The anthology is presented as a series of stories told by an ancient vampire to a group of young Watchers. Tales of the Vampires is the tale of that storytelling session and functions as a bridge among the other items in the anthology. The stories in this series are generally considered to be an official part of the Buffyverse canon.
Drusilla has been captured by a human inquisitor and thrown into a Prague jail. The inquisitor proceeds to torture Drusilla in a unique chair built for that purpose in 1478. He hopes Dru will remember the pain forever, serving as a warning to other vampires to stay away from the people of Prague.
Drusilla tries to recount the things that make her happy, including little girls lost at the fair and little boys wandering too far from home, so that she can forget the torture. Spike is lying imprinted into the ground under the bridge he was thrown from by a Prague mob that shoved a stake into his chest, inches from his heart, not dusting him so that he can flee and warn other vampires to stay away from Prague. He then moves across the city, finds Drusilla, and dispatches her captor.
Spike picks up a damaged Drusilla and carries her out the door, headed for a first showdown with a Slayer in a town with a Hellmouth called Sunnydale.
A young teenage vampire named Stacy explains how, while human, she was enchanted by the idea of magic. Stacy's tale starts with her explaining that she is different and special because she understands magic. As she tries to explain this to her two friends, Jason and Dwayne, during a Lord of the Rings showing that captivates her, we learn that she remains isolated in her beliefs.
After the movie, in her vision of magic she is an elf princess, battling orcs. In reality, she spends time battling her friend Jason's unwanted advances. Stacy again reminds us that most people think her magic is silly, but then surprises us by stating that most people have never been murdered either. We are then taken through Stacy's siring at a party from which she rises up after two days in the bushes. No one found her in all that time.
This young girl then becomes connected—"evil, but connected" She finally realizes that the magic lies not with the solitary elves, but with the orc hordes, the monsters. She claims her magic with a band of other vampires.
Spot the Vampire is a poem punctuated. The artwork is influenced by 1950s style children's magazine games and New Yorker magazines. The story is simply a single frame from a 1950s-looking department store on Christmas shopping day. The reader is then invited to look at each person in the frame to discover which is the vampire.
Buffy, Kira, and another scythe-activated Slayer break into the stronghold of the legendary vampire, Vlad Dracula, in an effort to rescue Buffy's comrade, Xander who had been placed in a trance to serve as Dracula's manservant. After a brief battle, Dracula finally reluctantly agrees to release Xander from the trance and return him to Buffy. This story marks the first appearance of Buffy and Xander following Chosen, the final episode of the television series.
A vampire from the 15th century who was formerly an inquisitor has become maddened over the centuries and believes that the clergy should be killed because they are too 'certain' that God exists and that God prefers doubt. He thinks that he is an agent of God - until one night when he is buying candy at a gas station in San Gabriel. A confrontation of minds ensues between the vampire and a dog-collared man who claims to be God.