It was situated above and had its entrance within the St. Christopher’s Inn pub, situated on the east side of the forecourt of Greenwich station.
In December 1995, the Galleon Theatre Company became the resident company at the theatre (at that time named the Prince Theatre). Galleon was a touring company founded in 1988 by Alice de Sousa and Bruce Jamieson. In September 1998, the theatre closed, but was revived after a campaign to save it and re-opened with new facilities on 30 May 2000.
In January 2012 the Greenwich Playhouse's closure as a producing theatre was again announced, coming into effect in April 2012.