Corneal limbus
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| Corneal limbus | |
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| Schematic diagram of the human eye. | |
| Latin | limbus corneae |
The corneal limbus is the border of the cornea and the sclera (the white of the eye). The limbus is a common site for the occurrence of corneal epithelial neoplasm. The Limbus contains radially oriented fibrovascular ridges known as the palisades of Vogt that may harbour a stem cell population.[1] The palisades of Vogt are more common in the superior and inferior quadrants around the eye.[2] Aniridia, a developmental anomaly of the iris, disrupts the normal barrier of the cornea to the conjunctival epithelial cells at the limbus.
[edit] References
- ^ Thomas PB, Liu YH, Zhuang FF, Selvam S, Song SW, Smith RE, Trousdale MD, Yiu SC (2007). "Identification of Notch-1 expression in the limbal basal epithelium". Mol. Vis. 13: 337–44. PMC 2633467. PMID 17392684. http://www.molvis.org/molvis/v13/a37/.
- ^ Goldberg MF, Bron AJ (1982). "Limbal palisades of Vogt". Trans Am Ophthalmol Soc 80: 155–71. PMC 1312261. PMID 7182957. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1312261.
[edit] External links
- Atlas of anatomy at UMich eye_1 - "Sagittal Section Through the Eyeball"
- http://www.vetmed.ucdavis.edu/courses/vet_eyes/images/s_4021_2.jpg
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