Vincamine

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Vincamine
Vincamine.svg
Vincamine ball-and-stick animation.gif
Systematic (IUPAC) name
(3α,14β,16α)-14,15-dihydro-
14-hydroxyeburnamenine-14-carboxylic acid methyl ester
OR
methyl (15R,17S,19R)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2(7),3,5,8(18)-tetraene-17-carboxylate
Clinical data
AHFS/Drugs.com International Drug Names
Legal status ?
Identifiers
CAS number 1617-90-9 YesY
ATC code C04AX07
PubChem CID 15376
IUPHAR ligand 349
ChemSpider 14635 N
UNII 996XVD0JHT YesY
KEGG D08677 YesY
ChEMBL CHEMBL1165342 N
Chemical data
Formula C21H26N2O3 
Mol. mass 354.44 g/mol
 N (what is this?)  (verify)

Vincamine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) . Generic drugs containing vincamine exist in specific regions. Most common drug preparations are in the sustained release forms. Vincamine is a monoterpenoid indole alkaloid found in the leaves of Vinca minor, comprising about 25-65% of the indole alkaloids found in Vinca minor by weight. It can be synthesized from related alkaloids.[1]

Vincamine is often used as a nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such as piracetam) for a variety of purposes.

References[edit]

  1. ^ "Indole Alkaloids". Ullmann's Encyclopedia of Industrial Chemistry (Fifth ed.). Wiley-VCH. 1985. p. 393. ISBN 3-527-20100-9. 

External links[edit]

See also[edit]