User:Ulrikelovesscience/Ralf Jungmann: Difference between revisions
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==Career and research== |
==Career and research== |
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Between 2011 and 2014, Ralf Jungmann served as a [[postdoctoral researcher]] at the [[Wyss Institute for Biologically Inspired Engineering]] at [[Harvard University]], working under the guidance of Peng Yin and William M Shih. |
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Between 2010 and 2016, Lakadamyali was a Group Leader at [[ICFO|ICFO - The Institute of Photonic Sciences]] in [[Barcelona]], [[Spain]], holding a Junior (2010-2015) and Senior (2015-2016) Group Leader position, respectively. Her group's superresolution microscopy study investigating the genome gained widespread attention. It reveals that our genome needs to be regularly packaged and links these packaging differences to stem cell state.<ref>{{Cite journal |last1=Ricci |first1=Maria Aurelia |last2=Manzo |first2=Carlo |last3=García-Parajo |first3=María Filomena |last4=Lakadamyali |first4=Melike |last5=Pia Cosma |first5=Maria |date=12 March 2015 |title=Chromatin Fibers Are Formed by Heterogeneous Groups of Nucleosomes In Vivo |journal=[[Cell (journal)|Cell]] |volume=160 |issue=6 |pages=1145–1158 |doi=10.1016/j.cell.2015.01.054|doi-access=free |pmid=25768910 |hdl=10803/298724 |hdl-access=free }}</ref><ref>{{cite web|url=https://www.youtube.com/watch?v=5KSr-giy8qo |title=Nucleosome clutches / Cell, March 12, 2015 (Vol. 160, Issue 6) |publisher=YouTube |date= |accessdate=2023-09-04}}</ref><ref>{{cite web|url=https://www.crg.eu/en/news/super-resolution-microscopes-reveal-link-between-genome-packaging-and-cell-pluripotency |title=Centre for Genomic Regulation Website |publisher=Crg.eu |date=2015-03-12 |accessdate=2023-09-04}}</ref> |
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In 2014, Jungmann returned to the Germany to work as a Research group Leader at the [[Max Planck Institute of Biochemistry]] and the [[Ludwig Maximilian University of Munich]]. |
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Jungmann's professional career advanced significantly, with him being promoted to different positions throughout the years. He was appointed as an [[Associate professor|Associate Professor]] (Physics) Tenure Track in 2016, followed by his promotion to Associate Professor (Physics) with Tenure in 2021. In 2023, he was appointed as [[Professor|Full Professor]] (Physics) and Chair for Molecular Physics of Life. |
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Ralf Jungmann's research primarily focuses on developing and applying new biophysical and imaging techniques to investigate the organization and function of biological systems at the molecular level. He is particularly interested in developing super-resolution microscopy techniques that allow for the precise localization and tracking of individual molecules within cells. His work has important applications in the study of various biological processes, including gene expression, protein interactions, and cellular signaling. Jungmann's research has also contributed to the development of nanotechnology and DNA-based computing. Overall, his research aims to deepen our understanding of the fundamental principles underlying biological systems and to develop new tools for biomedical research. |
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Lakadamyali's area of research is focused on examining biology at the level of its macromolecular machines. She aims to obtain a quantitative and biophysical comprehension of how these machines propel critical cell biological processes.<ref>{{cite web|url=https://academic.oup.com/nar/article/50/1/175/6462398 |title=Super resolution microscopy reveals how elongating RNA polymerase II and nascent RNA interact with nucleosome clutches | Nucleic Acids Research | Oxford Academic |publisher=Academic.oup.com |date= |accessdate=2023-09-04}}</ref><ref>{{cite journal|title=Mesoscale Modeling and Single-Nucleosome Tracking Reveal Remodeling of Clutch Folding and Dynamics in Stem Cell Differentiation |date= 2021|doi=10.1016/j.celrep.2020.108614 |last1=Gómez-García |first1=Pablo Aurelio |last2=Portillo-Ledesma |first2=Stephanie |last3=Neguembor |first3=Maria Victoria |last4=Pesaresi |first4=Martina |last5=Oweis |first5=Walaa |last6=Rohrlich |first6=Talia |last7=Wieser |first7=Stefan |last8=Meshorer |first8=Eran |last9=Schlick |first9=Tamar |last10=Cosma |first10=Maria Pia |last11=Lakadamyali |first11=Melike |journal=Cell Reports |volume=34 |issue=2 |pmid=33440158 |pmc=7842188 }}</ref><ref>{{Cite journal |last1=Lakadamyali |first1=Melike |last2=Cosma |first2=Maria Pia |date= 2020|title=Visualizing the genome in high resolution challenges our textbook understanding |url=https://www.nature.com/articles/s41592-020-0758-3 |journal=Nature Methods |language=en |volume=17 |issue=4 |pages=371–379 |doi=10.1038/s41592-020-0758-3 |pmid=32123395 |issn=1548-7105|hdl=10230/43808 |s2cid=211729851 |hdl-access=free }}</ref> Hence, she is also involved in designing sophisticated microscopy techniques that strive to surmount the current limitations of existing methods, thereby enabling them to observe the macromolecular machinery of the cell in motion with superior spatiotemporal resolution.<ref>{{cite web|url=https://www.med.upenn.edu/apps/faculty/index.php/g275/p8946783 |title=Melike Lakadamyali | Faculty | About Us | Perelman School of Medicine | Perelman School of Medicine at the University of Pennsylvania |publisher=Med.upenn.edu |date= |accessdate=2023-09-04}}</ref><ref>{{cite journal|title=Technological advances in super-resolution microscopy to study cellular processes |date=2022-01-20 |doi=10.1016/j.molcel.2021.12.022 |last1=Bond |first1=Charles |last2=Santiago-Ruiz |first2=Adriana N. |last3=Tang |first3=Qing |last4=Lakadamyali |first4=Melike |journal=Molecular Cell |volume=82 |issue=2 |pages=315–332 |pmid=35063099 |pmc=8852216 }}</ref><ref>{{Cite journal |last1=Hugelier |first1=Siewert |last2=Colosi |first2=P.L. |last3=Lakadamyali |first3=Melike |date=2023-05-09 |title=Quantitative Single-Molecule Localization Microscopy |journal=Annual Review of Biophysics |language=en |volume=52 |issue=1 |pages=139–160 |doi=10.1146/annurev-biophys-111622-091212 |issn=1936-122X|doi-access=free |pmid=37159293 }}</ref> |
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Ralf Jungmann is well known for his contributions to the development of super-resolution microscopy techniques, particularly for his work on DNA-PAINT, a super-resolution technique that uses short DNA strands to label and locate specific molecules within a sample with high precision. This technique has important applications in the study of biological systems and has been used to uncover new insights into the structure and function of cells. Additionally, he is known for his work on developing and applying new biophysical and imaging techniques to investigate the organization and function of biological systems at the molecular level. |
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Lakadamyali is a well-known [[microscopist]] and [[Biophysics|biophysicist]]. Hence, she is frequently invited to speak at workshops<ref>{{cite web|url=https://www.embl.org/about/info/course-and-conference-office/events/iss23-01/#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2 |title=In situ structural biology: from cryo-EM to multi-scale modelling – Course and Conference Office |publisher=Embl.org |date= |accessdate=2023-09-04}}</ref><ref>{{cite web|author=Home |url=https://www.picoquant.com/events/detail/single-molecule-workshop-2016#description |title=22nd Single Molecule Workshop |publisher=PicoQuant |date= |accessdate=2023-09-04}}</ref> and [[conference]]s<ref>{{cite web|url=https://www.biologists.com/meetings/celldynamics2023-2/ |title=JCS2023: Imaging Cell Dynamics - The Company of Biologists |publisher=Biologists.com |date= |accessdate=2023-09-04}}</ref><ref>{{cite web|url=https://www.embl.org/about/info/course-and-conference-office/events/ees19-09/#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2 |title=Seeing is Believing – Imaging the Molecular Processes of Life – Course and Conference Office |publisher=Embl.org |date=2019-10-12 |accessdate=2023-09-04}}</ref><ref>{{Cite web |title=Genome Organization & Nuclear Function 2022 {{!}} CSHL |url=https://meetings.cshl.edu/meetings.aspx?meet=NUCLEUS&year=22 |access-date=2023-09-04 |website=meetings.cshl.edu}}</ref> in the field. |
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Jungmann is currently an associate editor for the journals [[ACS Nano]] and [[Nanoscale (journal)|Nanoscale]], and he also serves on the editorial board of [[Biophysical Journal]] and [[Scientific Reports]]. |
