Pydna was already a part of the Macedonian kingdom under Alexander I (Thucydides I.131.1). It was unsuccessfully besieged by the Athenians in 432 BC and again, after seceding from the Macedonian kingdom, in 410 BC by Archelaus I who successfully captured the city and transferred its population further inland, possibly at the site of modern Kitros; however, the old site was re-peopled in the early 4th century. The Athenians, under Timotheus, seized Pydna in 364-363 BC, only to have it retaken in 357 BC by Philip II of Macedon. Pydna would remain part of the kingdom of Macedonia until its Roman conquest. In 317 BC, Alexander III's mother, Olympias took refuge there to escape from Cassander's wrath, incurred by Olympias' scheming against Phillip III and his wife. Cassander besieged the city and managed to capture it during the spring of 316 BC.