European Molecular Biology Laboratory: Difference between revisions
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{{Infobox Institute |
{{Infobox Institute |
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|name = European Molecular Biology Laboratory |
|name = European Molecular Biology Laboratory |
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|image = [[ |
|image = [[File:EMBL Logo.png|250px]] |
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|established = 1974 |
|established = 1974 |
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|head_label = Director General |
|head_label = Director General |
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The '''European Molecular Biology Laboratory''' ('''EMBL''') is a [[molecular biology]] research institution supported by 20 European countries and Australia as associate member state. EMBL was created in 1974 and is an [[intergovernmental organisation]] funded by public research money from its member states. Research at EMBL is conducted by approximately 85 independent groups covering the spectrum of [[molecular biology]]. The Laboratory operates from five sites: the main Laboratory in [[Heidelberg]], and Outstations in [[Hinxton]] (the [[European Bioinformatics Institute ]] ('''EBI''')), [[Grenoble]], [[Hamburg]], and [[Monterotondo]] near Rome.<ref name="Science2007">{{cite journal |journal=Science |date=12 December 1997 |volume=278 |pmid=9417631 |issue=5345 |pages=1875–1876| doi=10.1126/science.278.5345.1875 |title=MOLECULAR BIOLOGY: EMBL's Outward Expansion Strains Its Core Facility| first=Nigel |last=Williams}}</ref> Each of the sites has a specific research field. The EBI is a hub for bioinformatic research and services. At [[Grenoble]] and [[Hamburg]], research is focused on structural biology. At [[Monterotondo]], mouse models are used because they are ideal models for exploring human diseases. At the headquarters in [[Heidelberg]], there are units in Cell Biology and Biophysics, Developmental Biology, Genome Biology and Structural and Computational Biology as well as service groups complementing the aforementioned research fields. |
The '''European Molecular Biology Laboratory''' ('''EMBL''') is a [[molecular biology]] research institution supported by 20 European countries and Australia as associate member state. EMBL was created in 1974 and is an [[intergovernmental organisation]] funded by public research money from its member states. Research at EMBL is conducted by approximately 85 independent groups covering the spectrum of [[molecular biology]]. The Laboratory operates from five sites: the main Laboratory in [[Heidelberg]], and Outstations in [[Hinxton]] (the [[European Bioinformatics Institute ]] ('''EBI''')), [[Grenoble]], [[Hamburg]], and [[Monterotondo]] near Rome.<ref name="Science2007">{{cite journal |journal=Science |date=12 December 1997 |volume=278 |pmid=9417631 |issue=5345 |pages=1875–1876| doi=10.1126/science.278.5345.1875 |title=MOLECULAR BIOLOGY: EMBL's Outward Expansion Strains Its Core Facility| first=Nigel |last=Williams}}</ref> |
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==Research at the EMBL== |
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Each of the sites has a specific research field. The EBI is a hub for bioinformatic research and services. At [[Grenoble]] and [[Hamburg]], research is focused on structural biology. At [[Monterotondo]], mouse models are used because they are ideal models for exploring human diseases. At the headquarters in [[Heidelberg]], there are units in Cell Biology and Biophysics, Developmental Biology, Genome Biology and Structural and Computational Biology as well as service groups complementing the aforementioned research fields. |
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Australia has been EMBL's associated member state since 2008 and has intense collaborations with EMBL. EMBL Australia's aim is to promote Australia’s international competitiveness in the life sciences through collaborations, partnerships and training programmes. |
Australia has been EMBL's associated member state since 2008 and has intense collaborations with EMBL. EMBL Australia's aim is to promote Australia’s international competitiveness in the life sciences through collaborations, partnerships and training programmes. |
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Many scientific breakthroughs have been made at EMBL, most notably the first systematic genetic analysis of embryonic development in the fruit fly by [[Christiane Nüsslein-Volhard]] and [[Eric Wieschaus]], for which they were awarded the Nobel Prize for Me |
Many scientific breakthroughs have been made at EMBL, most notably the first systematic genetic analysis of embryonic development in the fruit fly by [[Christiane Nüsslein-Volhard]] and [[Eric Wieschaus]], for which they were awarded the Nobel Prize for Me |
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dicine in 1995. |
dicine in 1995. |
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[[Image:EMBL Heidelberg.jpg|190px|right|thumbnail|Old EMBL entrance]] |
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===European Bioinformatics Institute=== |
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EMBL's outstation EBI (European Bioinformatics Institute) develops and maintains a large number of databases which are free of charge for the scientific community. Some of its major databases: |
EMBL's outstation EBI (European Bioinformatics Institute) develops and maintains a large number of databases which are free of charge for the scientific community. Some of its major databases: |
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Revision as of 19:55, 22 March 2011
| File:EMBL Logo.png | |
| Established | 1974 |
|---|---|
| Director General | Iain Mattaj |
| Faculty | ~95 |
| Location | |
| Website | www.embl.org |
The European Molecular Biology Laboratory (EMBL) is a molecular biology research institution supported by 20 European countries and Australia as associate member state. EMBL was created in 1974 and is an intergovernmental organisation funded by public research money from its member states. Research at EMBL is conducted by approximately 85 independent groups covering the spectrum of molecular biology. The Laboratory operates from five sites: the main Laboratory in Heidelberg, and Outstations in Hinxton (the European Bioinformatics Institute (EBI)), Grenoble, Hamburg, and Monterotondo near Rome.[1]
Research at the EMBL
Each of the sites has a specific research field. The EBI is a hub for bioinformatic research and services. At Grenoble and Hamburg, research is focused on structural biology. At Monterotondo, mouse models are used because they are ideal models for exploring human diseases. At the headquarters in Heidelberg, there are units in Cell Biology and Biophysics, Developmental Biology, Genome Biology and Structural and Computational Biology as well as service groups complementing the aforementioned research fields.
