Integrated DNA Technologies
|Founded||Coralville, IA, USA 1987|
|Founders||Dr. Joseph A. Walder|
|Headquarters||Coralville, IA, U.S.|
|Number of locations||Coralville, IA USA - San Diego, CA USA - Skokie, IL USA - Leuven, Belgium - Singapore|
|Area served||Research and diagnostics life sciences market|
Integrated DNA Technologies, Inc. (IDT), headquartered in Coralville, Iowa, is the world's largest supplier of custom nucleic acids, serving the areas of academic research, biotechnology, clinical diagnostics, and pharmaceutical development. IDT's primary business is the manufacturing of custom DNA and RNA oligonucleotides (oligos) for research applications.
Joseph Walder, M.D., Ph.D. (Northwestern University), founded Integrated DNA Technologies, Inc. in 1987 through a partnership with Baxter Healthcare Corporation at the University of Iowa Technology Innovation Center business incubator. In its first 10 years, IDT grew from a startup with 10 synthesizing machines to a small company with more than 500, shipping an average 44,000 custom oligos per day to more than 82,000 customers worldwide. IDT products are enabling scientists to test for genetic diseases, discover new drugs, and develop new treatment models tailored to the specific needs of individual patients.
IDT's mission is to enable discovery in biology and medicine. The company strives to achieve this by improving nucleic acid synthesis technology and developing new applications for the use of DNA- and RNA-based compounds. IDT's advanced synthesis group combines expertise in chemistry, molecular biology, and engineering to produce and purify complex nucleic acids of all kinds.
Synthetic oligonucleotides are used in various molecular biology applications, e.g., polymerase chain reaction (PCR), molecular beacons, microarrays, mutagenesis, RNAi, antisense and de novo gene construction. Published bioinformatics algorithms can predict biophysical properties of oligonucleotides from their sequence and estimate oligonucleotide performance in specific assays, when used singly or together with other sequences. IDT's SciTools is a free online suite of computational software tools that enable molecular biologists to design, evaluate and make informed decisions about the properties of nucleic acid sequences. Instructions and help to each software tool can be found at the top of web input forms. The code is regularly updated when more accurate models and algorithms are published.
|Custom Oligonucleotide Synthesis & Purification||Oligonucleotide Modifications|
|cGMP Manufacturing||Gene Expression Assays|
|Gene Silencing Products||Molecular Biology Reagents|
|Fluorescence-Based Applications||ReadyMade Primers and Products|
|Synthetic Biology||Next Generation Sequencing Products|
IDT is a member of the Technology Association of Iowa.
- Owczarzy R, Tataurov AV, Wu Y, et al. (July 2008). "IDT SciTools: a suite for analysis and design of nucleic acid oligomers". Nucleic Acids Res. 36 (Web Server issue): W163–9. doi:10.1093/nar/gkn198. PMC 2447751. PMID 18440976.