Paolo Zamboni (b. 25 March 1957 in Ferrara, Italy) is an Italian doctor and vascular surgeon who found in a preliminary study that in over 90% of the participants afflicted with multiple sclerosis there were several problems in veins draining their brain, like stenosis or defective valves. He noticed high level of accumulation of iron deposits in the brain, due to restricted outflow of blood.
The theory is controversial, but the Multiple Sclerosis Society of Canada accepted Zamboni's treatment as promising. A University of Buffalo research team is also developing a program to test Zamboni's theory. Since 2010, there has been more research that disputes the Zamboni theory.
- Singh AV, Zamboni P (December 2009). "Anomalous venous blood flow and iron deposition in multiple sclerosis". J. Cereb. Blood Flow Metab. 29 (12): 1867–78. doi:10.1038/jcbfm.2009.180. PMID 19724286.
- Picard, André; Favaro, Avis (2009-11-20). "Researcher's labour of love leads to MS breakthrough". The Globe and Mail (Toronto).
- "The Liberation Treatment: A whole new approach to MS" (FLV, Web page). CTV Television Network, W5. 2009. Retrieved 2009-12-10.
- Roberts, Michelle (2009-11-27). "MS 'blood blockage theory' tested". BBC News. Retrieved 2010-05-21.
- "Massive study disputes Zamboni theory of multiple sclerosis". The Globe and Mail. 2011-08-10.
- Brief CV Paolo Zamboni, MD on Hilarescere Foundation
- Paolo Zamboni research profile on BiomedExperts
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