Australia has been EMBL's associated member state since 2008 and has intense collaborations with EMBL. EMBL Australia's aim is to promote Australia’s international competitiveness in the life sciences through collaborations, partnerships and training programmes.
The cornerstones of EMBL's mission are manifold. Basic research in molecular biology and molecular medicine is performed; scientists, students and visitors at all levels are trained; vital services to scientists in the member states are offered; new instruments and methods in the life sciences are developed; and there is an active engagement in technology transfer.
In March 2010, the EMBL Advanced Training Centre (ATC) was inaugurated on the main campus in Heidelberg. It is a striking building shaped in the form of a double helix and it hosts world-class conferences and provides state-of-the-art training opportunities.
The EMBL International PhD Programme has a student body of about 200. Since 1997 it has the right to award its own degree.
EMBL also also runs an active Science and Society Programme which offers activities and events on current questions in life science research for the general public and the scientific community.
Many scientific breakthroughs have been made at EMBL, most notably the first systematic genetic analysis of embryonic development in the fruit fly by Christiane Nüsslein-Volhard and Eric Wieschaus, for which they were awarded the Nobel Prize for Me dicine in 1995.
European Bioinformatics Institute
EMBL's outstation EBI (European Bioinformatics Institute) develops and maintains a large number of databases which are free of charge for the scientific community. Some of its major databases:
- The Array Express is a database of functional genomics experiments which you can query and download.
- The ClusTr database contains classification of proteins which are present in the Uniprot and IPI (International Protein Index) according to groups of related groups.
- ENSEMBL contains genome databases for vertebrates and other eukaryotic species.
- Genome Review Database provides annotated view of the genomic sequence of organisms with completely deciphered genomes. Currently, it contains the genomes of archaea, bacteria, bacteriophages and selected eukaryota.
- GO is the Gene Ontology consortium. It contains descriptions of the molecular function, biological process and cellular component of gene products.
- Quick GO is a fast web-based browser for Gene Ontology terms and annotations.
- MEDLINE is a bibliographic database covering the fields of medicine, nursing, dentistry, veterinary medicine, the health care system, and the pre-clinical sciences. MEDLINE contains bibliographic citations and author abstracts from about 5,000 biomedical journals published in the United States and 70 other countries. It is originally part of NLM (National Library of Medicine, US)
- OMIM contains information on all known mendelian disorders and over 12,000 genes and this is also actually NCBI’s premier database.
- OLS or the Ontology Lookup Service allows users to look up ambiguous terms. It provides definitions and essential details.
- The PRIDE PRoteomics IDEntifications database is a centralized public data repository for proteomics data. It provides a public repository for protein and peptide identifications together with the evidence supporting these identifications.
- IntEnz stands for Integrated relational Enzyme database. It is also a freely available resource on enzyme nomenclature.
- Intact is a freely available database providing analysis tools for protein interaction.
- UNIPROT is a resource of protein sequence and functional information. UniProt has four components: the UniProt Knowledgebase (UniProtKB), UniProt Reference Clusters (UniRef), The UniProt Archive (UniParc), and UniProt Metagenomic and Environmental Sequences (UniMES).
- SWISSPROT- The Swiss-Prot Protein Sequence Database is a database of protein sequences. The data in Swiss-Prot are derived from translations of DNA sequences from the EMBL Nucleotide Sequence Database, adapted from the Protein Information Resource (PIR) collection, extracted from the literature and directly submitted by researchers.
- TrEMBL is a protein sequence database that compliments the SWISSP.
Notes
- ^ Williams, Nigel (12 December 1997). "MOLECULAR BIOLOGY: EMBL's Outward Expansion Strains Its Core Facility". Science. 278 (5345): 1875–1876. doi:10.1126/science.278.5345.1875. PMID 9417631.
See also
- European Molecular Biology Organization (EMBO)
- National Center for Biotechnology Information (NCBI)
- Fotis Kafatos
- Matthias Hentze
External links
- EMBL homepage
- EMBL Heidelberg homepage
- EMBL Hamburg homepage
- EMBL Grenoble homepage
- EMBL Monterotondo homepage
- European Bioinformatics Institute homepage
- Science and Society Programme
- EMBL International PhD Programme
- Postdoctoral Programme
- European Learning Laboratory for the Life Sciences (ELLS)
- EMBL and University of Heidelberg Molecular Medicine Partnership Unit (MMPU)
- EMBL Australia homepage
Coordinates
Coordinates for EMBL main laboratory in Heidelberg: 49°23′5.28″N 8°42′37.15″E / 49.3848000°N 8.7103194°E
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