Michael Houghton: Difference between revisions
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After graduating with a degree in Biological Sciences from the [[University of East Anglia]] in 1972 and a PhD in Biochemistry from [[King's College London]] in 1977, Houghton joined [[G. D. Searle & Company]] before moving to [[Chiron Corporation]] in 1982.<ref name="ref904913078">{{cite book|url=http://books.google.co.uk/books?id=n5P696E7T0wC&pg=PA344&dq=dr+Michael+Houghton&hl=en&sa=X&ei=gW7IUq69IImO7AbepoG4CQ&ved=0CDkQ6AEwAQ#v=onepage&q=dr%20Michael%20Houghton&f=false|title=Liver Cirrhosis and Its Development - Google Books|publisher=books.google.co.uk|accessdate=2014-01-12}}</ref> It was at Chiron that Houghton together with colleagues [[Qui-Lim Choo]] and George Kuo, and D.W. Bradley from the [[Centers for Disease Control and Prevention]] first discovered [[Hepatitis C]]. He also discovered the [[Hepatitis D]] [[genome]].<ref>{{cite journal|last=Wang|first=KS |author2=Choo, QL |author3=Weiner, AJ |author4=Ou, JH |author5=Najarian, RC |author6=Thayer, RM |author7=Mullenbach, GT |author8=Denniston, KJ |author9=Gerin, JL |author10=Houghton, M|title=Structure, sequence and expression of the hepatitis delta (delta) viral genome|journal=Nature|date=9 October 1986|volume=323|issue=6088|pages=508–14|pmid=3762705|doi=10.1038/323508a0}}</ref> |
After graduating with a degree in Biological Sciences from the [[University of East Anglia]] in 1972 and a PhD in Biochemistry from [[King's College London]] in 1977, Houghton joined [[G. D. Searle & Company]] before moving to [[Chiron Corporation]] in 1982.<ref name="ref904913078">{{cite book|url=http://books.google.co.uk/books?id=n5P696E7T0wC&pg=PA344&dq=dr+Michael+Houghton&hl=en&sa=X&ei=gW7IUq69IImO7AbepoG4CQ&ved=0CDkQ6AEwAQ#v=onepage&q=dr%20Michael%20Houghton&f=false|title=Liver Cirrhosis and Its Development - Google Books|publisher=books.google.co.uk|accessdate=2014-01-12}}</ref> It was at Chiron that Houghton together with colleagues [[Qui-Lim Choo]] and George Kuo, and D.W. Bradley from the [[Centers for Disease Control and Prevention]] first discovered [[Hepatitis C]]. He also discovered the [[Hepatitis D]] [[genome]].<ref>{{cite journal|last=Wang|first=KS |author2=Choo, QL |author3=Weiner, AJ |author4=Ou, JH |author5=Najarian, RC |author6=Thayer, RM |author7=Mullenbach, GT |author8=Denniston, KJ |author9=Gerin, JL |author10=Houghton, M|title=Structure, sequence and expression of the hepatitis delta (delta) viral genome|journal=Nature|date=9 October 1986|volume=323|issue=6088|pages=508–14|pmid=3762705|doi=10.1038/323508a0}}</ref> |
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In 2013, Houghton's team at the University of Alberta showed that a vaccine derived from a single strain of Hepatitis C was effective against all strains of the virus. The vaccine is currently in clinical trials.<ref>{{cite web|url=http://www.ncbi.nlm.nih.gov/pubmed/23527266|date=March 19, 2013|accessdate=29 January 2016}}</ref> |
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He was awarded the [[Robert Koch Prize]] in 1993, and the [[Lasker Award]] in 2000. In 2013 he become the first person to decline the [[Canadian dollar|$]]100,000 [[Gairdner Foundation International Award]] stating "I felt that it would be unfair of me to accept this award without the inclusion of two colleagues, Dr. [[Qui-Lim Choo]] and Dr. George Kuo".<ref>{{cite web|url=http://www.folio.ualberta.ca/article.cfm?v=104208&i=104377&a=3|title=World-renowned virologist named recipient of Gairdner Award|date=March 22, 2013|accessdate=13 January 2014}}</ref><ref>{{cite web|url=http://news.nationalpost.com/2013/03/20/team-player-edmonton-scientist-turns-down-100000-baby-nobel-because-it-shut-out-colleagues/|title=Edmonton scientist turns down $100,000 ‘baby Nobel’ because it shut out colleagues|last=Boesveld|first=Sarah|date=20 March 2013|accessdate=13 January 2014}}</ref> |
