N,N-Dimethylethylamine

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N,N-Dimethylethylamine
N,N-Dimethylethylamine.svg
Identifiers
CAS number 598-56-1 YesY
PubChem 11723
ChemSpider 11230 YesY
Jmol-3D images Image 1
Properties
Molecular formula C4H11N
Molar mass 73.14 g mol−1
Appearance Volatile liquid at room temp.
Density 0.7±0.1 g/cm3
Melting point −140 °C (−220 °F; 133 K)
Boiling point 36.5 °C (97.7 °F; 309.6 K)
Vapor pressure 495.4±0.1 mmHg
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

N,N-Dimethylethylamine (DMEA), sometimes referred to as dimethylethylamine, is an organic compound with formula C4H11N. It is an industrual chemical that is mainly used in foundries as a catalyst for sand core production.[1] Dimethylethylamine is a malodorous, volatile liquid at room temperature that is excreted at greater concentrations with larger dietary intake of trimethylamine.[2] It has recently been identified as an agonist of human trace amine-associated receptor 5.[3]

See also[edit]

 • Odorant  • Olfactory receptor
 • Trace amine  • Trace amine-associated receptor

References[edit]

  1. ^ "Dimethylethylamine". BASF The Chemical Company. Retrieved 4 May 2014. 
  2. ^ "N,N-Dimethylethylamine". Toxnet. Hazardous Substance Data Bank. Retrieved 4 May 2014. The aim was to study the effect of trimethylamine (TMA) on the metabolism of the industrial catalyst N,N-dimethylethylamine to ascertain whether biological monitoring of industrial exposure to N,N-dimethylethylamine is compromised and excretion of the malodorous N,N-dimethylethylamine in sweat and urine is increased by dietary intake of TMA....Although the increased urinary and hidrotic excretion of N,N-dimethylethylamine may contribute to body odor problems, they were primarily due to TMA excretion, which is much the greater. 
  3. ^ Wallrabenstein I, Kuklan J, Weber L, Zborala S, Werner M, Altmüller J, Becker C, Schmidt A, Hatt H, Hummel T, Gisselmann G (2013). "Human trace amine-associated receptor TAAR5 can be activated by trimethylamine". PLoS ONE 8 (2): e54950. doi:10.1371/journal.pone.0054950. PMC 3564852. PMID 23393561.