Talk:Drug delivery

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[edit] Proposed Merge

It seems to me that Drug delivery and Route of administration are on the same topic. I suggest that these articles should be merged with appropriate redirects.-- aBSuRDiST -^T J ^C- 23:47, 21 July 2007 (UTC)

I do not think it is correct to merge the two articles. Drug delivery is completely different to Route of administration. Drug delivery refers to various carriers used to make the current treatment modalities more effective and the other one is various routes available for drug administration. —The preceding unsigned comment was added by 76.195.209.11 (talk) 05:20, August 21, 2007 (UTC)

I would not merge the articles. Drug delivery usually refers to the technologies which enable administration of drug compounds through various routes. It also refers to different methods of administration within the same route (injection - depot, IV, IP, bolus, infusion...) When preferred routes do not provide the desired efficacy or toxicity, then drug delivery technologies may be employed. 68windmills 23:46, 14 September 2007 (UTC)

As it looks right now i would definitely merge the articles - but in general drug administration is different from drug delivery. Drug administration routes include intravenous, oral, rectal, sublingual, buccal, pulmonal, subcutaneous, vaginal, topical and others. Basically, these are different strategies for getting the active compound into the bloodstream or lymph system. Drug delivery on the other hand covers technologies to enhance the specific accumulation of active compound at the site of disease. Drug delivery systems alter the pharmacokinetics and biodistribution of a drug and thus increase its effect. They can protect the drug from degradation (e.g. conjugation), protect the patient from adverse effects (e.g. sustained release), passively increase the amount of drug at the site of disease (e.g liposomes in tumors) or actively target drugs to certain tissues (e.g. antibody-conjugates). —Preceding unsigned comment added by 85.81.181.65 (talk) 20:05, 11 November 2007 (UTC)

Drug delivery and Route of administration are definetively differents topics. In case the articles will be merged this has to be clearly taken into consideration. --217.95.255.143 (talk) 18:55, 28 November 2007 (UTC)

Thanks for all your comments. It seems the consensus is to not merge. I will remove the tags. -- aBSuRDiST -^T ☺ ^C- 12:27, 24 February 2008 (UTC)