TAAR2

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Trace amine associated receptor 2
Identifiers
Symbols TAAR2 ; GPR58
External IDs OMIM604849 MGI2685071 HomoloGene110760 IUPHAR: TAAR2 GeneCards: TAAR2 Gene
RNA expression pattern
PBB GE TAAR2 221394 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9287 209512
Ensembl ENSG00000146378 ENSMUSG00000059763
UniProt Q9P1P5 Q5QD17
RefSeq (mRNA) NM_001033080 NM_001007266
RefSeq (protein) NP_001028252 NP_001007267
Location (UCSC) Chr 6:
132.94 – 132.95 Mb
Chr 10:
23.94 – 23.94 Mb
PubMed search [1] [2]

Trace amine-associated receptor 2 is a protein that in humans is encoded by the TAAR2 gene.[1][2][3]

A recent paper showed that, along with TAAR1, TAAR2 is required for full activity of trace amines in PMN cells.[4]


See also[edit]

References[edit]

  1. ^ Lee DK, Lynch KR, Nguyen T, Im DS, Cheng R, Saldivia VR, Liu Y, Liu IS, Heng HH, Seeman P, George SR, O'Dowd BF, Marchese A (Jun 2000). "Cloning and characterization of additional members of the G protein-coupled receptor family". Biochim Biophys Acta 1490 (3): 311–23. doi:10.1016/s0167-4781(99)00241-9. PMID 10684976. 
  2. ^ Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC (Feb 2005). "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors". Genomics 85 (3): 372–85. doi:10.1016/j.ygeno.2004.11.010. PMID 15718104. 
  3. ^ "Entrez Gene: TAAR2 trace amine associated receptor 2". 
  4. ^ Babusyte A, Kotthoff M, Fiedler J, Krautwurst D (March 2013). "Biogenic amines activate blood leukocytes via trace amine-associated receptors TAAR1 and TAAR2". J. Leukoc. Biol. 93 (3): 387–94. doi:10.1189/jlb.0912433. PMID 23315425. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.