Zuska's disease

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Zuska's disease (also known as lactiferous fistula, subareolar abscess, periductal mastitis,[1][2] and Zuska–Atkins disease[3]) is a rare recurrent condition characterized by draining abscesses around the nipple. Smoking is a predisposing factor. It can mimic carcinoma of breast and is often misdiagnosed and mistreated, occasionally resulting in unnecessary mastectomy. Symptoms include swelling or subareolar mass, a draining fistula from behind the areola, nipple retraction, thick discharge from the nipple, or painful discharge.[1] It is treated by antibiotics and surgical excision of breast.[4]

The definitive therapy involved excision of the fistula and all of the retroareolar fibroglandular tissue, along with ductal tissue within the nipple.[5]

It was characterized by Joseph Zuska in 1951.[6]

See also[edit]


  1. ^ a b Guadagni M, Nazzari G (April 2008). "Zuska's disease". G Ital Dermatol Venereol 143 (2): 157–60. PMID 18833042. 
  2. ^ Passaro ME, Broughan TA, Sebek BA, Esselstyn CB (January 1994). "Lactiferous fistula". J. Am. Coll. Surg. 178 (1): 29–32. PMID 8156113. 
  3. ^ Singletary, S. Eva; Robb, Geoffrey L. (2004). Advanced Therapy of Breast Disease. Hamilton, Ont: B.C. Decker. p. 4. ISBN 1-55009-262-6. 
  4. ^ Bhat, Sriram (2010). Zuska's disease. New Delhi, India: Jaypee Publications. p. 563. 
  5. ^ Passar, M. et al. (1993). "Lactiferous Fistula." Journal of the American College of Surgery178(1), 29–32.
  6. ^ Zuska JJ, Crile G, Ayres WW (March 1951). "Fistulas of lactifierous ducts". Am. J. Surg. 81 (3): 312–7. doi:10.1016/0002-9610(51)90233-4. PMID 14819475. 

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External websites[edit]

Zuska's Disease