The medial epicondyle of the humerus in humans is larger and more prominent than the lateral epicondyle and is directed slightly more posteriorly in the anatomical position. In birds, where the arm is somewhat rotated compared to other tetrapods, it is called ventral epicondyle of the humerus. In comparative anatomy, the more neutral term entepicondyle is used.
The ulnar nerve runs in a groove on the back of this epicondyle.The medial epicondyle protects the ulnar nerve. The ulnar nerve is vulnerable because it passes close to the surface along the back of the bone. Striking the medial epicondyle causes a tingling sensation in the ulnar nerve. This response is known as striking the “funny bone”. The name funny bone could be from a play on the words humorous and humerus, the bone on which the medial epicondyle is located. The medial epicondyle is located on the distal end of the humerus. Additionally, the medial epicondyle is inferior to the medial supracondylar ridge. It is also proximal to the olecranon fossa.