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[[Image:schambergdisease-26male.png|thumb|right|alt=Rust-colored spots on the left lower leg and left foot of a 26-year-old Caucasian male typical of Schamberg disease.|Rust-colored spots typical of ''[[Schamberg disease]]'' on the lower left leg and left foot of a 26-year-old Caucasian male.]]
[[Image:schambergdisease-26male.png|thumb|right|alt=Rust-colored spots on the left lower leg and left foot of a 26-year-old Caucasian male typical of Schamberg disease.|Rust-colored spots typical of Schamberg disease on the lower left leg and left foot of a 26-year-old Caucasian male.]]


'''Schamberg Disease''', (also known as "Progressive pigmentary dermatosis of Schamberg,"<ref name="Bolognia" /> "Purpura pigmentosa progressiva,"<ref name="Bolognia" /> and "Schamberg's purpura"<ref name="Bolognia">{{cite book |author=Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages= |isbn=1-4160-2999-0 |oclc= |doi= |accessdate=}}</ref>) is a [[chronic (medicine)|chronic]] discoloration of the skin found in people of all ages, usually affecting the legs. It slowly spreads throughout the body, and is most common in males.<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref>{{rp|829}}
'''Schamberg Disease''', (also known as "Progressive pigmentary dermatosis of Schamberg,"<ref name="Bolognia" /> "Purpura pigmentosa progressiva,"<ref name="Bolognia" /> and "Schamberg's purpura"<ref name="Bolognia">{{cite book |author=Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages= |isbn=1-4160-2999-0 |oclc= |doi= |accessdate=}}</ref>) is a [[chronic (medicine)|chronic]] discoloration of the skin found in people of all ages, usually affecting the legs. It slowly spreads throughout the body, and is most common in males.<ref name="Andrews">{{cite book |author=James, William D.; Berger, Timothy G.; et al. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=}}</ref>{{rp|829}}

Revision as of 01:21, 18 April 2010

Schamberg disease
SpecialtyDermatology Edit this on Wikidata
Rust-colored spots on the left lower leg and left foot of a 26-year-old Caucasian male typical of Schamberg disease.
Rust-colored spots typical of Schamberg disease on the lower left leg and left foot of a 26-year-old Caucasian male.

Schamberg Disease, (also known as "Progressive pigmentary dermatosis of Schamberg,"[1] "Purpura pigmentosa progressiva,"[1] and "Schamberg's purpura"[1]) is a chronic discoloration of the skin found in people of all ages, usually affecting the legs. It slowly spreads throughout the body, and is most common in males.[2]: 829 

Definition

Schamberg's disease, or progressive pigmented purpuric dermatitis, is a chronic discoloration of the skin which usually affects the legs and often spreads slowly. This disease is more common in males and may occur at any age from childhood onward.

Cause

Schamberg's disease is caused by leaky blood vessels near the surface of the skin, capillaries, which allow red blood cells to slip through into the skin. The red blood cells in the skin then fall apart and release their iron which causes a rust color, this accounts for the orange tint of the rash.

Symptoms

The lesions are most frequent on the lower limbs, but may occur anywhere on the body, including the hands. They may vary in number. They consist of irregular patches of orange or brown pigmentation due to hemosiderin (iron), with characteristic "cayenne pepper" spots appearing within and at the edge of old lesions. There are usually no symptoms, although there may be some slight itching. The eruption may persist for many years. The pattern of the eruption changes, with slow extension and often some clearing of the original lesions.

Treatment

There is no cure for Schamberg's disease; however, the itching can be controlled by a cortisone cream.

See also

References

  1. ^ a b c Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.{{cite book}}: CS1 maint: multiple names: authors list (link)
  2. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. {{cite book}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)