He was awarded the [[Robert Koch Prize]] in 1993, and the [[Lasker Award]] in 2000. In 2013 he become the first person to decline the [[Canadian dollar|$]]100,000 [[Gairdner Foundation International Award]] stating "I felt that it would be unfair of me to accept this award without the inclusion of two colleagues, Dr. [[Qui-Lim Choo]] and Dr. George Kuo".<ref>{{cite web|url=http://www.folio.ualberta.ca/article.cfm?v=104208&i=104377&a=3|title=World-renowned virologist named recipient of Gairdner Award|date=March 22, 2013|accessdate=13 January 2014}}</ref><ref>{{cite web|url=http://news.nationalpost.com/2013/03/20/team-player-edmonton-scientist-turns-down-100000-baby-nobel-because-it-shut-out-colleagues/|title=Edmonton scientist turns down $100,000 ‘baby Nobel’ because it shut out colleagues|last=Boesveld|first=Sarah|date=20 March 2013|accessdate=13 January 2014}}</ref> |
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Revision as of 18:06, 29 January 2016
Michael Houghton | |
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| Alma mater | University of East Anglia (BSc) King's College London (PhD) |
| Known for | Hepatitis C Hepatitis D |
| Awards | Robert Koch Prize 1993 Lasker Award 2000 Gairdner Foundation International Award 2013 (declined) |
| Scientific career | |
| Fields | Microbiology Virology |
| Institutions | University of Alberta Chiron Corporation |
| Thesis | RNA Polymerases and Transcription in the Chicken Oviduct (1977) |
| Website | Michael Houghton, PhD |
Michael Houghton is a British scientist, who along with Qui-Lim Choo, George Kuo and Daniel W Bradley, co-discovered Hepatitis C in 1989. He is currently Li Ka Shing Professor of Virology, Canada Excellence Research Chair in Virology, and professor in the Department of Medical Microbiology and Immunology at the University of Alberta.[1]
After graduating with a degree in Biological Sciences from the University of East Anglia in 1972 and a PhD in Biochemistry from King's College London in 1977, Houghton joined G. D. Searle & Company before moving to Chiron Corporation in 1982.[2] It was at Chiron that Houghton together with colleagues Qui-Lim Choo and George Kuo, and D.W. Bradley from the Centers for Disease Control and Prevention first discovered Hepatitis C. He also discovered the Hepatitis D genome.[3]
In 2013, Houghton's team at the University of Alberta showed that a vaccine derived from a single strain of Hepatitis C was effective against all strains of the virus. The vaccine is currently in clinical trials.[4]
He was awarded the Robert Koch Prize in 1993, and the Lasker Award in 2000. In 2013 he become the first person to decline the $100,000 Gairdner Foundation International Award stating "I felt that it would be unfair of me to accept this award without the inclusion of two colleagues, Dr. Qui-Lim Choo and Dr. George Kuo".[5][6]
References
- ^ "MMI Faculty - Michael Houghton, PhD". Retrieved 13 January 2014.
- ^ Liver Cirrhosis and Its Development - Google Books. books.google.co.uk. Retrieved 2014-01-12.
- ^ Wang, KS; Choo, QL; Weiner, AJ; Ou, JH; Najarian, RC; Thayer, RM; Mullenbach, GT; Denniston, KJ; Gerin, JL; Houghton, M (9 October 1986). "Structure, sequence and expression of the hepatitis delta (delta) viral genome". Nature. 323 (6088): 508–14. doi:10.1038/323508a0. PMID 3762705.
- ^ . March 19, 2013 http://www.ncbi.nlm.nih.gov/pubmed/23527266. Retrieved 29 January 2016.
{{cite web}}: Missing or empty|title=(help) - ^ "World-renowned virologist named recipient of Gairdner Award". March 22, 2013. Retrieved 13 January 2014.
- ^ Boesveld, Sarah (20 March 2013). "Edmonton scientist turns down $100,000 'baby Nobel' because it shut out colleagues". Retrieved 13 January 2014.
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