October 11, 1984
Charlottetown, Prince Edward Island, Canada
|Residence||Los Angeles, California, United States|
|Spouse(s)||Torre Catalano 2010–present|
Life and career
MacIsaac was born and raised in Charlottetown, Prince Edward Island, the youngest of three girls, her mother Irene was one of twelve. She started her career playing Emily Byrd Starr in the Emily of New Moon television series, based on the books by Lucy Maud Montgomery.
She has appeared in several plays including the 2006 play The Wild Duck in which she played Hedwig and was nominated for a Dora Mavor Moore Award Award for "Outstanding Performance by a Female in a Principal Role - Play". In 2008, she played Paige in a Wes Craven play Last House on the Left. She also performed in three consecutive productions of Soulpepper Theatre Company's Our Town as Emily, beginning in 2006.
In a 2007 Entertainment Weekly article, she stated she has been inspired by Julia Roberts from the age of four and was self-described as "obsessed". She also stated she would like to perform alongside her in a film, particularly "a female version of Twins".
In late 2012 MacIsaac began a main role on the NBC comedy 1600 Penn as the president's eldest daughter, Becca. Brittany Snow was originally cast as Becca but because she did not physically resemble and fit in well with the other family members, Martha MacIsaac was cast. In a 2012 interview with the CBC Radio series Island Morning, she revealed that 1600 Penn was her last audition before she considered returning to Canada.
1600 Penn's cancellation was announced on the 9th of May 2013. 
|2003||This Time Around||Young Gabby Castellani||Film Debut|
|2004||Suburban Madness||Vivian Leigh Bacha|
|2005||Ice Princess||Mean Party Girl|
|2005||I Do, They Don't||Moira Lewellyn|
|2006||Night of Terror||Olivia Dunne|
|2007||In God's Country||Charlotte|
|2009||Last House on the Left, TheThe Last House on the Left||Paige|
|2009||Thaw, TheThe Thaw||Evelyn|
|2010||Faith, Fraud & Minimum Wage||Casey McCullen|
|2012||For a Good Time, Call...||Inmate|
|2012||Dead Before Dawn||Charlotte Baker|
|1998–2000||Emily of New Moon||Emily Byrd Starr|
|2006||This Is Wonderland||Kristy Hausman|
|2006–2008||Di-Gata Defenders||Melosa (voice)||52 episodes|
|2007–2008||Magi-Nation||Edyn (voice)||26 episodes|
|2008||Friends and Heroes||Sarah (voice)||13 episodes|
|2010–2011||Greek||Dana Stockwell||9 episodes|
|2011||Marcy||Martha||Episode: "Marcy Does an Acting Class"
Episode: "Marcy Does a Pool Party"
|2012||Spyburbia||Cissy (voice)||Episode: "Pilot"|
|2012||Family Guy||? (voice)||Episode: "Friends Without Benefits"|
|2012–2013||1600 Penn||Becca Gilchrist|
- "From New Moon to Superbad: P.E.I.'s MacIsaac goes Hollywood". cbc.ca. 2007-01-08. Retrieved 2013-02-11.
- Rainnie, Matt (2012-11-18). "Martha MacIsaac - 1600 Penn". cbc.ca. Retrieved 2013-02-11.
- Ouzounian, Richard (2005-07-22). "Ibsen's secrets told exceedingly well". Toronto Star. Retrieved 2013-02-11.
- Jones, Kenneth (2006-06-06). "Precious Stuff: Lord of the Rings Is Lord of Toronto's Dora Nominees, With 15 Nods". playbill.com. Retrieved 2013-02-11.
- Garrett, Diane (2008-02-08). "Dillahunt joins cast of 'Last House'". variety.com. Retrieved 2013-02-11.
- Cole, Sally (2013-01-09). "Martha MacIsaac visits White House". theguardian.pe.ca. Retrieved 2013-02-11.
- Coulbourn, John (2006-02-03). "Soulpepper builds a beautiful 'Our Town'". jam.canoe.ca. Retrieved 2013-02-11.
- Bell, Carrie (2007-08-31). "Martha MacIsaac is dying to work with...". ew.com. Retrieved 2013-02-11.
- Andreeva, Nellie (2012-04-04). "NBC Pilot ’1600 Penn’ Recasts A Role". deadline.com. Retrieved 2013-02-11.
- "Martha MacIsaac Makes "Minimum Wage"". seaandbescene.com. 2010-09-15. Retrieved 2013-02-11.