Vincamine
 |
|
|---|---|
| Systematic (IUPAC) name | |
| (3α,14β,16α)-14,15-dihydro- 14-hydroxyeburnamenine-14-carboxylic acid methyl ester OR methyl (15R,17S,19R)-15-ethyl-17-hydroxy-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2(7),3,5,8(18)-tetraene-17-carboxylate |
|
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 1617-90-9  |
| ATC code | C04AX07 |
| PubChem | CID 15376 |
| IUPHAR ligand | 349 |
| ChemSpider | 14635  |
| UNII | 996XVD0JHT |
| KEGG | D08677 |
| Chemical data | |
| Formula | C21H26N2O3 |
| Mol. mass | 354.44 g/mol |
| SMILES | eMolecules & PubChem |
|
|
 (what is this?) (verify) |
|
Vincamine is a peripheral vasodilator that increases blood flow to the brain (sold under the trademark Oxybral SR) . Generic drugs containing vincamine exist in specific regions. Most common drug preparations are in the sustained release forms. Vincamine is an indole alkaloid (specifically a tryptamine) found in the leaves of Vinca minor, comprising about 25-65% of the indole alkaloids found in Vinca minor by weight. It is also found in the species Catharanthus roseus.[1] It can be synthesized from related alkaloids.[2]
Vincamine is often used as a nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such as piracetam) for a variety of purposes.
[edit] References
- ^ Cook, P.; James, I. (1981). "Cerebral Vasodilators". New England Journal of Medicine 305 (26): 1560–1564. doi:10.1056/NEJM198112243052604. PMID 7031468.
- ^ "Indole Alkaloids". Ullmann's Encyclopedia of Industrial Chemistry (Fifth ed.). Wiley-VCH. 1985. p. 393. ISBN 3-527-20100-9.
[edit] External links
- "Vincamine MSDS" (pdf). http://www.mpbio.com/includes/msds/ansi/en/158295-EN-ANSI.pdf.
- Chemical Selection Working Group. "Vincamine - 1617-90-9" (pdf). Summary of Data for Chemical Selection. NIH - United States National Institutes of Health. http://ntp-server.niehs.nih.gov/ntp/htdocs/Chem_Background/ExSumPdf/Vincamine.pdf.
[edit] See also
|
|||||||||||||||||||||||||
 |
This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it. |