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Since 2019, Lakadamyali has been a Reviewing [[Editing|Editor]] (Cell Biology) at [[eLife]].<ref>{{Cite web |title=Editors for Cell Biology |url=https://elifesciences.org/about/people/cell-biology |access-date=2023-09-04 |website=eLife |language=en}}</ref> |
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==Awards and honours== |
==Awards and honours== |
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Revision as of 16:31, 7 June 2024
Ralf Jungmann | |
|---|---|
| Nationality | German |
| Alma mater | |
| Known for | DNA-PAINT |
| Scientific career | |
| Fields | Super-Resolution Microscopy, DNA Nanotechnology, Biophysics, Single Molecule Experiments |
| Institutions | |
| Thesis | DNA origami as a molecular platform for bionanotechnology (2010) |
| Doctoral advisor | Friedrich Simmel |
| Website | Jungmann Lab |
Ralf Jungmann is a German physicist and Full Professor (Physics) and Chair for Molecular Physics of Life at the Ludwig Maximilian University of Munich, Germany. He is known for his contributions to the development of super-resolution microscopy techniques. In particular, he is known for his work on DNA-PAINT, a super-resolution technique that uses short DNA strands to label and locate specific molecules within a sample with high precision. This technique has important applications in the study of biological systems and has been used to uncover new insights into the structure and function of cells.
Education
Between 2001 and 2006, Jungmann pursued a degree in Physics at Saarland University and the University of California, Santa Barbara. During his time at the latter institution, he conducted his Diploma thesis under the guidance of Paul K. Hansma. Subsequently, from 2007 to 2010, he completed his Ph.D. in Physics at Technical University of Munich, where he worked in the laboratory of Friedrich Simmel.
Career and research
Between 2011 and 2014, Ralf Jungmann served as a postdoctoral researcher at the Wyss Institute for Biologically Inspired Engineering at Harvard University, working under the guidance of Peng Yin and William M Shih.
In 2014, Jungmann returned to the Germany to work as a Research group Leader at the Max Planck Institute of Biochemistry and the Ludwig Maximilian University of Munich.
Jungmann's professional career advanced significantly, with him being promoted to different positions throughout the years. He was appointed as an Associate Professor (Physics) Tenure Track in 2016, followed by his promotion to Associate Professor (Physics) with Tenure in 2021. In 2023, he was appointed as Full Professor (Physics) and Chair for Molecular Physics of Life.
Ralf Jungmann's research primarily focuses on developing and applying new biophysical and imaging techniques to investigate the organization and function of biological systems at the molecular level. He is particularly interested in developing super-resolution microscopy techniques that allow for the precise localization and tracking of individual molecules within cells. His work has important applications in the study of various biological processes, including gene expression, protein interactions, and cellular signaling. Jungmann's research has also contributed to the development of nanotechnology and DNA-based computing. Overall, his research aims to deepen our understanding of the fundamental principles underlying biological systems and to develop new tools for biomedical research.
Ralf Jungmann is well known for his contributions to the development of super-resolution microscopy techniques, particularly for his work on DNA-PAINT, a super-resolution technique that uses short DNA strands to label and locate specific molecules within a sample with high precision. This technique has important applications in the study of biological systems and has been used to uncover new insights into the structure and function of cells. Additionally, he is known for his work on developing and applying new biophysical and imaging techniques to investigate the organization and function of biological systems at the molecular level.
Jungmann is currently an associate editor for the journals ACS Nano and Nanoscale, and he also serves on the editorial board of Biophysical Journal and Scientific Reports.
Awards and honours
References