Talk:Asplenia

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Merge proposal[edit]

I suggest merging Congenital asplenia into the Asplenia article. Congenital is but one of many causes for asplenia, but the consequences are the same irrescpective if due to congenital absence, subsequent surgical splenectomy or auto-splenectomy due to infarction of the spleen due to conditions such as sickle cell disease. The asplenia article could perhaps have its lead-in split with a "Classification" section (see WP:MEDMOS guideline) for the causes (and this would also be a better place to put current mention of hyposplenia). David Ruben Talk 17:05, 7 August 2007 (UTC)

No comments for a week - merged and split lead-in as above David Ruben Talk 00:28, 14 August 2007 (UTC)

Suggestion[edit]

I would like to make one observation which might lead to a qualified person editing this article. Where the spleen is removed surgically, the surgeon will sometimes leave a bit of spleen in there, and in some subjects this can grow to become a functional or partially functional spleen over time. Such patients may be less likely to be at risk than those who are completely asplenic, and perhaps would not need long term prophylaxis. Sorry I have no references and no time to find them so... over to you..—Preceding unsigned comment added by 82.33.82.91 (talkcontribs) (18:11, 4 January 2008

Thank you, yes a partial splenectomy will leave residual splenic function and so greatly (?totally) eliminate asplenic risks discussed. Of course there will a difference between planed proceedures in say hereditory spherocytosis treatement where a small amount of "healthy spleen" is left untouched and hence good postoperative splenic phagocytic function may be predicted, as against splenectomy after trauma where a small part of an otherwise damaged spleen is put back in place in teh hope that it may "take", but theer is less certainty for this. I'll seek out some sources (but non-surgical lay opinion is that in the latter case asplenia measure would probably at least need be instituted in the short-term until the auto-transplanted splenic section can become fully functional - but lets see what literature (or a surgeon/haematologist) might advise us) David Ruben Talk 20:48, 4 January 2008 (UTC)

NEJM review[edit]

doi:10.1056/NEJMcp1314291 JFW | T@lk 13:27, 24 July 2014 (UTC)