Integrated DNA Technologies
|Founded||Coralville, IA, USA 1987|
|Founder(s)||Dr. Joseph A. Walder|
|Headquarters||Coralville, IA, U.S.|
|Number of locations||Coralville, IA USA - San Diego, CA USA - Skokie, IL USA - Leuven, Belgium|
|Area served||Research and diagnostic life science market|
Integrated DNA Technologies, Inc. (IDT), headquartered in Coralville, Iowa, is the largest supplier of custom nucleic acids in the U.S., serving the areas of academic research, biotechnology, clinical diagnostics, and pharmaceutical development. IDT's primary business is the manufacturing of custom DNA and RNA oligonucleotides (oligos) for research applications.
Joseph Walder, M.D., Ph.D. (Northwestern University), founded Integrated DNA Technologies, Inc. in 1987 through a partnership with Baxter Healthcare Corporation at the University of Iowa Technology Innovation Center business incubator. In its first 10 years, the company grew from a start-up with 10 synthesizing machines to one with more than 500, shipping an average 36,000 custom oligos per day to its over 77,000 customers worldwide, enabling them to test for genetic diseases, discover new drugs, and develop new treatment models tailored to the specific needs of individual patients.
IDT's primary mission is to improve nucleic acid synthesis technology and develop new applications for the use of DNA and RNA-based compounds. IDT's advanced synthesis group combines expertise in chemistry, molecular biology and engineering to produce and purify complex nucleic acids of all kinds.
Synthetic oligonucleotides are widely employed in various molecular biology applications, e.g. polymerase chain reaction (PCR), molecular beacons, microarrays, mutagenesis, RNAi, antisense and de novo gene construction. Published bioinformatics algorithms can predict biophysical properties of oligonucleotides from their sequence and estimate performance of oligonucleotides in specific assays both singly and together with other sequences. IDT's SciTools is a free online suite of computational software tools that enable molecular biologists to design, evaluate and make informed decisions about the properties of nucleic acid sequences. Instructions and help to each software tool can be found at the top of web input forms. The code is regularly updated when more accurate models and algorithms are published.
|Custom Oligonucleotide Synthesis & Purification||Oligonucleotide Modifications|
|cGMP Manufacturing||Gene Expression Assays|
|Gene Silencing Products||Molecular Biology Reagents|
|Fluorescence-Based Applications||ReadyMade Primers and Products|
|Synthetic Biology||Next-Generation Sequencing Products|
IDT is a member of the Technology Association of Iowa.
- Owczarzy R, Tataurov AV, Wu Y, et al. (July 2008). "IDT SciTools: a suite for analysis and design of nucleic acid oligomers". Nucleic Acids Res. 36 (Web Server issue): W163–9. doi:10.1093/nar/gkn198. PMC 2447751. PMID 18440976.