Trimethoprim/sulfadoxine: Difference between revisions
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[[Category:Animal vaccines]] |
Revision as of 14:14, 22 July 2015
Trimidox is an antibacterial agent that is used in cattle and swine to prevent and treat infections by both Gram-negative and Gram-positive bacteria.[1] The active ingredients in Trimidox are W/V trimethoprim (4%) and W/V sulfadoxine (20%), the rest of the solution is an organic solvent (40 mg of trimethoprim and 200 mg of sulfadoxine in each ml of solution).[1] This product is for veterinary use only. When used on an animal, the procedure must be done by a licensed veterinarian. It is available in three different size vials: 100ml, 250ml, and 500ml. It should be stored between 15 °C and 25 °C, and should be protected from light.
Treatment
Trimidox is used in the treatment of swine and cattle; including dairy cattle, beef cattle and veal.
According to the product label, in Cattle, Trimidox is used to treat:
- Respiratory Tract Infections such as, bovine pneumonia pasteurellosis. (shipping fever)[1]
- Alimentary Tract Infections such as salmonellosis and both enteric and septicaemic colibacillosis.[1]
- Other Infections such as, Infectious pododermatitis (foot rot) and septicaemias.[1]
In Swine, Trimidox is used to treat:
- Respiratory Tract Infections such as, bacterial pneumonias.[1]
- Alimentary Tract Infections such as, post-weaning scours and Colibacillosis.[1]
- Other Infections such as, bacterial arthritis and Mastitis-metritis-agalactia (MMA) syndrome in sows.[1]
Cautions
Trimidox is not to be used in cattle or swine that show marked liver parenchymal damage or blood dyscrasias, or those with a history of sulfonamide sensitivity.[1]
Any milk taken from an animal treated with Trimidox in the last 96 hours must not be used as food for human consumption; also treated animals must not be slaughtered for use in food for at least ten days after the last treatment of Trimidox.[1]
Side effects
There are no known significant side effects/adverse reactions for Trimidox.[1]