Spleen transplantation: Difference between revisions
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'''Spleen transplantation''' is the transfer of [[spleen]] or spleen fragments from one individual to another. It is under research for induction of immunological tolerance for other [[Organ transplant|transplanted organs]]. Success has been achieved in [[rodent]] models. Recently, evidence has been obtained for a tolerogenic effect of a spleen transplant in [[miniature swine]] |
'''Spleen transplantation''' is the transfer of [[spleen]] or spleen fragments from one individual to another. It is under research for induction of immunological tolerance for other [[Organ transplant|transplanted organs]]. Success has been achieved in [[rodent]] models. Recently, evidence has been obtained for a tolerogenic effect of a spleen transplant in [[miniature swine]] |
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[http://repub.eur.nl/resource/pub_10508/index.html (Frank JMF Dor, PhD thesis)]. Also, the spleen harbors primitive hematopoietic progenitor cells. Spleen transplantation surgery has been performed on humans with mixed results.<ref name=Wu>{{cite journal|last1=Wu et al.|title=Graft-versus-host disease after intestinal and multivisceral transplantation.|journal=Transplantation|date=January 2011|volume=91|issue=2|pages=219-224|pmid=21076376|url=http://www.ncbi.nlm.nih.gov/pubmed/21076376}}</ref><ref name=Deierhoi>{{cite journal|last1=Deierhoi et al.|title=Lethal graft-versus-host disease in a recipient of a pancreas-spleen transplant.|journal=Transplantation|date=April 1986|volume=41|issue=4|pages=544-546|pmid=3515658|url=http://www.ncbi.nlm.nih.gov/pubmed/3515658}}</ref> |
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[http://repub.eur.nl/resource/pub_10508/index.html (Frank JMF Dor, PhD thesis)]. Also, the spleen harbors primitive hematopoietic progenitor cells. |
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{{Organ transplantation}} |
{{Organ transplantation}} |
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Revision as of 22:25, 4 February 2015
| Spleen transplantation | |
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| ICD-9-CM | 41.94 |
Spleen transplantation is the transfer of spleen or spleen fragments from one individual to another. It is under research for induction of immunological tolerance for other transplanted organs. Success has been achieved in rodent models. Recently, evidence has been obtained for a tolerogenic effect of a spleen transplant in miniature swine (Frank JMF Dor, PhD thesis). Also, the spleen harbors primitive hematopoietic progenitor cells. Spleen transplantation surgery has been performed on humans with mixed results.[1][2]
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- ^ Wu; et al. (January 2011). "Graft-versus-host disease after intestinal and multivisceral transplantation". Transplantation. 91 (2): 219–224. PMID 21076376.
{{cite journal}}: Explicit use of et al. in:|last1=(help) - ^ Deierhoi; et al. (April 1986). "Lethal graft-versus-host disease in a recipient of a pancreas-spleen transplant". Transplantation. 41 (4): 544–546. PMID 3515658.
{{cite journal}}: Explicit use of et al. in:|last1=(help)