D-DOPA: Difference between revisions

d-DOPA
Names
	IUPAC name (2R)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid
Identifiers
CAS Number	5796-17-8 ;
3D model (JSmol)	Interactive image;
ChemSpider	83260;
ECHA InfoCard	100.024.858
PubChem CID	92222;
UNII	8T862R29FY ;
CompTox Dashboard (EPA)	DTXSID70206673 ;
	InChI InChI=1/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m1/s1 Key: WTDRDQBEARUVNC-ZCFIWIBFBC;
	SMILES O=C(O)[C@H](N)Cc1cc(O)c(O)cc1;
Properties
Chemical formula	C9H11NO4
Molar mass	197.19 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

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Revision as of 14:31, 3 June 2022

d-DOPA (d-3,4-dihydroxyphenylalanine; dextrodopa) is similar to l-DOPA (levodopa), but with opposite chirality. Levo- and dextro- rotation refer to a molecule's ability to rotate planes of polarized light in one or the other direction. Whereas l-DOPA is moderately effective in the treatment of Parkinson's disease (PD) and dopamine-responsive dystonia (DRD) by stimulating the production of dopamine in the brain, d-DOPA is biologically inactive.

References

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-'''{{sm|d}}-DOPA''' ('''{{sm|d}}'''-3,4-'''d'''ihydr'''o'''xy'''p'''henyl'''a'''lanine; '''dextrodopa''') is similar to [[L-DOPA|{{sm|l}}-DOPA]] (levodopa), but with opposite [[chirality (chemistry)|chirality]]. [[levorotation|Levo-]] and [[dextrorotation|dextro-]] rotation refer to a molecule's ability to rotate planes of [[polarized light]] in one or the other direction. Whereas {{sm|l}}-DOPA is moderately effective in the [[therapy|treatment]] of [[Parkinson's disease]] (PD) and [[Dopamine-responsive dystonia]] (DRD) by stimulating the production of dopamine in the brain, {{sm|d}}-DOPA is [[biologically]] inactive.
+'''{{sm|d}}-DOPA''' ('''{{sm|d}}'''-3,4-'''d'''ihydr'''o'''xy'''p'''henyl'''a'''lanine; '''dextrodopa''') is similar to [[L-DOPA|{{sm|l}}-DOPA]] (levodopa), but with opposite [[chirality (chemistry)|chirality]]. [[levorotation|Levo-]] and [[dextrorotation|dextro-]] rotation refer to a molecule's ability to rotate planes of [[polarized light]] in one or the other direction. Whereas {{sm|l}}-DOPA is moderately effective in the [[therapy|treatment]] of [[Parkinson's disease]] (PD) and [[dopamine-responsive dystonia]] (DRD) by stimulating the production of dopamine in the brain, {{sm|d}}-DOPA is [[biologically]] inactive.
 ==See also==