Corydalis ambigua
| Corydalis ambigua | |
|---|---|
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| Scientific classification | |
| Kingdom: | Plantae |
| Division: | Magnoliophyta |
| Class: | Magnoliopsida |
| Order: | Ranunculales |
| Family: | Papaveraceae |
| Genus: | Corydalis |
| Species: | C. ambigua |
| Binomial name | |
| Corydalis ambigua Cham. & Schltdl.[1] |
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Corydalis ambigua is a tuberous early flowering east Asian flowering plant species. Its exact native range is obscure due to taxonomic confusion.[1] It is one of the sources of the drug tetrahydropalmatine.
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[edit] Traditional Chinese medicine
A related species, C. yanhusuo is one of the 50 fundamental herbs used in traditional Chinese medicine. (C. remota is also substituted.[citation needed]) In Chinese it is called yán hú suǒ (Chinese: 延胡索).[clarification needed]
[edit] Chemistry
Corydalis ambigua contains a variety of alkaloids including corynoline, acetylcorynoline d-corydalin, dl-tetrahydropalmatine, protopine, tetrahydrocoptisine, dl-tetrahydrocoptisine, d-corybulbine and allo-crytopine.[2][3][4][5]
Chemical derivatives of tetrahydroprotoberberines present in Corydalis ambigua have been studied as potential ways to increase pain tolerance and for treating drug addiction.[6] Further, they may represent a category of neurotransmitter stabilizers which have potential use in broad range of psychotic and neurological disorders.[6]
[edit] See also
[edit] References
- ^ a b "Corydalis ambigua information from NPGS/GRIN". USDA. 28-Nov-2001. http://www.ars-grin.gov/cgi-bin/npgs/html/taxon.pl?403065. Retrieved 2008-02-04.
- ^ Zhu, Da-Yuan et al. (1981). "IDENTIFICATION OF THE STRUCTURES OF CORYDALIS F, I, J AND K". Acta Chimica Sinica. http://en.cnki.com.cn/Article_en/CJFDTOTAL-HXXB198103013.htm.
- ^ Ma, W.g.; Fukushi, Y.; Tahara, S. (1999). "Fungitoxic alkaloids from Hokkaido Corydalis species". Fitoterapia 70 (3): 258–265. doi:10.1016/S0367-326X(99)00045-3. http://www.sciencedirect.com/science/article/pii/S0367326X99000453.
- ^ Hiraoka, Noboru et al. (2004). "Alkaloid production by somatic embryo cultures of Corydalis ambigua". Plant Biotechnology 21 (5): 361–366. doi:10.5511/plantbiotechnology.21.361. http://docs.google.com/viewer?a=v&q=cache:-ek1ckxlMJIJ:www.wdc-jp.biz/pdf_store/jspcmb/pdf/pb21_5/21_361.pdf+Corydalis+ambigua+garden+plant&hl=en&pid=bl&srcid=ADGEESi1WgJhdhxL7S9cmE7yDF_PZgmwZSUb_uy8CZD86BwGU1vI9z7LzEzf-mCgQTYhcVYbN0KTMRsF5XZYD6NTv4FyWq8rV-B9TjYUMinNj_X8Ji0XqYZkL4f4TGsqOb-aWTMfw3Il&sig=AHIEtbSyGXyQIL8TlEo5XXC_s1i3ve0UUQ.
- ^ Zhu, Xing-Zu (1991). "Memórias do Instituto Oswaldo Cruz - Development of natural products as drugs acting on central nervous system". Memórias do Instituto Oswaldo Cruz 86: 173. doi:10.1590/S0074-02761991000600039.
- ^ a b Zhen X.-C. (2010). "Tetrahydroprotoberberines (THPBs) in neuropsychological disorders: Recent development and prospective (Abstract S-33.004)". International Journal of Neuropsychopharmacology 13 (SUPPL. 1): 41.
[edit] Further reading
- Bhakuni, D. S.; Chaturvedi, Rekha (1983). "The Alkaloids of Corydalis meifolia". Journal of Natural Products 46 (4): 466–70. doi:10.1021/np50028a006. PMID 6631434.
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