DKK3

DKK3
Identifiers
Aliases	DKK3, REIC, RIG, dickkopf WNT signaling pathway inhibitor 3, CRRL
External IDs	OMIM: 605416 MGI: 1354952 HomoloGene: 8303 GeneCards: DKK3
Gene location (Human)
Chr.	Chromosome 11 (human)
End	12,009,769 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	111,758,264 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; middle temporal gyrus; ; external globus pallidus; ; entorhinal cortex; ; vena cava; ; stromal cell of endometrium; ; pons; ; Region I of hippocampus proper; ; internal globus pallidus;
	Top expressed in
	ciliary body; ; iris; ; aortic valve; ; calvaria; ; ascending aorta; ; utricle; ; primary motor cortex; ; atrioventricular valve; ; superior frontal gyrus; ; corneal stroma;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	co-receptor binding; receptor antagonist activity;
Cellular component	extracellular region; extracellular space;
Biological process	negative regulation of anti-Mullerian hormone signaling pathway; multicellular organism development; negative regulation of cortisol biosynthetic process; negative regulation of Wnt signaling pathway; anatomical structure morphogenesis; negative regulation of transcription, DNA-templated; Wnt signaling pathway; adrenal gland development; negative regulation of canonical Wnt signaling pathway; regulation of transforming growth factor beta receptor signaling pathway; negative regulation of aldosterone biosynthetic process; extracellular negative regulation of signal transduction; negative regulation of signaling receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	27122
	50781
	ENSG00000050165
	ENSMUSG00000030772
	Q9UBP4
	Q9QUN9
	NM_001018057; NM_013253; NM_015881; NM_001330220
	NM_015814; NM_001360257; NM_001360260; NM_001360261
	NP_001018067; NP_001317149; NP_037385; NP_056965
	NP_056629; NP_001347186; NP_001347189; NP_001347190
	Wikidata
View/Edit Human	View/Edit Mouse

Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000050165 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030772 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA (Dec 1999). "Functional and structural diversity of the human Dickkopf gene family". Gene. 238 (2): 301–13. doi:10.1016/S0378-1119(99)00365-0. PMID 10570958.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

References

Further reading