
Molecular formula C22H42O4
Molar mass 370.57 g mol−1
Appearance colourless oily liquid
Density 0.93 g/cm3
Melting point −67.8 °C (−90.0 °F; 205.3 K)
Boiling point 417 °C (783 °F; 690 K)
Solubility in water negligible
Vapor pressure 2.6 mm Hg at 200 °C
MSDS Oxford University
EU classification Irritant Xi
Flash point 196 °C (385 °F; 469 K)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY (verify) (what is: YesY/N?)
Infobox references

Bis(2-ethylhexyl) adipate or DEHA is a plasticizer. DEHA is an ester of 2-ethylhexanol and adipic acid. Its chemical formula is C22H42O4.

DEHA is sometimes called "dioctyl adipate", incorrectly. Other names include diisooctyl adipate and di(2-ethylhexyl) adipate.


DEHA is used as a functional hydraulic fluid, and a component of aircraft lubricants. It is sometimes also used as an ingredient in PVC-based plastic wrap.


DEHA has been demonstrated to induce liver adenomas and carcinomas in mice but not in rats. According to the International Agency for Research on Cancer (IARC), it is "not classifiable as to its carcinogenicity to humans (Group 3),"[1] suggesting inadequate evidence of human carcinogenicity.[2] While once on a U.S. Environmental Protection Agency list of toxic chemicals under the Emergency Planning and Community Right-to-Know Act, it has been removed because it "cannot be reasonably anticipated to cause [...] irreversible chronic health effects."[3]


  1. ^ IARC - Summaries & Evaluations: DI(2-ETHYLHEXYL) ADIPATE 77, 2000, p. 149, retrieved 2008-12-20 
  2. ^ Inchem Preamble Evaluation, 1-5-1999, retrieved 2008-12-20  Check date values in: |date= (help)
  3. ^ Bottle Royale, retrieved 2008-12-20