|This article relies largely or entirely upon a single source. (August 2014)|
The name has many spellings, which include Frangipane, Freiapane, Fricapane and Fresapane.
The family played a significant part in the struggle between Pope Gregory VII and Holy Roman Emperor Henry IV, and briefly governed Rome from 1107–1108. In the feud between the Orsini and Colonna families they supported the Orsini. Their power was at its greatest when they achieved the election of Pope Honorius II in 1124. In his Trattatello in laude di Dante, Boccaccio traces the descent of Dante from the family.
In 1268 Giovanni Frangipane, lord of Astura, betrayed the boy Conradin, Duke of Swabia, who took refuge with him after his defeat at the Battle of Tagliacozzo. Frangipane arrested him and handed him over to Charles of Anjou, who beheaded him.
- Cencio I Frangipane
- Cencio II Frangipane
- Oddone Frangipane
- Saint Ottone Frangipane is also believed have been a member of this family.