Progressive outer retinal necrosis: Difference between revisions
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'''Progressive outer retinal necrosis''' (PORN), also known as '''Varicella zoster virus retinitis''' (VZVR)<ref name="Moorthy">Moorthy RS, Weinberg DV, Teich SA, Berger BB, Minturn JT, Kumar S, Rao NA, Fowell SM, Loose IA, Jampol LM. [http://bjo.bmjjournals.com/cgi/content/full/81/3/189 "Management of varicella zoster virus retinitis in AIDS."] ''Br J Ophthalmol.'' 1997 Mar;81(3):189-94. PMID 9135381</ref>, is an aggressive, [[Necrosis|necrotizing]] [[inflammation]] of the [[eye]]'s [[retina]] caused by herpes [[varicella zoster virus]]. It is typically found in people with advanced [[AIDS]], but has also been reported in those who are severely immunocompromised due to [[chemotherapy]]<ref>Copeland R, Phillpotts B. [http://www.emedicine.com/OPH/topic261.htm "Ocular Manifestations of HIV."] eMedicine.com. January 20, 2005.</ref>. |
'''Progressive outer retinal necrosis''' (PORN), also known as '''Varicella zoster virus retinitis''' (VZVR)<ref name="Moorthy">Moorthy RS, Weinberg DV, Teich SA, Berger BB, Minturn JT, Kumar S, Rao NA, Fowell SM, Loose IA, Jampol LM. [http://bjo.bmjjournals.com/cgi/content/full/81/3/189 "Management of varicella zoster virus retinitis in AIDS."] ''Br J Ophthalmol.'' 1997 Mar;81(3):189-94. PMID 9135381</ref>, is an aggressive, [[Necrosis|necrotizing]] [[inflammation]] of the [[eye]]'s [[retina]] caused by herpes [[varicella zoster virus]]. It is typically found in people with advanced [[AIDS]], but has also been reported in those who are severely immunocompromised due to [[chemotherapy]]<ref>Copeland R, Phillpotts B. [http://www.emedicine.com/OPH/topic261.htm "Ocular Manifestations of HIV."] eMedicine.com. January 20, 2005.</ref>. |
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Revision as of 03:09, 19 December 2008
Progressive outer retinal necrosis (PORN), also known as Varicella zoster virus retinitis (VZVR)[1], is an aggressive, necrotizing inflammation of the eye's retina caused by herpes varicella zoster virus. It is typically found in people with advanced AIDS, but has also been reported in those who are severely immunocompromised due to chemotherapy[2].
The majority of those with progressive outer retinal necrosis develop severe vision loss and blindness[3]. Systemic antiviral drugs may improve the long-term visual outcome in those with the disease[1].
References
- ^ a b Moorthy RS, Weinberg DV, Teich SA, Berger BB, Minturn JT, Kumar S, Rao NA, Fowell SM, Loose IA, Jampol LM. "Management of varicella zoster virus retinitis in AIDS." Br J Ophthalmol. 1997 Mar;81(3):189-94. PMID 9135381
- ^ Copeland R, Phillpotts B. "Ocular Manifestations of HIV." eMedicine.com. January 20, 2005.
- ^ Holland GN. "The progressive outer retinal necrosis syndrome." Int Ophthalmol. 1994;18(3):163-5. PMID 7852023.